Results 61 to 70 of about 5,133 (208)
3,3-Dinitroazetidinium 2-hydroxybenzoate
In the title gem-dinitroazetidinium 2-hydroxybenzoate salt, C3H6N3O4+·C7H5O3−, the azetidine ring is virtually planar, with a mean deviation from the plane of 0.0242 Å. The dihedral angle between the two nitro groups
Rong Gao +4 more
doaj +1 more source
Synthetic Strategies for the Construction of Cyclobutane‐Fused Heterocycles
Cyclobutane‐fused heterocycles are important motifs commonly present in bioactive compounds, recognized for their rigid 3D structures that confer unique properties. However, synthesizing these compounds remains challenging. This review discusses current methods for their synthesis, such as photochemical, metal‐catalyzed, and Lewis acid‐mediated [2 + 2]
Michela Vargiu +2 more
wiley +1 more source
4-amino-1,8-naphthalimide azetidine fluorescent indicators and cellular imaging agents
Three 4-amino-1,8-naphthalimides appended with azetidine and substituted at the imide position with methyl 1, dimethylaminoethylene 2 and methyleneferrocene 3 were synthesised.
Alex D. Johnson +3 more
doaj +1 more source
MONDE·T: A database and interactive webserver for non‐standard amino acids and peptide components in the PDB [PDF]
Abstract Non‐standard amino acids (ncAAs) together with synthetic additions (like caps and linkers) are of wide interest for protein design and pharmaceutical optimization, as they can improve physicochemical properties and possibly reshape protein structure. Their inclusion in experimental structures has not been explored systematically.
Waldherr A, Freimann G, Lupas A.
europepmc +2 more sources
Visible‐Light‐Mediated Lewis Acid‐Catalyzed Diradical Hydrogen Atom Transfer Reaction of Enamides
The Lewis acid catalysis was crucial for the success of the DHAT reaction of enamides by lowering the energy of the triplet excited state and modulating the reactivity of the formed diradical intermediate in a carbon‐to‐carbon 1,5‐DHAT and consequent cyclization that allows the functionalization of C(sp3)−H bonds to construct a variety of novel β ...
Yao Huang +5 more
wiley +1 more source
Double Isomerization of Oxetane Amides to Azetidine Esters with Ring Expansion and Contraction
Double Isomerization of Oxetane Amides to Azetidine Esters with Ring Expansion and ...
Toshiyuki Tanaka (1636) +6 more
core +1 more source
L-Azetidine-2-carboxylic acid (AZE) is a non-protein amino acid that shares structural similarities with its proteogenic L-proline amino acid counterpart. For this reason, AZE can be misincorporated in place of L-proline, contributing to AZE toxicity. In
Alessandro Castorina (690336) +8 more
core
Ring opening of photogenerated azetidinols as a strategy for the synthesis of aminodioxolanes
α-Aminoacetophenones are identified as promising building blocks for the synthesis of highly substituted dioxolanes. The presented strategy is founded on the build and release of molecular strain and achieves a formal transposition of a methyl group ...
Henning Maag +2 more
doaj +1 more source
Non-proteinogenic (np) amino acids in the food chain present challenges for the human translation machinery. Here the authors show that, while AlaRS and ProRS activate toxic np azetidine-2-carboxylic acid (Aze) present in sugar beets and lilies, only the
Youngzee Song +10 more
doaj +1 more source
N-[4-(Azetidin-1-ylsulfonyl)phenyl]-N-(2,4-difluorobenzyl)acetamide
In the title molecule, C18H18F2N2O3S, the dihedral angle between the benzene rings is 79.40 (11)°. The 2,4-difluorobenzyl and azetidine fragments adopt a trans arrangement relative to the central benzene ring.
Jian-Mei Lin, Jia-Wen Li, Jing-Song Lv
doaj +1 more source

