Results 11 to 20 of about 911 (193)
Core Steps to the Azaphilone Family of Fungal Natural Products [PDF]
ChemBioChem, Volume 22, Issue 21, Page 3027-3036, November 3, 2021., 2021 Azaphilones are a polyketide‐based family of fungal natural products with a highly oxygenated bicyclic pyrone‐quinone structure, many of which have useful and interesting bioactivities. This minireview reveals the common steps in azaphilone biosynthetic pathways to aid the use of genome mining to identify orphan azaphilone biosynthetic gene clusters ...
Katherine Williams +3 more
wiley +8 more sources
Recent Findings in Azaphilone Pigments [PDF]
Journal of Fungi, 2021 Filamentous fungi are known to biosynthesize an extraordinary range of azaphilones pigments with structural diversity and advantages over vegetal-derived colored natural products such agile and simple cultivation in the lab, acceptance of low-cost ...
Lúcia P. S. Pimenta +3 more
doaj +5 more sources
Substrate-Selective Catalysis Enabled Synthesis of Azaphilone Natural Products [PDF]
ACS Central Science, 2023 Achieving substrate-selectivity is a central element of nature's approach to synthesis. By relying on the ability of a catalyst to discriminate between components in a mixture, control can be exerted over which molecules will move forward in a synthesis.
Ye Wang +4 more
doaj +6 more sources
Azaphilones Pigments from the Fungus Penicillium hirayamae
Colorants, 2023 The use of fungal pigments as dyes is attractive for various industries. Fungal pigments arise a strong interest because they are suitable for large-scale industrial production and have none of the drawbacks of synthetic pigments.
Coralie Pavesi +8 more
doaj +4 more sources
Chemoenzymatic Synthesis of Azaphilone Natural Products [PDF]
, 2021 Over the course of evolution, Nature has crafted innumerous enzymatic machines, capable of great feats of chemistry, across nearly all walks of life. These biocatalysts can construct complex molecular scaffolds, demonstrated by the abundance of intricate natural products isolated from producing organisms.
Pyser, Joshua
openaire +3 more sources
Microorganisms, 2020 Many species of Talaromyces of marine origin could be considered as non-toxigenic fungal cell factory. Some strains could produce water-soluble active biopigments in submerged cultures.
Juliana Lebeau +4 more
doaj +2 more sources
Stereodivergent, Chemoenzymatic Synthesis of Azaphilone Natural Products
Journal of the American Chemical Society, 2019 Selective access to a targeted isomer is often critical in the synthesis of biologically active molecules. Whereas small-molecule reagents and catalysts often act with anticipated site- and stereoselectivity, this predictability does not extend to enzymes.
Joshua B. Pyser +6 more
core +5 more sources
Marine Drugs, 2019 Three new azaphilone alkaloids containing glutamine residues, namely N-glutarylchaetoviridins A−C (1−3), together with two related compounds (4 and 5) were isolated from the extract of Chaetomium globosum HDN151398, a fungus isolated from a ...
Chunxiao Sun +10 more
doaj +2 more sources
European Journal of Organic Chemistry, Volume 2021, Issue 36, Page 5094-5103, September 24, 2021., 2021 Rubiginosins Z‐W, novel azaphilone pigments from stromata of Hypoxylon rubiginosum and H. texense, were isolated. Extensive HRMS, NMR, and ECD analysis revealed their stereochemistry and yielded missing configurations of known congeners. Unlike the related H. fragiforme, H. rubiginosum and H.
Kevin Becker +3 more
wiley +3 more sources
Azaphilones from the Red Sea Fungus Aspergillus falconensis [PDF]
Marine Drugs, 2020 The marine-derived fungus Aspergillus falconensis, isolated from sediment collected from the Canyon at Dahab, Red Sea, yielded two new chlorinated azaphilones, falconensins O and P (1 and 2) in addition to four known azaphilone derivatives (3−6 ...
Dina H. El-Kashef +9 more
doaj +4 more sources