Results 101 to 110 of about 18,004 (163)

Synthesis of Small 3‑Fluoro- and 3,3-Difluoropyrrolidines Using Azomethine Ylide Chemistry

, 2015
Here, we report accessing small 3-fluoropyrrolidines and 3,3-difluoropyrrolidines through a 1,3-dipolar cycloaddition with a simple azomethine ylide and a variety of vinyl fluorides and vinyl difluorides.
Brian T. O’Neill (1566040), Stephanie Scales (1566022), Luis Martinez Alsina (1566028), Fen Wang (285388), Michelle Tran-Dubé (1566034), Indrawan McAlpine (1566031), Mary Nguyen (292236), Michael R. Collins (1309413), Jianmin Sun (345549), Jiaying Zhong (1274637), Sajiv K. Nair (1566019), Joseph S. Warmus (1566037), Jean Matthews (1566025), Jianwei Bian (1523959)   +13 more
core   +1 more source

2,5-Di-tert-butyl-2,5-diethylpyrrolidine-1-oxyls: Where Is a Reasonable Limit of Sterical Loading for Higher Resistance to Reduction?

Molecules
The pyrrolidine nitroxides with four bulky alkyl substituents adjacent to the N–O∙ group demonstrate very high resistance to reduction with biogenic antioxidants and enzymatic systems.
Irina F. Zhurko, Sergey A. Dobrynin, Yurii I. Glazachev, Yuri V. Gatilov, Igor A. Kirilyuk   +4 more
doaj   +1 more source

Azomethine Ylide Cycloaddition/Reductive Heterocyclization Approach to Oxindole Alkaloids:  Asymmetric Synthesis of (−)-Horsfiline

, 2016
The intermolecular [3 + 2] annulation of azomethine ylides with 2(2-nitrophenyl)acrylate dienophiles followed by reductive heterocyclization affords the spiro(indole-pyrrolidine) ring system.
Tullio Pilati (1460311), Giancarlo Cravotto (683692), Giovanni Battista Giovenzana (2416498), Giovanni Palmisano (1617481), Massimo Sisti (2701183)   +4 more
core   +1 more source

Mechanistic insights into the (3 + 2) cycloaddition of azomethine ylide with dimethyl acetylenedicarboxylate <i>via</i> bond evolution theory. [PDF]

RSC Adv
Chellegui M, Al-Mokhtar RM, Salih RN, Benhamed L, Benmetir S, Vicente de Julián-Ortiz J, Mohammad-Salim HA, Ben Ahmed A.   +7 more
europepmc   +1 more source

<i>N</i>-Oxide Insertion into LDA Dimeric Aggregates for Azomethine Ylide Formation: Explicit Solvation in Quantum Mechanical Treatment of Polarized Intermediates. [PDF]

J Org Chem
Neal MJ, Chartier EJ, Lane AM, Hejnosz SL, Jesikiewicz LT, Liu P, Rohde JJ, Lummis P, Fox DJ, Evanseck JD, Montgomery TD.   +10 more
europepmc   +1 more source

Synthesis of Novel Benzofuran Spiro-2-Pyrrolidine Derivatives via [3+2] Azomethine Ylide Cycloadditions and Their Antitumor Activity. [PDF]

Int J Mol Sci
Pan B, Wang T, Zheng L, Dong Z, Liu L, Liu X, Feng T, Zhou Y, Shi Y.   +8 more
europepmc   +1 more source

Heterogeneous graphene oxide as recyclable catalyst for azomethine ylide mediated 1,3 dipolar cycloaddition reaction in aqueous medium. [PDF]

RSC Adv, 2018
Reddy MS, Kumar NS, Chowhan LR.
europepmc   +1 more source

Theoretical Study of the Mechanism of the Formation of Azomethine Ylide from Isatine and Sarcosine and Its Reactivity in 1,3-Dipolar Cycloaddition Reaction with 7-Oxabenzonorbornadiene. [PDF]

Int J Mol Sci
Antol I, Štrbac P, Murata Y, Margetić D.   +3 more
europepmc   +1 more source

New Regio- and Stereoselective Cascades via Unstabilized Azomethine Ylide Cycloadditions for the Synthesis of Highly Substituted Tropane and Indolizidine Frameworks. [PDF]

J Am Chem Soc, 2016
Chen S, Bacauanu V, Knecht T, Mercado BQ, Bergman RG, Ellman JA.   +5 more
europepmc   +1 more source

The Chemistry of Azomethine Ylides Developed in the Institute

, 1988
The research on azomethine ylide 1,3-dipoles, developed in the last five years in the Institute of Advanced Material Study, Kyushu University, is briefly reviewed.
Kanemasa, Shuji, 金政, 修司
core