Results 61 to 70 of about 5,133 (208)

3,3-Dinitroazetidinium 2-hydroxybenzoate

open access: yesActa Crystallographica Section E, 2010
In the title gem-dinitroazetidinium 2-hydroxybenzoate salt, C3H6N3O4+·C7H5O3−, the azetidine ring is virtually planar, with a mean deviation from the plane of 0.0242 Å. The dihedral angle between the two nitro groups
Rong Gao   +4 more
doaj   +1 more source

Synthetic Strategies for the Construction of Cyclobutane‐Fused Heterocycles

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 40, 27 October 2026.
Cyclobutane‐fused heterocycles are important motifs commonly present in bioactive compounds, recognized for their rigid 3D structures that confer unique properties. However, synthesizing these compounds remains challenging. This review discusses current methods for their synthesis, such as photochemical, metal‐catalyzed, and Lewis acid‐mediated [2 + 2]
Michela Vargiu   +2 more
wiley   +1 more source

4-amino-1,8-naphthalimide azetidine fluorescent indicators and cellular imaging agents

open access: yesResults in Chemistry
Three 4-amino-1,8-naphthalimides appended with azetidine and substituted at the imide position with methyl 1, dimethylaminoethylene 2 and methyleneferrocene 3 were synthesised.
Alex D. Johnson   +3 more
doaj   +1 more source

MONDE·T: A database and interactive webserver for non‐standard amino acids and peptide components in the PDB [PDF]

open access: yesProtein Sci
Abstract Non‐standard amino acids (ncAAs) together with synthetic additions (like caps and linkers) are of wide interest for protein design and pharmaceutical optimization, as they can improve physicochemical properties and possibly reshape protein structure. Their inclusion in experimental structures has not been explored systematically.
Waldherr A, Freimann G, Lupas A.
europepmc   +2 more sources

Visible‐Light‐Mediated Lewis Acid‐Catalyzed Diradical Hydrogen Atom Transfer Reaction of Enamides

open access: yesAdvanced Science, Volume 13, Issue 59, 23 October 2026.
The Lewis acid catalysis was crucial for the success of the DHAT reaction of enamides by lowering the energy of the triplet excited state and modulating the reactivity of the formed diradical intermediate in a carbon‐to‐carbon 1,5‐DHAT and consequent cyclization that allows the functionalization of C(sp3)−H bonds to construct a variety of novel β ...
Yao Huang   +5 more
wiley   +1 more source

Double Isomerization of Oxetane Amides to Azetidine Esters with Ring Expansion and Contraction

open access: yes, 2016
Double Isomerization of Oxetane Amides to Azetidine Esters with Ring Expansion and ...
Toshiyuki Tanaka (1636)   +6 more
core   +1 more source

L-Proline Prevents Endoplasmic Reticulum Stress in Microglial Cells Exposed to L-azetidine-2-carboxylic Acid

open access: yes, 2023
L-Azetidine-2-carboxylic acid (AZE) is a non-protein amino acid that shares structural similarities with its proteogenic L-proline amino acid counterpart. For this reason, AZE can be misincorporated in place of L-proline, contributing to AZE toxicity. In
Alessandro Castorina (690336)   +8 more
core  

Ring opening of photogenerated azetidinols as a strategy for the synthesis of aminodioxolanes

open access: yesBeilstein Journal of Organic Chemistry
α-Aminoacetophenones are identified as promising building blocks for the synthesis of highly substituted dioxolanes. The presented strategy is founded on the build and release of molecular strain and achieves a formal transposition of a methyl group ...
Henning Maag   +2 more
doaj   +1 more source

Double mimicry evades tRNA synthetase editing by toxic vegetable-sourced non-proteinogenic amino acid

open access: yesNature Communications, 2017
Non-proteinogenic (np) amino acids in the food chain present challenges for the human translation machinery. Here the authors show that, while AlaRS and ProRS activate toxic np azetidine-2-carboxylic acid (Aze) present in sugar beets and lilies, only the
Youngzee Song   +10 more
doaj   +1 more source

N-[4-(Azetidin-1-ylsulfonyl)phenyl]-N-(2,4-difluorobenzyl)acetamide

open access: yesActa Crystallographica Section E, 2012
In the title molecule, C18H18F2N2O3S, the dihedral angle between the benzene rings is 79.40 (11)°. The 2,4-difluorobenzyl and azetidine fragments adopt a trans arrangement relative to the central benzene ring.
Jian-Mei Lin, Jia-Wen Li, Jing-Song Lv
doaj   +1 more source

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