Results 41 to 50 of about 1,887 (208)

Recent Advances in Green Approaches for Synthesis of Oxindole Derivatives [PDF]

, 2023
Oxindole derivatives are nitrogen-containing, five-membered heterocyclic molecules found in both natural and synthetic substances with diverse biological functions.
D.M.T.A.Samaradiwakara, H.H.Kandambi, K.G.U.R. Kumarasinghe   +2 more
core   +2 more sources

3′-Methyl-2-oxo-1′,5′-diphenyl-1′,7′-dihydrospiro[indoline-3,4′-pyrazolo[3,4-b]pyridine]-6′-carboxylic Acid

Molbank, 2021
3′-methyl-2-oxo-1′,5′-diphenyl-1′,7′-dihydrospiro[indoline-3,4′-pyrazolo[3,4-b]pyridine]-6′-carboxylic acid was synthesized using diverse conditions. The best reaction condition consisted of using water as solvent under microwave irradiation, affording ...
Pablo E. Romo, Braulio Insuasty, Jairo Quiroga, Rodrigo Abonia   +3 more
doaj   +1 more source

Synthesis and Characterization of New Spirooxindoles Including Triazole and Benzimidazole Pharmacophores via [3+2] Cycloaddition Reaction: An MEDT Study of the Mechanism and Selectivity

Molecules, 2023
A new series of spirooxindoles based on benzimidazole, triazole, and isatin moieties were synthesized via a [3+2] cycloaddition reaction protocol in one step. The single X-ray crystal structure of the intermediate triazole-benzimidazole 4 was solved. The
Saeed Alshahrani, Abdullah Mohammed Al-Majid, Abdullah Saleh Alamary, M. Ali, Mezna Saleh Altowyan, Mar Ríos-Gutiérrez, Sammer Yousuf, Assem Barakat   +7 more
doaj   +1 more source

Deep Eutectic Solvents: The Organic Reaction Medium of the Century [PDF]

, 2016
This microreview summarizes the use of deep eutectic solvents (DESs) and related melts in organic synthesis. Solvents of this type combine the great advantages of other proposed environmentally benign alternative solvents, such as low toxicity, high ...
Abbott, Abbott, Abbott, Abbott, Abbott, Abbott, Abbott, Abo-Hamad, Amelio, Aparicio, Assanosi, Azizi, Azizi, Azizi, Azizi, Azizi, Azizi, Azizi, Azizi, Azizi, Azizi, Azizi, Azizi, Azizi, Azizi, Azizi, Azizi, Azizi, Bafti, Bakavoli, Beckman, Bednarz, Borse, Cao, Cardellini, Carriazo, Chahdoura, Chai, Chaskar, Chen, Chen, Constable, Cragg, Dai, Dai, Dai, Dai, Davey, De Oliveira Vigier, De Oliveira Vigier, De Santi, del Monte, Disale, Domínguez de María, Domínguez de María, Duan, Dupont, Durand, Díaz-Álvarez, Earle, Ferreira, Fischer, Francisco, Gambino, García, García-Verdugo, García-Álvarez, García-Álvarez, Gill, Gore, Gorke, Gu, Guajardo, Gupta, Hallet, Handy, Handy, Handy, Hari, Hawkins, Hayyan, Henderson, Hu, Hu, Ilgen, Ilgen, Imperato, Imperato, Imperato, Itoh, Jella, Jérôme, Karmakar, Kemeling, Keshavarzipour, Khandelwal, Krishnakumar, Kumar, Kus, Laird, Lavilla, Li, Li, Li, Li, Lindström, Liu, Liu, Liu, Lobo, Lobo, Lu, Macaev, Machida, Mahboub, Mallardo, Martins, Matsuda, Maugeri, Maugeri, Maugeri, Mobinikhaledi, Morales, More, Müller, Müller, Pace, Pal, Pandey, Patil, Pavia, Pawar, Pednekar, Pena-Pereira, Pena-Pereira, Peters, Phadtare, Phadtare, Pincock, Pérez, Pérez-Sánchez, Radošević, Rastogi, Reddy, Rodríguez-Álvarez, Ruß, Saberi, Sanap, Sanap, Santos, Sassone, Scholten, Serrano, Sheldon, Shuklov, Singh, Singh, Singh, Singh, Singh, Smith, Sonawane, Steinrück, Stepankova, Sunitha, Tanaka, Tang, Tang, Vidal, Vidal, Vidal, Wagle, Wang, Wang, Wang, Wang, Wang, Wang, Wasserscheid, Welton, Xia, Yadav, Yadav, Yadav, Yu, Zhang, Zhang, Zhang, Zhang, Zhang, Zhang, Zhao, Zhao   +192 more
core   +2 more sources

1,3-Dipolar cycloadditions of azomethine imines [PDF]

, 2015
Azomethine imines are considered 1,3-dipoles of the aza-allyl type which are transient intermediates and should be generated in situ but can also be stable and isolable compounds.
Nájera, Carmen, Sansano, Jose M., Yus, Miguel   +2 more
core   +3 more sources

Design, synthesis, and antitumor activity of novel dispiro[oxindole-cyclohexanone]-pyrrolidines [PDF]

, 2022
Background: Spirooxindoles are privileged scaffolds in medicinal chemistry, which were identified through Wang’s pioneering work as inhibitors of MDM2-p53 interactions.
Azab, Mohamed, Bawzeer, Majed, Elagawany, Mohamed, Elgendy, Bahaa, Gouda, Magy, Hegazy, Lamees, Rateb, Mostafa, Yaseen, Mohammed   +7 more
core   +2 more sources

Photochemical aryl radical cyclizations to give (E)-3-Ylideneoxindoles [PDF]

, 2014
(E)-3-Ylideneoxindoles are prepared in methanol in reasonable to good yields, as adducts of photochemical 5-exo-trig of aryl radicals, in contrast to previously reported analogous radical cyclizations initiated by tris(trimethylsilyl)silane and azo ...
Aldabbagh, Fawaz, Allart-Simon, Ingrid, Gerard, Stephane, Gurry, Michael, McArdle, Patrick, Sapi, Janos   +5 more
core   +2 more sources

Recent Advances in Biocatalytic Promiscuity: Hydrolase-Catalyzed Reactions for Nonconventional Transformations [PDF]

, 2015
Financial support from the Spanish Ministerio de Economía y Competitividad (CTQ2013-44153-P) is grateful acknowledged. M.L.-I.
Gotor Fernández, Vicente, López Iglesias, María   +1 more
core   +2 more sources

Enantioselective Synthesis of Spiro[indolizidine-1,3 '-oxindoles] [PDF]

, 2020
A three-step procedure for the enantioselective synthesis of spiro[indolizidine-1,3'-oxindoles], consisting of a stereoselective cyclocondensation reaction between (S)-tryptophanol and a prochiral or racemic 5-oxoester, bromination of the resulting ...
Amat Tusón, Mercedes, Bosch Cartes, Joan, Gazzola, Silvia, Luque Garriga, F. Xavier, Massi, Lucia, Molins i Grau, Elies, Pérez Bosch, Maria, Ramos, Carlos, Taglienti, Chiara, Viayna Gaza, Antonio, Yayik, Nihan   +10 more
core   +1 more source

Iodide/H2O2 Catalyzed Intramolecular Oxidative Amination for the Synthesis of 3,2′-Pyrrolidinyl Spirooxindoles

Molecules, 2018
An ammonium iodide/hydrogen peroxide-mediated intramolecular oxidative amination of 3-aminoalkyl-2-oxindoles was achieved, affording the corresponding 3,2′-pyrrolidinyl spirooxindoles and their 6- or 7-membered analogous in moderate to high yields.
Yu-Ting Gao, Xiao-Yang Jin, Qi Liu, An-Di Liu, Liang Cheng, Dong Wang, Li Liu   +6 more
doaj   +1 more source