Results 171 to 180 of about 6,219 (219)
AGING MEDICINE, EarlyView.Frailty was associated with decreased gray and white matter brain volumes in older adults. Synthetic MRI further revealed relaxometry alterations correlated with frailty severity across multiple clinical scales. ABSTRACT Objectives Frailty, a common condition in the elderly, is characterized by a decline in physiological reserves and an increased ...
Yuhui Chen +7 more
wiley +1 more source
Composition‐Aware Cross‐Sectional Integration for Spatial Transcriptomics
Advanced Intelligent Discovery, EarlyView.Multi‐section spatial transcriptomics demands coherent cell‐type deconvolution, domain detection, and batch correction, yet existing pipelines treat these tasks separately. FUSION unifies them within a composition‐aware latent framework, modeling reads as cell‐type–specific topics and clustering in embedding space.
Qishi Dong +5 more
wiley +1 more source
Parametric Analysis of Spiking Neurons in 16 nm Fin Field‐Effect Transistor Technology
Advanced Intelligent Discovery, EarlyView.Energy efficient computing has driven a shift toward brain‐inspired neuromorphic hardware. This study explores the design of three distinct silicon neuron topologies implemented in 16 nm fin field‐Effect transistor technology. While the Axon‐Hillock design achieves gigahertz throughput, its functional fragility persists. The Morris–Lecar model captures
Logan Larsh +3 more
wiley +1 more source
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Axonal shortening and the mechanisms of axonal motility
Cell Motility, 1988AbstractAxons in tissue culture retract and shorten if their tips are detached from the substrate. The shortening reaction of the axon involves contractile forces that also arise during normal axonal motility, elongation, and retraction. We studied shortening in axonal segments isolated from their parent axons by transecting the axon between the growth
E B, George +3 more
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Biological Reviews, 1996
Axons damaged in a peripheral nerve are often able to regenerate from the site of injury along the degenerate distal segment of the nerve to reform functional synapses. Schwann cells play a central role in this process. However, in the adult mammalian central nervous system, from which Schwann cells are absent, axonal regeneration does not progress to ...
J E, Brecknell, J W, Fawcett
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Axons damaged in a peripheral nerve are often able to regenerate from the site of injury along the degenerate distal segment of the nerve to reform functional synapses. Schwann cells play a central role in this process. However, in the adult mammalian central nervous system, from which Schwann cells are absent, axonal regeneration does not progress to ...
J E, Brecknell, J W, Fawcett
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Journal of Neurocytology, 2000
The myosin super family is an extended family of actin-based motor proteins that can be divided into 15-18 structurally distinct classes (Sellers, J. R (2000) Biochemica et Biophysica Acta, 1496, 3-22; Hodge, T. & Cope, M. J. T. V. (2000) Journal of Cell Science, 113, 3353-3354; Berg, J. S., Powell, B. C. & Cheney, R. E. (2001) Molecular Biology of the
P C, Bridgman, L L, Elkin
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The myosin super family is an extended family of actin-based motor proteins that can be divided into 15-18 structurally distinct classes (Sellers, J. R (2000) Biochemica et Biophysica Acta, 1496, 3-22; Hodge, T. & Cope, M. J. T. V. (2000) Journal of Cell Science, 113, 3353-3354; Berg, J. S., Powell, B. C. & Cheney, R. E. (2001) Molecular Biology of the
P C, Bridgman, L L, Elkin
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Science Signaling, 2023
Demyelination by microglia reduces the likelihood of axonal degeneration in a model of cytotoxic T cell–driven myelin perturbation.
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Demyelination by microglia reduces the likelihood of axonal degeneration in a model of cytotoxic T cell–driven myelin perturbation.
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2009
Axon pathfinding is an important process in the development of the nervous system. Models have been developed which describe or attempt to explain various aspects of axon pathfinding, such as axon extension, axon turning, axon guidance, interactions between axons, retinotectal mapping, and the way in which guidance cue patterns are generated in the ...
Mortimer, D., Goodhill, G. J.
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Axon pathfinding is an important process in the development of the nervous system. Models have been developed which describe or attempt to explain various aspects of axon pathfinding, such as axon extension, axon turning, axon guidance, interactions between axons, retinotectal mapping, and the way in which guidance cue patterns are generated in the ...
Mortimer, D., Goodhill, G. J.
openaire +4 more sources