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Spirooxindoles: Promising scaffolds for anticancer agents
European Journal of Medicinal Chemistry, 2015The search for novel anticancer agents with more selectivity and lower toxicity continues to be an area of intensive investigation. The unique structural features of spirooxindoles together with diverse biological activities have made them privileged structures in new drug discovery.
Bin Yu, Hong-Min Liu
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Therapeutic Potential of Spirooxindoles as Antiviral Agents [PDF]
ACS Infectious Diseases, 2016 Antiviral therapeutics with profiles of high potency, low resistance, panserotype, and low toxicity remain challenging, and obtaining such agents continues to be an active area of therapeutic development. Due to their unique three-dimensional structural features, spirooxindoles have been identified as privileged chemotypes for antiviral drug ...
Na Ye, Haiying Chen, Eric A Wold
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Recent advances in the synthesis of biologically active spirooxindoles
Tetrahedron, 2014Maria M M Santos
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N‐Heterocyclic Carbene/Copper Cooperative Catalysis for the Asymmetric Synthesis of Spirooxindoles
Angewandte Chemie - International Edition, 2019Jin Song, Xiao-Hua Chen, Liu-Zhu Gong
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Catalytic Stereoselective Synthesis of Diverse Oxindoles and Spirooxindoles from Isatins
ACS Combinatorial Science, 2012Annaliese K Franz
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