Results 21 to 30 of about 683 (135)

Authors’ Reply: Safety of combination therapy of azilsartan medoxomil and amlodipine: a population-based cohort study [PDF]

open access: yesEpidemiology and Health
Hyesung Lee   +9 more
doaj   +2 more sources

Azilsartan medoxomil [PDF]

open access: yes, 2020
Azilsartan is used for treatment of the high blood pressure (hypertension). Reducing high blood pressure enables avoid strokes, heart attacks and problems of kidneys. Azilsartan comes under the name angiotensin receptor blocker (ARBs) as a class of drugs. It acts by relaxing blood vessels to make it easier for blood to flow.
Abdulrahman A, Al-Majed   +4 more
openaire   +3 more sources

The assessment of renal function during the therapy of arterial hypertension with azilsartan medoxomil in patients with obesity or overweight and concomitant metabolic disorders

open access: yesТерапевтический архив, 2021
Aim. To assess the influence of the therapy of arterial hypertension with azilsartan medoxomil on the renal function in overweight or obese patients with concomitant metabolic disorders. Materials and methods.
Vera A. Nevzorova   +3 more
doaj   +1 more source

Efficacy and safety of standard dose triple combination of telmisartan 80 mg/amlodipine 5 mg/chlorthalidone 25 mg in primary hypertension: A randomized, double‐blind, active‐controlled, multicenter phase 3 trial

open access: yesThe Journal of Clinical Hypertension, Volume 25, Issue 9, Page 817-827, September 2023., 2023
Abstract The authors evaluated the efficacy, safety, and characteristics of patients who respond well to standard dose triple combination therapy including chlorthalidone 25 mg with telmisartan 80 mg plus amlodipine 5 mg in hypertensive patients. This is a multicenter, double‐blind, active‐controlled, phase 3, randomized trial.
Eun Joo Cho   +25 more
wiley   +1 more source

Angiotensin II receptor blockers (ARBs) and manufacturing contamination: A retrospective National Register Study into suspected associated adverse drug reactions

open access: yesBritish Journal of Clinical Pharmacology, Volume 88, Issue 11, Page 4812-4827, November 2022., 2022
Aims The aim of this study was to determine if any suspected adverse drug reactions (ADRs) observed with the use of angiotensin II receptor blockers (ARBs) could be linked to either (a) their unique respective physicochemical and pharmacological profiles and (b) the recently disclosed suspected carcinogenic manufacturing contaminants found in certain ...
Hamisha Salim, Alan M. Jones
wiley   +1 more source

CYP2C8*3 and *4 define CYP2C8 phenotype: An approach with the substrate cinitapride

open access: yesClinical and Translational Science, Volume 15, Issue 11, Page 2613-2624, November 2022., 2022
Abstract Cinitapride is a gastrointestinal prokinetic drug, prescribed for the treatment of functional dyspepsia, and as an adjuvant therapy for gastroesophageal reflux disease. In this study, we aimed to explore the impact of relevant variants in CYP3A4 and CYP2C8 and other pharmacogenes, along with demographic characteristics, on cinitapride ...
Diana María Campodónico   +12 more
wiley   +1 more source

Comparative efficacy and safety of fimasartan in patients with hypertension: A network meta‐analysis of randomized controlled trials

open access: yesThe Journal of Clinical Hypertension, Volume 24, Issue 8, Page 971-983, August 2022., 2022
Abstract Hypertension is a prevalent risk factor for cardiovascular disease. Angiotensin II receptor blockers are widely prescribed to patients with hypertension, while new drugs are continuously developed. However, data on comparative efficacy and safety of novel agents, such as fimasartan, are scarce.
Suk Min Seo   +4 more
wiley   +1 more source

Extracellular Vesicle‐Derived circITGB1 Regulates Dendritic Cell Maturation and Cardiac Inflammation via miR‐342‐3p/NFAM1

open access: yesOxidative Medicine and Cellular Longevity, Volume 2022, Issue 1, 2022., 2022
Acute myocardial infarction (AMI) is a complication of atherosclerosis‐related cardiovascular illness that is caused by prolonged ischemia. Circular RNAs (circRNAs) are concentrated in extracellular vesicles (EVs) and have been linked to cardiovascular disease.
Jianbing Zhu   +13 more
wiley   +1 more source

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