Results 71 to 80 of about 311,623 (161)

Gene therapy targeting SARM1 blocks pathological axon degeneration in mice [PDF]

open access: yes, 2019
Axonal degeneration (AxD) following nerve injury, chemotherapy, and in several neurological disorders is an active process driven by SARM1, an injury-activated NADase.
DiAntonio, Aaron   +8 more
core   +1 more source

Scattering approach to diffusion quantifies axonal damage in brain injury [PDF]

open access: yesarXiv
Early diagnosis and noninvasive monitoring of neurological disorders require sensitivity to elusive cellular-level alterations that occur much earlier than volumetric changes observable with the millimeter-resolution of medical imaging modalities. Morphological changes in axons, such as axonal varicosities or beadings, are observed in neurological ...
arxiv  

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