Isolation of a Staudinger-type Intermediate Utilizing a Five-Membered Phosphorus-Centered Biradicaloid. [PDF]
Pilopp Y +3 more
europepmc +1 more source
Silicon‐Based Azo Compound‐Mediated CO Activation and N2 Release
A rare silicon(IV)‐based azo compound featuring a Si─N═N─Si linkage was synthesized via the direct reaction of an organoazide with a silaiminyl–silylene precursor. This compound undergoes an unusual CO activation process, resulting in N2 release and complete cleavage of the C≡O bond, forming a Si(II)/Si(IV) product bridged by an oxygen atom and an ...
Da Jin +3 more
wiley +1 more source
Click-Triggered Bioorthogonal Bond-Cleavage Reactions. [PDF]
Keppel P, Hecko S, Mikula H.
europepmc +1 more source
Modular Synthesis of Pyritide‐Inspired Macrocycles Featuring Bipyridine Motifs
A pyritide‐inspired build/couple/pair strategy yields a diverse macrocycle library. This approach expands chemical space and enables the discovery of 6paW, a potent anti‐ferroptotic agent. Abstract Macrocycles represent a promising class of drug‐like scaffolds with unique structural features and the ability to engage challenging targets such as protein–
Ji Hyae Lee +4 more
wiley +1 more source
eCarbonyls: an electrochemical thioether mediated oxidation of alcohols to aldehydes and ketones. [PDF]
Molloy C +4 more
europepmc +1 more source
A Broadly Applicable Strategy to Aminate Azines Enabled by Electronically Tuned Phosphine Reagents
We have developed a pyridine C4‐amination reaction via phosphonium salt intermediates, where an electronically tuned phosphine is key to successful C─N bond formation. The process accommodates aliphatic amines, (heteroaryl)anilines, hydrazines, and nitrogen heteroaromatics, as well as a variety of pyridine building blocks and late‐stage C─N couplings ...
Ren‐Rong Liu +2 more
wiley +1 more source
Design, synthesis, and antimicrobial evaluation of new triazole-tethered tetrazole hybrids via DNA gyrase inhibition. [PDF]
Agarwal A +4 more
europepmc +1 more source
CYTOLOGICAL EFFECTS OF PCMB, BAL, ISOMYTAL AND SODIUM AZIDE ON HeLa CELLS IN VITRO
KOHTARO YAMAMOTO
openalex +2 more sources
Greening of Monocyclic N- and O‑Azole Synthesis through Sonochemistry. [PDF]
Hoffman GR, Saeed MM, Schoffstall AM.
europepmc +1 more source

