Results 231 to 240 of about 152,508 (309)

Design rules for bioorthogonal glycan-based tools. [PDF]

open access: yesBiochem J
Hoddle F   +3 more
europepmc   +1 more source

Polyproline: A Synthetic Polypeptide With Unique Properties

open access: yesAngewandte Chemie, EarlyView.
Poly‐L‐proline is a unique polypeptide distinguished by its well‐defined secondary structures and unusual thermal behavior. This mini review highlights recent advances in the synthesis of poly‐L‐proline by N‐carboxyanhydride (NCA) polymerization, the formation of structurally defined architectures and nanostructures, and emerging strategies that ...
Rosanna Le Scouarnec   +3 more
wiley   +1 more source

Should I Stay or Should I Go—Leveraging an Overlooked Feature of Click‐to‐Release Chemistry for Affinity Labeling

open access: yesAngewandte Chemie, EarlyView.
Click‐to‐release (C2R) chemistry is redirected from payload liberation toward ligand‐directed covalent protein labeling through a transient dihydropyridazine methide (DHP‐methide). This concept opens the way to dual‐functional systems combining covalent target engagement with controlled effector release.
Dóra Kern   +9 more
wiley   +1 more source

Orthogonal Triple-Click Synthesis of Heteromimetic Triglycosylated Fullerenes. [PDF]

open access: yesOrg Lett
Nieto-Ortiz G   +5 more
europepmc   +1 more source

Chemical Switching Between B2N and B2C Homoaromaticity

open access: yesAngewandte Chemie, EarlyView.
We report the synthesis of homoaromatic 1‐aza‐2,4‐diazadiboretane with a bicyclic four‐membered NB2C motif and demonstrate experimentally and theoretically that the homoaromatic delocalization can also be chemically shifted from the B2N to the B2C moiety by deprotonation of the ring carbon atom.
Tim Wiesmeier   +5 more
wiley   +1 more source

Active Templating by Mechanochemistry. [PDF]

open access: yesOrg Lett
Evans ON, Belenguer AM, Hunter CA.
europepmc   +1 more source

Biotin‐ and Chloroalkane‐Modified Nucleotides for Dual Display of Proteins on DNA Through Streptavidin and Halotag Binding

open access: yesAngewandte Chemie, EarlyView.
Modified 2’‐deoxy‐7‐deazaadenosine bearing a chlorohexyl moiety and 2’‐deoxycytidine nucleotides bearing biotin were used in the enzymatic synthesis of dually modified dsDNAs that served as scaffolds for display of halotag and monomeric streptavidin proteins.
Giammarco Liuni   +4 more
wiley   +1 more source

Clicking acylgermanes: modular access to photoinitiators for visible-light photopolymerization.

open access: yesOrg Chem Front
Culum A   +14 more
europepmc   +1 more source

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