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Shaping Antimalarials: A Geometry-First Approach to <i>Pf</i>CLK3 Covalent Inhibitors. [PDF]

open access: yesJ Med Chem
Brettell SB   +9 more
europepmc   +1 more source

Harnessing Oxetane and Azetidine Sulfonyl Fluorides for Opportunities in Drug Discovery. [PDF]

open access: yesJ Am Chem Soc
Symes OL   +15 more
europepmc   +1 more source
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Novel antibacterial azetidine lincosamides

Bioorganic and Medicinal Chemistry Letters, 2008
The synthesis and evaluation of novel azetidine lincosamides 1 are described. Eleven new (3-trans-alkyl)azetidine-2-carboxylic acids were synthesized via alkylation of N-TBS-4-oxo-azetidine-2-carboxylic acid and subsequent elaboration then coupled to 7-chloro-1-methylthio-lincosamine.
Mikhail F Gordeev
exaly   +3 more sources

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