Results 221 to 230 of about 8,323 (256)

Synthesis of highly functionalized homochiral azetidines and azetidine-2-carboxylic esters

Tetrahedron, 1993
Abstract Homochiral (2S, 3S)-3-benzyloxy-2-formyl-azetidines 2, (2S, 3S)-3-benzyloxy-2-carbomethoxy-azetidines 3 and the highly strained (2S)-N-p-methoxyphenyl-2-silyloxymethyl-3-azetidinone 4 were successfully synthesized starting from diethyl-L-tartrate.
Annie Duréault, Martine Portal, François Carreaux, Jean Claude Depezay   +3 more
openaire   +1 more source

Novel Syntheses of Azetidines and Azetidinones

Chemical Reviews, 2008
2.1.5. Electrophilic Attack on CdC 3994 2.1.6. NH Insertions in Diazo Compounds 3994 2.1.7. Pd Catalyzed Cyclizations 3994 2.2. Cyclizations by C-C Bond formation 3995 2.2.1. Nucleophilic Displacement of Halides 3995 2.2.2. Cyclizations Involving CdO Group 3995 2.3. Cycloadditions 3996 2.4. Ring Rearrangements 3997 2.4.1.
BRANDI, ALBERTO, CICCHI, STEFANO, CORDERO, FRANCA MARIA   +2 more
openaire   +2 more sources

The renaissance of strained 1-azabicyclo[1.1.0]butanes as useful reagents for the synthesis of functionalized azetidines.

Organic and biomolecular chemistry, 2020
Since their discovery in the late 1960s, 1-azabicyclo[1.1.0]butanes have demonstrated to be interesting precursors of azetidines, because of the peculiar reactivity of the C3-N bond that allows double functionalization in the 1,3 positions. In particular,
Michael Andresini, L. Degennaro, R. Luisi   +2 more
semanticscholar   +1 more source

A convenient synthesis of azetidine-2-thiones and azetidin-2-imines

Journal of the Chemical Society, Chemical Communications, 1983
Azetidin-2-iminium salts, which are readily available from tertiary amides, can be easily converted into the corresponding thiones or imines.
Jacqueline Marchand-Brynaert, Manuel Moya-Portuguez, Isabelle Huber, L�on Ghosez   +3 more
openaire   +1 more source

Amino acid–azetidine chimeras: synthesis of enantiopure 3‐substituted azetidine‐2‐carboxylic acids

The Journal of Peptide Research, 2005
Abstract:  Azetidine‐2‐carboxylic acid (Aze) analogs possessing various heteroatomic side chains at the 3‐position have been synthesized by modification of 1‐9‐(9‐phenylfluorenyl) (PhF)‐3‐allyl‐Aze tert‐butyl ester (2S,3S)‐1. 3‐Allyl‐Aze 1 was synthesized by regioselective allylation of α‐tert‐butyl β‐methyl N‐(PhF)aspartate 13, followed by selective ω‐
Z, Sajjadi, W D, Lubell
openaire   +2 more sources

Synthesis of 3-Aryl-3-Sulfanyl Azetidines by Iron-Catalyzed Thiol Alkylation with N-Cbz Azetidinols.

Journal of Organic Chemistry, 2019
New small-ring derivatives can provide valuable motifs in new chemical space for drug design. 3-Aryl-3-sulfanyl azetidines are synthesized directly from azetidine-3-ols in excellent yield by a mild Fe-catalyzed thiol alkylation.
Maryne A. J. Dubois, A. Lazaridou, Chulho Choi, J. Mousseau, J. Bull   +4 more
semanticscholar   +1 more source

Mass spectra of azetidines

Organic Mass Spectrometry, 1972
AbstractThe mass spectra of azetidine, 2‐methylazetidine, 2‐phenylazetidine, methylene‐bis‐azetidines, their N‐halo‐ and N‐tosyl derivatives, 2‐phenylazetine as well as N,N‐dimethylmethane sulphonamide, N,N‐dimethyl and N,N‐diethyl‐ p‐toluene sulphonamides have been investigated.
R. G. Kostyanovsky, V. I. Markov, I. M. Gella, Kh. Khafizov, V. G. Plekhanov   +4 more
openaire   +1 more source

Minisci-Photoredox-Mediated α-Heteroarylation of N-Protected Secondary Amines: Remarkable Selectivity of Azetidines.

Organic Letters, 2018
The development of a general, mild, and functional-group-tolerant direct functionalization of N-heteroarenes by C-H functionalization with N-protected amines, including azetidines under Minisci-mediated photoredox conditions, is reported.
C. Bosset, H. Beucher, Guillaume Bretel, E. Pasquier, Laurence Quéguiner, C. Henry, Ann Vos, J. Edwards, L. Meerpoel, Didier Berthelot   +9 more
semanticscholar   +1 more source

Azetidines

2021
Jie Jack Li, Minmin Yang
openaire   +1 more source

Synthesis of Azetidine from 1-Substituted Azetidin-3-ols

HETEROCYCLES, 1986
Yoshihiro Nitta, Yasuyuki Kanamori
openaire   +1 more source