Results 241 to 250 of about 227,350 (349)

Tetramethylguanidinium Azide (TMGA) - A Versatile Azidation Agent [PDF]

Synlett, 2008
openaire   +2 more sources

New Transferrin Receptor‐Targeting Conjugate Effectively Delivers DNA to Mouse Brain

Angewandte Chemie, EarlyView.
We present a novel RNA aptamer targeting the transferrin receptor (TfR), conjugated with DSPE lipid, which achieves remarkably efficient brain uptake, reaching brain‐to‐serum ratios as high as 6.5. Through fluorescence imaging and polymerase‐chain reaction analyses, we verify that this new conjugate successfully delivers a substantial amount of DNA ...
Min‐sun Song, Adrian H. Bustos, Lise Bastue, Justas Mikutavicius, Piotr Swiderski, Kelly J. Clemens, Nagy Habib, John Rossi, Kira Astakhova   +8 more
wiley   +1 more source

Not So Bioorthogonal Chemistry. [PDF]

J Am Chem Soc
Schauenburg D, Weil T.
europepmc   +1 more source

Ribozyme‐Catalyzed Site‐Specific Labeling of RNA Using O6‐alkylguanine SNAP‐Tag Substrates

Angewandte Chemie, EarlyView.
SNAPR is a ribozyme that repurposes O6‐benzylguanine SNAP‐tag substrates for site‐specific labeling of RNA with bioorthogonal alkyne and azide functional groups, fluorophores or photocrosslinkers. The N1A‐alkylated RNA products were converted to N6A‐modified RNA by Dimroth rearrangement.
Manisha B. Walunj, Carolin P. M. Scheitl, Tina Jungnickel, Claudia Höbartner   +3 more
wiley   +1 more source

Metabolic activities are selective modulators for individual segmentation clock processes. [PDF]

Nat Commun
Matsuda M, Lázaro J, Ebisuya M.
europepmc   +1 more source

LC‐MS and High‐Throughput Data Processing Solutions for Lipid Metabolic Tracing Using Bioorthogonal Click Chemistry

Angewandte Chemie, EarlyView.
This study introduces an integrated analytical and bioinformatics platform for high‐throughput tracing of lipid metabolism using bioorthogonal alkyne fatty acids and optimized LC‐MS workflow. Applied to human fibrosarcoma cells, the method traced fatty acid metabolism, revealing nuances in sphingolipid routing and metabolic bottlenecks, highlighting ...
Palina Nepachalovich, Stefano Bonciarelli, Gabriele Lombardi Bendoula, Jenny Desantis, Michela Eleuteri, Christoph Thiele, Laura Goracci, Maria Fedorova   +7 more
wiley   +1 more source

Polymeric PEG-based bioorthogonal triggers for prodrug activation in breast cancer. [PDF]

RSC Adv
Mitry MMA, Osborn HMI, Greco F.
europepmc   +1 more source

Electronic Spectra of Thiocyanate, Selenocyanate, and Azide Complexes of Manganese, Vanadium, and Indium

, 1969
Hans‐Herbert Schmidtke, Dieter Garthoff   +1 more
openalex   +2 more sources

Studies in Azides. Part II. Synthesis of Some Substituted 1,2,3-Triazoles [PDF]

, 1963
Daleep Singh Deorha, Vijayendra Kumar Mahesh, Somir Kumar Mukherjee   +2 more
openalex   +1 more source

Supramolecular Gels as Active Tools for Reaction Engineering

Angewandte Chemie, EarlyView.
The unique combination of environments within gels, self‐assembled from low‐molecular‐weight gelators, offers the ability to control reactivity in new ways, achieving unique reaction outcomes, leading to the emerging concept of supramolecular gels as nanoreactors. Smart chemical engineering methods enable the use of such gels to fabricate materials and
David K. Smith
wiley   +1 more source