Results 81 to 90 of about 18,004 (163)

Synthesis of Dihydrouracils Spiro-Fused to Pyrrolidines: Druglike Molecules Based on the 2-Arylethyl Amine Scaffold

Molecules, 2010
The synthesis of a small library of dihydrouracils spiro-fused to pyrrolidines is described. These compounds are synthesized from b-aryl pyrrolidines, providing products with the 2-arylethyl amine moiety, a structural feature often encountered in ...
Daniel Blanco-Ania, Carolina Valderas-Cortina, Pedro H.H. Hermkens, Leo A.J.M. Sliedregt, Hans W. Scheeren, Floris P.J.T. Rutjes   +5 more
doaj   +1 more source

Bis‐Furans: A Sustainable Source of Diverse Molecular Architectures

European Journal of Organic Chemistry, Volume 29, Issue 10, 9 March 2026.
A concise synthetic route to diverse acyclic and heterocyclic compounds has been developed by combining hetero‐Diels–Alder reactions, DBU‐promoted ring openings, and Lewis base‐catalyzed annulations. Nitrosoalkenes reacted with furan derivatives to form 4a,7a‐dihydro‐4H‐furo[2,3‐e][1,2]oxazines, which underwent DBU‐promoted rearrangements to 6H‐1,2 ...
Ana L. Cardoso, José A. Paixão, Teresa M. V. D. Pinho e Melo   +2 more
wiley   +1 more source

Dipolar cycloaddition reactions of isatin derived azomethine ylide with 3,4-diphenylcyclobutene-1,2-dione: synthesis of novel spiro[oxindole-3,2'-pyrrolidine] derivatives

, 2000
Azomethine ylide, generated by the decarboxylative condensation of sarcosine with isatins has been trapped by 3,4-diphenylcyclobutene-1,2-dione to afford novel spiro[oxindole-3,2'-pyrrolidine ...
Sheela, K. C., Rath, Nigam P., Nair, Vijay   +2 more
core   +1 more source

Synthesis of N-Unsubstituted 1,3-Thiazolidines by [2+3]-Cycloaddition of an Azomethine Ylide with Thiocarbonyl Compounds

, 2003
1,3-Dipolar cycloadditions of azomethine ylides with thiocarbonyl compounds have been used for the preparation of N-unsubstituted 1,3-thiazolidines. The reactive 1-phenyl-N-(trimethylsilyl)azomethine ylide (1c) was generated in situ by treatment of N ...
Gebert, Andreas, Heimgartner, Heinz, Linden, Anthony; https://orcid.org/, Mlostoń, Grzegorz; https://orcid.org/   +3 more
core   +1 more source

Synthesis of Heterocyclic Compounds Through Oxazolium Salt and Azomethine Ylide Cycloaddition

, 2016
Heterocyclic compounds such as pyrroles and pyridines are notably useful for medicinal purposes. Heterocyclic pyrrole rings are present in naturally-occurring cofactors, such as in hemoglobin and chlorophyll, and are present in drugs used today to treat ...
Rourk, Seth
core  

Photochemical synthesis of 1,2,4-triazoles via addition reaction of triplet intermediates to diazoalkanes and azomethine ylide intermediates. [PDF]

Chem Sci, 2022
Cai BG, Bao YP, Pei C, Li Q, Li L, Koenigs RM, Xuan J.   +6 more
europepmc   +1 more source

General Pyrrolidine Synthesis via Iridium-Catalyzed Reductive Azomethine Ylide Generation from Tertiary Amides and Lactams. [PDF]

ACS Catal, 2021
Yamazaki K, Gabriel P, Di Carmine G, Pedroni J, Farizyan M, Hamlin TA, Dixon DJ.   +6 more
europepmc   +1 more source

New Zinc(II)-Based Catalyst for Asymmetric Azomethine Ylide Cycloaddition Reactions

, 2016
A new chiral aziridino alcohol ligand for zinc(II)-catalyzed azomethine ylide cycloadditions is described. In the presence of this catalyst, N-arylidene glycine methyl esters react with a variety of dipolarophiles to give substituted pyrrolidines in very
Hasan Koyuncu (2400475), Özdemir Dogan (2480350), Matthew Panzner (2524462), Philip Garner (1831117), Wiley J. Youngs (1651099), Adnan Bulut (2418232)   +5 more
core   +1 more source

Covalent organic functionalization of graphene nanosheets and reduced graphene oxide via 1,3-dipolar cycloaddition of azomethine ylide. [PDF]

Nanoscale Adv, 2021
Basta L, Moscardini A, Fabbri F, Bellucci L, Tozzini V, Rubini S, Griesi A, Gemmi M, Heun S, Veronesi S.   +9 more
europepmc   +1 more source

Stereospecific route to 5,11-methanomorphanthridine alkaloids via intramolecular 1,3-dipolar cycloaddition of nonstabilized azomethine ylide: formal total synthesis of (±)-pancracine

, 2005
The core structure of the complex pentacyclic 5,11-methanomorphanthridine alkaloids is constructed stereospecifically in one step employing an intramolecular [3 + 2]-cycloaddition of nonstabilized azomethine ylide as the key step.
Banerjee, Prabal, Kumar, Ravindra, Pandey, Ganesh, Puranik, Vedavati G.   +3 more
core   +1 more source