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Recent Developments in the Metal-Catalyzed Synthesis of Nitrogenous Heterocyclic Compounds. [PDF]
Zhang X, Bi W, Cao Z, Shen J, Chen B.
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Precise construction of spiro stereocenters <i>via</i> enantioselective radical addition through modulating photocatalysis from redox to energy transfer. [PDF]
Liu F +5 more
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Azirines. V. The Reaction of 2-Phenyl-3, 3-pentamethylene1-azirine with Acid Chlorides
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Carbamoyl Anion Addition to Azirines
Organic Letters, 2021The addition of carbamoyl anions to azirines affords synthetically useful 2-aziridinyl amide building blocks. The reaction scope was explored with respect to both formamide and azirine, and the addition was found to be highly diastereoselective. A one-pot conversion of a ketoxime to an aziridinyl amide was demonstrated.
Michael J. Kerner +9 more
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2H-Azirines in medicinal chemistry
Chemistry of Heterocyclic Compounds, 2021The review presents an analysis of studies published in the period 1971–2020 devoted to examination of the biological activity of natural and synthetic 2H-azirine derivatives, their use for bioconjugation, as well as search for some new synthetic methods of structural modification of azirines with the aim of improving their biological activity.
Pavel А. Sakharov +2 more
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ChemInform Abstract: AZIRINE ALKYLATION
Chemischer Informationsdienst, 1976AbstractDas Azirin (I) wird durch Trifluormethansulfonsäuremethylester zum Salz (III) gespalten, das mit Natriumhydrogencarbonat quantitativ die Base (IV) ergibt und mit verd. Salzsäure in Äthanol zum Pyraziniumsalz (V) cyclisiert.
J. A. DEYRUP, W. A. SZABO
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ChemInform Abstract: AZIRINE PHOTOCHEMISTRY, CYCLIZATION OF 2‐STYRYL‐2H‐AZIRINES TO BENZAZEPINES
Chemischer Informationsdienst, 1974AbstractDie Photolyse der isomeren Phenyl‐styryl‐azirine (I) führt zum Benzazepin (II), dessen Struktur durch Addition von Acetylendicarbonsäureester (III) zum Additionsprodukt (IV) bestätigt wird.
A. PADWA, J. SMOLANOFF
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Organic Letters, 2013
A variety of enaminones and enamine carboxylic esters were converted to trifluoroethoxylated 2H-azirines through reactions with PhIO in trifluoroethanol (TFE). The cascade reaction is postulated to proceed via a PhIO-mediated oxidative trifluoroethoxylation and a subsequent azirination of the α-trifluoroethoxylated enamine intermediates.
Xiaoqian, Sun +4 more
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A variety of enaminones and enamine carboxylic esters were converted to trifluoroethoxylated 2H-azirines through reactions with PhIO in trifluoroethanol (TFE). The cascade reaction is postulated to proceed via a PhIO-mediated oxidative trifluoroethoxylation and a subsequent azirination of the α-trifluoroethoxylated enamine intermediates.
Xiaoqian, Sun +4 more
openaire +2 more sources

