Results 81 to 90 of about 236,434 (328)

Effect of Nanoparticle Rigidity on the Interaction of Stromal Membrane Particles with Leukemia Cells

Advanced Healthcare Materials, EarlyView.
Cell membrane nanoparticles made with stromal cells are prepared and used to target leukemia cells. Deposition of the cell membrane onto rigid silica cores leads to increased uptake both in leukemia cell lines and primary cells from patients. These results show that nanoparticle rigidity affects the interaction between cell membrane nanoparticles and ...
Sander de Weerd, Xinyu Ma, Zahra Zohali, Lieve L. Oudejans, Emmanouil Kyrloglou, Marc. C. A. Stuart, Wouter H. Roos, Jan Jacob Schuringa, Anna Salvati   +8 more
wiley   +1 more source

Revealing nascent proteomics in signaling pathways and cell differentiation. [PDF]

, 2018
Regulation of gene expression at the level of protein synthesis is a crucial element in driving how the genetic landscape is expressed. However, we are still limited in technologies that can quantitatively capture the immediate proteomic changes that ...
Burlingame, Alma L, Chalkley, Robert J, Forester, Craig M, Oses-Prieto, Juan A, Phillips, Nancy J, Ruggero, Davide, Urisman, Anatoly, Zhang, Li, Zhao, Qian   +8 more
core   +1 more source

Design and Validation of Hybrid Polymer‐Lipid Nanoparticles as Novel Transfection Vectors for MicroRNA Delivery to Human Cardiac Fibroblasts

Advanced Healthcare Materials, EarlyView.
Hybrid NPs are developed as efficient, scalable nanocarriers for in vitro microRNA delivery, ensuring high loading efficiency, controlled release, physiological and long‐term storage stability. They outperform commercial lipid‐based reagents in terms of transfection efficiency and biocompatibility.
Letizia Nicoletti, Camilla Paoletti, Martina Coletto, Elena Marcello, Giovanni Paolo Stola, Francesca Cossetta, Francesco Schiavone, Ilaria Andreana, Barbara Stella, Silvia Arpicco, Clara Mattu, Valeria Chiono   +11 more
wiley   +1 more source

Bis{bis(azido-κN)bis[bis(pyridin-2-yl-κN)amine]cobalt(III)} sulfate dihydrate

Acta Crystallographica Section E: Crystallographic Communications, 2016
The search for new molecular materials with interesting magnetic properties, using the pseudohalide azide ion and di-2-pyridylamine (dpa, C10H9N3) as a chelating ligand, led to the synthesis and structure determination of the title compound, [Co(N3)2(dpa)
Fatima Setifi, Jacqueline M. Knaust, Zouaoui Setifi, Rachid Touzani   +3 more
doaj   +1 more source

Nitrene Transfer Catalyzed by a Non-Heme Iron Enzyme and Enhanced by Non-Native Small-Molecule Cofactors [PDF]

, 2019
Transition-metal catalysis is a powerful tool for the construction of chemical bonds. Here we show that a non-heme iron enzyme can catalyze olefin aziridination and nitrene C–H insertion, and that these activities can be improved by directed evolution ...
Arnold, Frances H., Goldberg, Nathaniel, Knight, Anders M., Zhang, Ruijie   +3 more
core   +1 more source

Biphasic Granular Bioinks for Biofabrication of High Cell Density Constructs for Dermal Regeneration

Advanced Healthcare Materials, EarlyView.
This study introduces a biphasic granular bioink (µInk) that enables 3D bioprinting of high cell density constructs for dermal regeneration. The bioink promotes cell proliferation, ECM deposition, and neovascularization, leading to tissue integration and reduced scar formation in vivo.
Rozalin Shamasha, Sneha Kollenchery Ramanathan, Kristin Oskarsdotter, Fatemeh Rasti Boroojeni, Aleksandra Zielińska, Sajjad Naeimipour, Philip Lifwergren, Nina Reustle, Lauren Roberts, Annika Starkenberg, Gunnar Kratz, Peter Apelgren, Karin Säljö, Jonathan Rakar, Lars Kölby, Daniel Aili, Johan Junker   +16 more
wiley   +1 more source

Ultra‐Tiny Gelatin Nanoparticles‐Assisted 3D Stem Cell Spheroids for Engineering Tissue Regeneration

Advanced Healthcare Materials, EarlyView.
GNPs effectively guide the formation of structurally compact and functionally enhanced stem cell spheroids. This GNP‐assisted 3D culture system improves cell–cell and cell‐ECM interactions, leading to superior viability and complexity. Time‐dependent regenerative potential is demonstrated in both bone and skin defects, positioning GNP‐spheroids as a ...
Dream Kim, Woochan Kim, Harshita Sharma, Shinyull Lee, Chaeyeon Park, Sunho Park, Chan Yeong Heo, Jangho Kim   +7 more
wiley   +1 more source

Salivary Hydrogen Sulfide Measured with a New Highly Sensitive Self-Immolative Coumarin-Based Fluorescent Probe

Molecules, 2018
Ample evidence suggests that H2S is an important biological mediator, produced by endogenous enzymes and microbiota. So far, several techniques including colorimetric methods, electrochemical analysis and sulfide precipitation have been developed for H2S
Ewelina Zaorska, Marek Konop, Ryszard Ostaszewski, Dominik Koszelewski, Marcin Ufnal   +4 more
doaj   +1 more source

Coulometric Determination of Sulphur Compounds Using the Induced lodine-Azide Reaction [PDF]

, 2004
Wydrukowano z dostarczonych Wydawnictwu UŁ gotowych materiałówThe review summarizes application of coulometry for determination of the sulphur compounds that induce the iodine-azide reaction.
Ciesielski, Witold
core  

Site-selective multi-porphyrin attachment enables the formation of a next-generation antibody-based photodynamic therapeutic [PDF]

, 2015
Herein we present a significant step towards next-generation antibody-based photodynamic therapeutics. Site-selective modification of a clinically relevant monoclonal antibody, with a serum-stable linker bearing a strained alkyne, allows for the ...
Boyle, Ross, Bryden, Francesca, Caddick, Stephen, Chudasama, Vijay, Maruani, Antoine, Savoie, Huguette   +5 more
core   +2 more sources