Results 191 to 200 of about 41,065 (312)

Stereoselective interaction of the azole antifungal agent SCH39304 with the cytochrome P-450 monooxygenase system isolated from Cryptococcus neoformans [PDF]

, 1997
David C. Lamb, Brian C. Baldwin, K. J. Kwon-Chung, Steven L. Kelly   +3 more
openalex   +1 more source

The Structure of Nitro‐ and Polynitropyrazoles: X‐Ray Crystallography Versus Theoretical Calculations

Asian Journal of Organic Chemistry, Volume 14, Issue 10, October 2025.
Abstract This publication presents the geometries of 157 nitro‐ and polynitropyrazoles. Among these, 109 compounds were theoretically studied using mainly the B3LYP/6–311++G(d,p) level of theory. Three‐parameter Lee‐Yang‐Parr (B3LYP) is a density functional theory (DFT) method widely used in computational chemistry and constitutes an acceptable ...
Rosa M. Claramunt, Marta Pérez‐Torralba, José Elguero, Ibon Alkorta   +3 more
wiley   +1 more source

Molecular Rearrangements in Heterocyclic Synthesis. A Generalized Synthesis of 1,2,4-thiadiazoles from 3-Acylamino-1-oxa-2-azoles

, 1994
Nicol� Vivona, Silvestre Buscemi, Nicol� Vivona   +2 more
openalex   +1 more source

Synthesis and Biological Evaluation of Novel 2‐(Piperidin‐4‐yl)‐1,2,3,4‐tetrahydroisoquinoline and 2‐(Piperidin‐4‐yl)decahydroisoquinoline Antimycotics

Archiv der Pharmazie, Volume 358, Issue 10, October 2025.
A series of 13 hybrid molecules of both lead structures were prepared using reductive amination as key reaction step. The antimycotic potency of the resulting compounds was evaluated against yeast and mold species. Two compounds showed remarkable potency against several yeasts, and even against Candida krusei.
Marie‐Christin Hain, Monika Klimt, Franz Bracher, Ulrike Binder, Jürgen Krauß   +4 more
wiley   +1 more source

Azole Resistance of Aspergillus fumigatus in Immunocompromised Patients with Invasive Aspergillosis

Emerging Infectious Diseases, 2016
Alexandre Alanio, Blandine Denis, Samia Hamane, Emmanuel Raffoux, Régis Peffault de Latour, Jean Menotti, Sandy Amorim, Sophie Touratier, Anne Bergeron, Stéphane Bretagne   +9 more
doaj   +1 more source

Real‐world population pharmacokinetics of tezacaftor‐ivacaftor in children with cystic fibrosis: The SYM‐CF study

British Journal of Clinical Pharmacology, Volume 91, Issue 10, Page 2969-2978, October 2025.
Aims The clinical effectiveness of tezacaftor‐ivacaftor in children with cystic fibrosis (cwCF) varies; some patients respond while others do not or have adverse effects. The pharmacokinetics (PK) of tezacaftor‐ivacaftor are inadequately published, especially in children.
Steffie E. M. Vonk, Suzanne W. J. Terheggen‐Lagro, Eric G. Haarman, Hettie M. Janssens, Anke‐Hilse Maitland–van der Zee, E. Marleen Kemper, Ron A. A. Mathôt, on behalf of the Amsterdam Mucociliary Clearance Disease (AMCD) research group   +7 more
wiley   +1 more source

A yeast sterol auxotroph ( erg 25) is rescued by addition of azole antifungals and reduced levels of heme [PDF]

, 1997
Daniel Gachotte, C. A. Pierson, N. Douglas Lees, Robert J. Barbuch, C. Koegel, Martin Bard   +5 more
openalex   +1 more source

Synthesis of 1-(pyrrolidin-2-ylmethyl)-1H-azoles and their piperidine-derived homologues

Open Chemistry, 2014
Zhersh Sergey, Karpenko Oleksandr, Ripenko Vasyl, Tolmachev Andrey, Grygorenko Oleksandr   +4 more
doaj   +1 more source

A Comprehensive Overview of <i>Candida albicans</i> as the Leading Pathogen in Vulvovaginal Candidiasis. [PDF]

J Fungi (Basel)
Srb N, Talapko J, Meštrović T, Fureš R, Stupnišek M, Srb AM, Škrlec I.   +6 more
europepmc   +1 more source

Accumulation of 3-Ketosteroids Induced by Itraconazole in Azole-Resistant ClinicalCandida albicansIsolates

, 1999
Patrick Marichal, J. Gorrens, Leen Laurijssens, Karen Vermuyten, Carl Van Hove, Ludo Le Jeune, Peter Verhasselt, Dominique Sanglard, Μ. Borgers, Frans C.�S. Ramaekers, Frank C. Odds, H. Vanden Bossche   +11 more
openalex   +1 more source