Results 261 to 270 of about 43,569 (363)

Size‐Programmable Matteson‐Type Annulation: Construction of Spirocycles from Simple Cyclic Ketones

open access: yesAngewandte Chemie, EarlyView.
An iterative boron‐homologation approach is developed to enable programmable syntheses of various carbocycles with different sizes stereoselectively from simple precursors. This method utilizes an electron‐withdrawing group (EWG) as a handle to enable intramolecular Matteson‐type couplings, leading to diastereoselective and enantioselective ring ...
Woohyun Jo   +4 more
wiley   +1 more source

Synthesis and reactivity of a parent phosphathioethynolato-borane and a boraarsaketene. [PDF]

open access: yesChem Sci
Jürgensen M   +5 more
europepmc   +1 more source

Low‐Symmetry Face‐Capped Fe(II) Tetrahedra Through Anisotropic Ligand Extension

open access: yesAngewandte Chemie, EarlyView.
A strategy for the formation of low‐symmetry face‐capped Fe(II) tetrahedra using anisotropic ligand extension is reported. The degree of distortion in the resulting tetrahedra correlates to the stability of the assemblies and the oxidation potentials of their metal ions. Abstract Low‐symmetry cages are attractive metallo‐supramolecular targets, as they
Jacob A. Gome   +7 more
wiley   +1 more source

Unnatural Triggers Converted From Tetrazine‐Attached Sialic Acid for Activation of Optoacoustic Imaging‐Guided Cancer Theranostics

open access: yesAngewandte Chemie, EarlyView.
Tetrazine precursors (SiaTz) based on a nonO‐acetylated sialic acid scaffold are rationally designed and synthesized, which can be efficiently converted into unnatural tetrazine (Tz) triggers on cancer cell surfaces via metabolic glycoengineering. These Tz triggers activate theranostic agents for multispectral optoacoustic tomographic (MSOT) imaging ...
Yinglong Wu   +15 more
wiley   +1 more source

Nanoparticle‐Mediated Targeted Protein Degradation: An Emerging Therapeutics Technology

open access: yesAngewandte Chemie, EarlyView.
Targeted protein degradation (TPD) has emerged as a powerful therapeutic approach, with numerous candidates molecules now advancing into clinical development. Recent innovations have incorporated nanoparticles to facilitate and enhance these degradation processes, yielding synergistic effects.
Andrew G. Baker   +3 more
wiley   +1 more source

Synthesis of substituted triazole-pyrazole hybrids using triazenylpyrazole precursors. [PDF]

open access: yesBeilstein J Org Chem
Gräßle S   +6 more
europepmc   +1 more source

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