Results 251 to 260 of about 271,417 (354)
Impulse Propagation at the Septal and Commissural Junctions of Crayfish Lateral Giant Axons [PDF]
, 1961 Akira Watanabe, Harry Grundfest
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Neuronal C/EBPβ Shortens the Lifespan via Inactivating NAMPT
Advanced Science, EarlyView.Schematic diagram illustrating the mechanism of shortened lifespan in Thy 1‐C/EBPβ transgenic mice and intervention strategies. Briefly, C/EBPβ/AEP escalation in the aging brain triggers NAMPT fragmentation and NAD+ depletion. Knockout of AEP from Thy 1‐C/EBPβ Tg/Tg mice ameliorates cognitive impairments and elongates the lifespan.
Bowei Li +8 more
wiley +1 more source
Current-Voltage Relations in the Lobster Giant Axon Membrane Under Voltage Clamp Conditions [PDF]
, 1962 Fred J. Julian +2 more
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Advanced Science, EarlyView.Overview of the regulation of intrinsic and extrinsic signals during neurodevelopment. Intrinsic genetic signals from NSCs, in conjunction with cues from microglia and blood vessels, collaboratively regulate the proliferation of NSCs, their fate determination, synaptogenesis, synaptic pruning, neuronal survival, and death, as well as communication ...
Yanyan Wang +4 more
wiley +1 more source
Sodium Fluxes in Internally Dialyzed Squid Axons [PDF]
, 1968 F. J. Brinley, L. J. Mullins
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Advanced Science, EarlyView.New research reveals that oxytocin signaling during the early postnatal period is critical for regulating brain development and social behavior. Selectively suppressing oxytocin neurons by chemogenetic method shows that early—but not late—disruption leads to autism‐like behaviors.
Zi‐Hui Wang +10 more
wiley +1 more source
A Facile Strategy to Restore the Optic Nerve Functionality Using an Injectable Conducting Hydrogel
Advanced Science, EarlyView.An injectable conductive polymer hydrogel from poly (3,4‐ethylenedioxythiophene) (PEDOT) is developed to facilitate the recovery of electrophysiological function in injured optic nerve. The hydrogel can be injected directly at the injury site and spontaneously gel in place.
Changchun Yu +12 more
wiley +1 more source
Membrane Potentials of the Lobster Giant Axon Obtained by Use of the Sucrose-Gap Technique [PDF]
, 1962 Fred J. Julian +2 more
openalex +1 more source
Advanced Science, EarlyView.The molecular recognition of the sugar moiety of GD3 and Gb3 (globotriaosylceramide) derivatives by Siglec‐7 has been thoroughly studied offering insights for cancer diagnostics and therapies. A combination of structural biology techniques, nuclear magnetic resonance (NMR) spectroscopy, physicochemical analysis, and in silico methods suggested that ...
Cristina Di Carluccio +15 more
wiley +1 more source
Improving Adult Vision Through Pathway‐Specific Training in Augmented Reality
Advanced Science, EarlyView.Traditional perceptual training approaches are limited by stimulus specificity, treatment efficacy, and patient compliance. A novel altered reality (AR) method is developed to enhance pathway‐specific functions in human adults while performing everyday activities.
Yige Gao +4 more
wiley +1 more source