Results 161 to 170 of about 132,389 (268)

Targeting DNA‐LNPs to Endothelial Cells Improves Expression Magnitude, Duration, and Specificity

Advanced Science, EarlyView.
Attaching antibodies against endothelial cell surface proteins redirects the delivery and expression of DNA‐lipid nanoparticles to organs of interest. Our targeted nanoparticles enable organ‐selective DNA expression in the endothelium of the lungs, brain, or spleen, providing a therapeutic platform for dozens of endothelial‐centric diseases.
Nicolas Marzolini, Taylor V. Brysgel, Ryan J. Rahman, Eno‐Obong Essien, Saw Y. Nwe, Jichuan Wu, Aparajeeta Majumder, Manthan N. Patel, Sachchidanand Tiwari, Carolann L. Espy, Fengyi Dong, Sabrina A. Santos‐De León, Anit Shah, Vladimir V. Shuvaev, Elizabeth D. Hood, Liam S. Chase, Drew Weissman, Jeremy B. Katzen, David B. Frank, Mariko L. Bennett, Oscar A. Marcos‐Contreras, Jacob W. Myerson, Vladimir R. Muzykantov, Sahily Reyes‐Esteves, Jacob S. Brenner   +24 more
wiley   +1 more source

A hydroxyl group dictates handedness, pitch, and mechanics in a crystalline covalent helical polymer. [PDF]

Sci Adv
Khazeber R, Xavier D, Sureshan KM.
europepmc   +1 more source

Mutagenic Effects of Sodium Azide and Diethyl Sulphate on the Growth of Leucaena Trees (Leucaena leucocephala Lam.) Under Field Conditions [PDF]

, 2015
Yasser I. El-Nasha, Nader D. Shetta
openalex   +1 more source

Sabatier‐Adjusted d‐Band Centers of Scalable Asymmetric Iron Sites toward Dynamic Nonradical Network for Fast Mineralization with Low‐Amount Oxidant

Advanced Science, EarlyView.
Asymmetric iron single‐atom catalysts with Sabatier‐adjusted d‐band centers overcome the inherent limitations of peroxymonosulfate (PMS) activation by establishing a synergistic nonradical pathway network, achieving exceptional pollutant mineralization (≈85%) at only one‐tenth conventional PMS dosage.
Yue Chen, Xunheng Jiang, Zhiyu Pan, Zhenjie Li, Chaohuang Chen, Can Li, Chenghui Luo, Shengkun Zhang, Daohui Lin, Xinhua Xu, Jiang Xu   +10 more
wiley   +1 more source

Bioorthogonal Chemistry in Biomolecule Quantification: A Review of Reactions and Strategies. [PDF]

Chemistry
Yang M, Wang S.
europepmc   +1 more source

Core Fucosylation Represses SMURF1‐Dependent Degradation of CD47 to Promote Tumor Immune Evasion

Advanced Science, EarlyView.
FUT8‐mediated core fucosylation of CD47 at N111 blocks SMURF1 binding and reduces CD47 ubiquitination and degradation. Blocking N111 glycosylation reduces CD47 expression and promotes macrophage phagocytosis of tumor cells. Furthermore, ablating CD47 core fucosylation boosts CD103+ dendritic cells (DCs) infiltration, increases natural killer (NK) cell ...
Yuting Cao, Siyuan Chai, Mingyang Li, Xiaoming Chen, Jiating Hu, Bingyi Lin, Liming Wu, Wen Yi, Qiang Zhu   +8 more
wiley   +1 more source

High-valent sulfur fluorides as reactivity switches for PFAS-free benzene-azepine skeletal editing. [PDF]

Chem Sci
Nagababu C, Muramatsu T, Bacho MZ, Wu S, Ochiai S, Escorihuela J, Shibata N.   +6 more
europepmc   +1 more source

Colour centres in alkali metal azides

, 2012
J. P. S. Pringle
openalex   +1 more source

KINETICS AND MECHANISM OF THE CURTIUS REARRANGEMENT OF m-NITROBENZOYL AZIDE IN AQUEOUS SOLUTIONS OF SULFURIC ACID

, 2022
Yuliya N. Pavlyukova, Natalija V. Kudryavtseva, В. А. Островский   +2 more
openalex   +1 more source

Magnetic Resonance Imaging Reveals Meningeal Lymphatic Impairment in Lung Adenocarcinoma Brain Metastasis Progression

Advanced Science, EarlyView.
This study demonstrates meningeal lymphatic impairment associated with lung adenocarcinoma brain metastasis progression in both human patients and mouse models, establishes clinically applicable non‐invasive imaging biomarkers for quantitative analyzing mLV structure and function, and reveals mLVs as robust prognostic indicators and promising potential
Yuan Zhang, Shucheng Jin, Penghui Guo, Yuying Yin, Yichun Hua, Xiaosheng Ding, Zhe Zhang, Shuo Chen, Xu Han, Baowang Li, Yan Liu, Xiaoyan Li, Deling Li, Jing Jing, Wei Shi, Wang Jia   +15 more
wiley   +1 more source