Results 11 to 20 of about 7,278 (228)

Studies on 1-azabicyclo compounds. XXVIII. Synthesis of 1-methyl-perhydroazocin-5-one from pyrrolizidine.

open access: bronzeChemical and Pharmaceutical Bulletin, 1979
Heating of pyrrolizidine N-oxide (V) with an aqueous solution of tartaric acid containing ferric nitrate gave Δ1 (8)-dehydropyrrolizidine (VI), which, on treatment with water in the presence of methyl iodide, gave 1-methyl-perhydroazocin-5-one (IX).
Yoshio Arata   +3 more
openalex   +3 more sources

Functional Activity of Enantiomeric Oximes and Diastereomeric Amines and Cyano Substituents at C9 in 3-Hydroxy-N-phenethyl-5-phenylmorphans [PDF]

open access: yesMolecules
The synthesis of stereochemically pure oximes, amines, saturated and unsaturated cyanomethyl compounds, and methylaminomethyl compounds at the C9 position in 3-hydroxy-N-phenethyl-5-phenylmorphans provided μ-opioid receptor (MOR) agonists with varied ...
Hudson G. Roth   +8 more
doaj   +2 more sources

Studies on 1-azabicyclo compounds. XXII. Stereochemistry of 9a-substituted quinolizidine methiodides.

open access: bronzeChemical and Pharmaceutical Bulletin, 1975
Yoshio Arata   +3 more
openalex   +3 more sources

Synthesis and Antiprotozoal Activity of Azabicyclo-Nonane Pyrimidine Hybrids

open access: yesMolecules, 2022
2,4-Diaminopyrimidines and (dialkylamino)azabicyclo-nonanes possess activity against protozoan parasites. A series of fused hybrids were synthesized and tested in vitro against pathogens of malaria tropica and sleeping sickness.
Clemens Hinteregger   +6 more
doaj   +1 more source

Base-Promoted Intramolecular Addition of Vinyl Cyclopropanecarboxamides to Access Conformationally Restricted Aza[3.1.0]bicycles

open access: yesMolecules, 2023
3-Azabicyclo[3.1.0]hexanes are common structural components in natural products and bioactive compounds. Traditionally, the metal-mediated cyclopropanation domino reaction of chain enzymes is the most commonly used strategy for the construction of this ...
Jingya Li   +5 more
doaj   +1 more source

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