Results 71 to 80 of about 5,133 (208)

Selective Photoinduced α‐Amino C(sp3)–H Alkylation Mediated by NHC–Borane

Advanced Synthesis &Catalysis, Volume 368, Issue 17, 1 September 2026.
Herein, we report a selective photoinduced functionalization of α‐amino C(sp3)─H bonds mediated by NHC–boranes. This reaction proceeds efficiently without the need for any external radical initiator or photoredox catalyst. Mechanistic studies reveal that the reaction proceeds via an efficient radical chain, featuring the formation of an aryl radical ...
Gabin Lalande, Laurent Chabaud, Mathieu Pucheault   +2 more
wiley   +1 more source

Synthesis and Structure of Novel Conformationally Constrained 1‘,2‘-Azetidine-Fused Bicyclic Pyrimidine Nucleosides:  Their Incorporation into Oligo-DNAs and Thermal Stability of the Heteroduplexes

, 2016
The synthesis of novel 1‘,2‘-aminomethylene bridged (6-aza-2-oxabicyclo[3.2.0]heptane) “azetidine” pyrimidine nucleosides and their transformations to the corresponding phosphoramidite building blocks (20, 39, and 42) for automated solid-phase ...
Jharna Barman (2485954), Jyoti Chattopadhyaya (1695679), Oommen P. Varghese (1938592), Oleksandr Plashkevych (1695667), Dmytro Honcharenko (723394)   +4 more
core   +1 more source

N-Benzyl-1,3-dideoxy-1,3-imino-l-xylitol

Acta Crystallographica Section E, 2011
The structure determination confirms the stereochemistry of the title compound, C12H17NO3, which contains a four-membered azetidine ring system. The absolute configuration was determined by the use of d-glucose as the starting material. In the crystal, O&
Sarah F. Jenkinson, Gabriel M. J. Lenagh-Snow, George W. J. Fleet, Amber L. Thompson   +3 more
doaj   +1 more source

Cerium Nanoparticle‐Mediated Inhibition of the NSUN2/m5C Axis Suppresses Synovial Aggression in Rheumatoid Arthritis

Advanced Science, Volume 13, Issue 54, 28 September 2026.
A novel epitranscriptomic mechanism in rheumatoid arthritis is uncovered: NSUN2 promotes disease via m5C‐dependent stabilization of ICMT mRNA, fueling the migration and invasion of pathogenic RA FLS. Targeting this axis with engineered nanoparticles (Ce/SAA NPs) effectively inhibits disease progression, presenting a precise therapeutic strategy ...
Ruiru Li, Simin Chen, Huijuan Hu, Shiyao Wu, Jingnan Wang, Kai Sun, Chenxi Peng, Suling Liu, Shuoyang Zhang, Yu Kuang, Wei Chen, Qian Qiu, Liuqin Liang, Yu Wen, Hanshi Xu, Youjun Xiao   +15 more
wiley   +1 more source

Organocatalytic Access to Enantioenriched Spirooxindole-Based 4-Methyleneazetidines

Molecules, 2017
This work describes the synthesis of enantioenriched spiro compounds, incorporating the azetidine and the oxindole motifs. The preparation relies on a formal [2 + 2] annulation reaction of isatin-derived N-tert-butylsulfonyl ketimines with allenoates ...
Giulia Rainoldi, Matteo Faltracco, Claudia Spatti, Alessandra Silvani, Giordano Lesma   +4 more
doaj   +1 more source

Synthesis and Rapid Polymerizations of Aryl- and Alkyl-bis(azetidine-2,4-dione)s to Polymalonamide Elastomers

, 2014
Two new synthetic methodologies for making aryl- and alkyl-bis(azetidine-2,4-dione)s have been accomplished in this study. A new family of N,N'-benzophenonyl bis(azetidine-2,4-dione)s (2) has been successfully synthesized through autoxidation of readily ...
Kuo, M.C., Jeng, R.J., 戴憲弘, 鄭如忠, Tung, Y.C., Dai, S.A., Yeh, C.L., Chang, H.Y.   +7 more
core   +1 more source

Study of boron-nitrogen dative bonds using azetidine inversion dynamics

, 2013
Study of boron-nitrogen dative bonds using azetidine inversion ...
M Rowland (11802449), Tiffany Walsh (13097721), J Tucker (13688752), M Shipman (13661443), G Clarkson (13713937), C Hoang (13713931), I Prokes (13713934)   +6 more
core  

Synthesis and Rapid Polymerizations of Aryl- and Alkyl-bis(azetidine-2,4-dione)s to Polymalonamide Elastomers

, 2016
Two new synthetic methodologies for making aryl- and alkyl-bis(azetidine-2,4-dione)s have been accomplished in this study. A new family of N,N′-benzophenonyl bis(azetidine-2,4-dione)s (2) has been successfully synthesized through autoxidation of readily ...
Ming-Chieh Kuo (2066752), Hsin-Yu Chang (289835), Ru-Jong Jeng (1418647), Yen-Chen Tung (2401948), Chung-Lun Yeh (2401945), Shenghong A. Dai (2041018)   +5 more
core   +1 more source

The effect of azetidine-2-carboxylic acid on proline biosynthesis in Escherichia coli [PDF]

The effect of the proline analogue, L-azetidine-2-carboxylic acid, on proline biosynthesis in Escherichia coli has been studied. The analogue inhibits the formation of proline precursor by acting as a false feedback inhibitor, Analysis of kinetic ...
Smith, Faith Irene
core   +5 more sources

Synthesis, Computational Studies, and Structural Analysis of 1-(3,5-Dimethoxyphenyl)azetidin-2-ones with Antiproliferative Activity in Breast Cancer and Chemoresistant Colon Cancer

Pharmaceuticals
Background/Objectives: A series of 1-(3,5-dimethoxyphenyl)azetidine-2-ones were synthesised to evaluate their antiproliferative activity in MCF-7 breast cancer cells and HT-29 chemoresistant colon cancer cells. The 1,4-diarylazetidin-2-ones were designed
Azizah M. Malebari, Shubhangi Kandwal, Abdirahman Ali, Darren Fayne, Brendan Twamley, Daniela M. Zisterer, Mary J. Meegan   +6 more
doaj   +1 more source