Results 91 to 100 of about 2,792 (191)
Synthesis of 1,3-Disubstituted Azetidines via a Tandem Ring-Opening Ring-Closing Procedure
The synthesis of N-substituted symmetrical azetidines has been achieved in high yields via the reaction of primary amines undergoing an epoxide ring-opening reaction followed by an in situ ring-closing step.
Turner, Nicholas J.; id_orcid +4 more
core +1 more source
Pyrrolidinones can be synthesized in high yields and regioselectivity by the cobalt carbonyl catalyzed carbonylation of azetidines. For 2-substituted azetidines (alkyl, aryl, CH2OH, CH2OR, CH2OCOR, and COOR), carbonyl insertion occurs in the more or less
D. ROBERTO, H. ALPER
core +1 more source
Reaction of Azetidines with Chloroformates
The reaction of an azetidine with a chloroformate can give either the dealkylated heterocycle or the ring-opened product (γ-chloroamine), which can further cyclize to the oxazinanone. A general study of this underrated reaction was conducted and revealed
Gwilherm Evano (1355874) +3 more
core +1 more source
Editorial: Strained Aza-Heterocycles in Synthesis
Hyun-Joon Ha
doaj +1 more source
An Efficient Synthesis of Azetidines with (2-Bromoethyl)sulfonium Triflate
Easily accessible arylglycine derivatives were cyclized to azetidines by using commercially available (2-bromoethyl)sulfonium triflate in a simple and mild procedure.
Moya, Juan F. +4 more
core +1 more source
Iron- and cobalt-catalyzed cross-couplings between iodo-azetidines, -pyrrolidines, -piperidines, and Grignard reagents are disclosed. The reaction is efficient, cheap, chemoselective and tolerates a large variety of (hetero)aryl Grignard ...
Sébastien Reymond (1710181) +8 more
core +1 more source
Modular synthesis of functionalized azetidines through visible-light copper-catalyzed carboamination of 1,3-dienes with azabicyclo[1.1.0]butanes. [PDF]
Koo Y, Lee D, Park J, Hong S.
europepmc +1 more source
Strain Release of 1-Azabicyclo[1.1.0]butanes as a Gateway to Highly Functionalized Azetidines: New Strategies and Structural Motifs. [PDF]
Gelato Y, Natho P, Colella M, Luisi R.
europepmc +1 more source
Lewis Acid Catalyzed Dual Strain-Release Platform for Transforming Azabicyclo[1.1.0]butanes into Functionalized Azetidines with Donor-Acceptor(D-A) Cyclopropanes and Bicyclo[1.1.0]butanes. [PDF]
Hazra S +6 more
europepmc +1 more source

