Results 151 to 160 of about 72,034 (334)

Single‐Dose, Intravenous, and Oral Pharmacokinetics of Isavuconazole in Dogs

open access: yesJournal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Isavuconazole, a triazole antifungal used in humans for invasive fungal infections, may be effective for treating canine fungal infections, although data on its use in dogs is limited. This study aimed to determine the pharmacokinetics and safety of a single dose of isavuconazole in dogs, administered both intravenously and orally. Six healthy
Yishan Kuo   +3 more
wiley   +1 more source

Improved Detection and Monitoring of Fungicide Resistance in Blumeria graminis f. sp. hordei With High-Throughput Genotype Quantification by Digital PCR

open access: yesFrontiers in Microbiology, 2018
The increased occurrence of triazole fungicide resistant strains of Blumeria graminis f. sp. hordei (Bgh) is an economic concern for the barley industry in Australia and elsewhere.
Katherine G. Zulak   +4 more
doaj   +1 more source

Fungicide Resistance Genetics of Apple Scab fungus Venturia inaequalis [PDF]

open access: yes, 2015
Apple scab, caused by the ascomycete fungus Venturia inaequalis, is considered the most devastating disease on domestic apple crops. Apples are the most important cultivated crop in temperate regions and the United States produced about 4.6 million tons ...
Reddel, Alexis LT
core   +1 more source

Presumed Trichophyton indotineae Infection in Children: A Call for Heightened Clinical Awareness

open access: yesPediatric Dermatology, EarlyView.
ABSTRACT Trichophyton indotineae is a fungus that is often antifungal‐resistant and presents with exuberant infection. It has been increasingly reported across the world, posing significant diagnostic challenges. We describe a case of a toddler with a history of travel to Bangladesh, presenting with persistent annular scaling plaques of dermatophytosis
Sriram Palepu, James R. Treat
wiley   +1 more source

Sterol C-22 desaturase ERG5 mediates the sensitivity to antifungal azoles in Neurospora crassa and Fusarium verticillioides

open access: yesFrontiers in Microbiology, 2013
Antifungal azoles inhibit ergosterol biosynthesis by interfering with lanosterol 14α-demethylase. In this study, 7 upregulated and 4 downregulated ergosterol biosynthesis genes in response to ketoconazole treatment were identified in Neurospora crassa ...
Xianyun eSun   +7 more
doaj   +1 more source

Overcoming resistance of Candida albicans using photodynamic inactivation

open access: yesPhotochemistry and Photobiology, EarlyView.
The rising resistance of Candida albicans to conventional antifungals, like Amphotericin B (AmB), highlights the need for alternative treatments. This study evaluated the antifungal effectiveness of combining AmB with photodynamic inactivation (PDI) using curcumin as a photosensitizer.
Gabriela Gomes Guimarães   +5 more
wiley   +1 more source

Demethylase Inhibitor Fungicide Resistance in Pyrenophora teres f. sp. teres Associated with Target Site Modification and Inducible Overexpression of Cyp51

open access: yesFrontiers in Microbiology, 2016
Pyrenophora teres f. sp. teres is the cause of net form of net blotch, an economically important foliar disease in barley (Hordeum vulgare). Net and spot forms of net blotch are widely controlled using site-specific systemic fungicides.
Wesley John Mair   +8 more
doaj   +1 more source

Trends in Azole Resistance in Aspergillus fumigatus, the Netherlands, 1994–2016

open access: yesEmerging Infectious Diseases, 2019
We investigated azole resistance in Aspergillus fumigatus in a tertiary reference hospital in the Netherlands during 1994–2016. The 5-year patient-adjusted proportion of resistance increased from 0.79% for 1996–2001 to 4.25% for 2002–2006, 7.17% for 2007–
Jochem B. Buil   +4 more
semanticscholar   +1 more source

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