Results 31 to 40 of about 25,600 (309)

Strategies to Design and Optimize Artificial Antigen‐Presenting Cells for T Cell Expansion in Cancer Immunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
This review highlights recent advances in engineering artificial antigen‐presenting cells (aAPCs) as alternatives to dendritic cells for T cell expansion. Key design principles inspired by the immunological synapse are discussed, with emphasis on strategies for polyclonal and antigen‐specific T cell expansion.
Nguyen Thi Nguyen, Yu Seok Youn
wiley   +1 more source

A construction of 4,4-spirocyclic γ-lactams by tandem radical cyclization with carbon monoxide

open access: yesBeilstein Journal of Organic Chemistry, 2013
A straightforward synthesis of 4,4-spirocyclic indol γ-lactams by tandem radical cyclization of iodoaryl allyl azides with CO was achieved. The reaction of iodoaryl allyl azides, TTMSS and AIBN under CO pressure (80 atm) in THF at 80 °C gave the desired ...
Mitsuhiro Ueda   +6 more
doaj   +1 more source

Functionalization of Phenyl Rings by Imidoylnitrenes. 3 The Effects of Resonance, Steric, and Inductive Properties on the Reactivity or Selectivity of Nitrenes and the Stability of their Precursors

open access: yesMolecules, 2002
The thermal decomposition of imidoyl azides (ArO-C=N-Z)-N3, (Ar = p-NO2-C6H4-, p-Br-C6H4-, p-Cl-C6H4-, p-C6H5-, p-CH3-C6H4-, 2,4-dimethyl-C6H3-, 2,4,6-trimethyl-C6H2-, p-CH3O-C6H4- and Z = p-CH3-C6H4-SO2-, 2,4,6-trimethyl-C6H2-SO2-,CN) in the solid phase
Reza Karimzadeh, Hossein A. Dabbagh
doaj   +1 more source

Temperature‐Enhanced Supramolecular Polymer Adhesion Provided by Concurrent Utilization of Calix[4]Pyrrole and Crown Ether Molecular Recognition

open access: yesAdvanced Functional Materials, EarlyView.
Simultaneous utilization of calix[4]pyrrole‐ and crown ether‐based molecular recognition allows the construction of a high molecular weight alternating supramolecular polymer. This heat processible polymer can be used as a durable and reusable adhesive on glass and steel with temperature‐enhanced adhesion strength without the need for a solvent ...
Deniz Memis, Abdullah Aydogan
wiley   +1 more source

Reaction of aromatic azides with strong acids: formation of fused nitrogen heterocycles and arylamines

open access: yesJournal of the Brazilian Chemical Society, 1999
We describe in this paper the action of trifluoroacetic acid, trifluoromethanesulfonic acid and aluminum chloride upon ortho-substituted aryl azides to form indoles, azepines and arylamines in good yields.
Carvalho Marcia de   +2 more
doaj  

An Efficient Approach to Phosphorylated Isoindoline Fused with Triazoles via Zn-Catalyzed Cascade Cyclization of 2–Propynol Benzyl Azides and Diarylphosphine Oxides

open access: yesMolecules, 2019
An efficient approach for the synthesis of phosphorylated isoindoline fused with triazoles via Zn(OTf)2-catalyzed cascade cyclization of easily prepared ortho−propynol benzyl azides and diarylphosphine oxides is developed.
Tao Yang   +5 more
doaj   +1 more source

Azides and Porphyrinoids: Synthetic Approaches and Applications. Part 2—Azides, Phthalocyanines, Subphthalocyanines and Porphyrazines

open access: yesMolecules, 2020
The reaction between organic azides and alkyne derivatives via the Cu(I)-catalyzed azide–alkyne cycloaddition (CuAAC) is an efficient strategy to combine phthalocyanines and analogues with different materials.
Ana R. L. Araújo   +8 more
doaj   +1 more source

High‐Throughput Microfluidic‐Mediated Assembly of Layer‐By‐Layer Nanoparticles

open access: yesAdvanced Functional Materials, EarlyView.
The layer‐by‐layer (LbL) assembly of polymer films on nanoparticle (NP) surfaces is a promising technique for targeted drug delivery. Despite its success in preclinical mouse models, a current good manufacturing practices (cGMP) compliant, clinical‐scale production method has been lacking.
Ivan S. Pires   +4 more
wiley   +1 more source

Anionic Citrate‐Based 3D‐Printed Scaffolds for Tunable and Sustained Orthobiologic Delivery to Enhance Tissue Regeneration

open access: yesAdvanced Functional Materials, EarlyView.
A potent anionic citric acid‐based 3D‐printed scaffold is developed for the sustained and controlled release of orthobiologics to enhance orthopedic therapeutic efficacy. Comprehensive in vivo studies demonstrated effective bone fusion and high safety at a low dose of BMP‐2 delivered by the system, establishing it as a promising platform for safe ...
Se‐Hwan Lee   +12 more
wiley   +1 more source

Organic Azides. 3. Ultrasound Synthesis of Propargyl Azide, Azidoacetonitrile and Primary Allylic Azides. [PDF]

open access: yesActa Chemica Scandinavica, 1984
Various applications of ultrasound in heterogeneous reactions have been published.2 This paper describes the direct formation of azides from activated primary organic halides and aqueous sodium azide solution under ultrasonic irradiation D»]. A mixture of the alkyl halide and saturated aqueous sodium azide is irradiated in an Erlenmeyer flask using a ...
Hanno Priebe   +4 more
openaire   +2 more sources

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