Results 51 to 60 of about 1,205 (207)

Innovating Electrosynthesis From Metal Electrodeposition to Organic Chemistry: Deep Eutectic Solvents as Efficient and Sustainable Media

ChemSusChem, Volume 19, Issue 11, 15 June 2026.
This review analyzes deep eutectic solvents (DESs) as efficient media for both organic and inorganic electrosynthesis. The improvements in terms of synthetic opportunities and sustainability are discussed, by exploring the multiple roles of DESs as solvents, electrolytes, and promoters, enabling effective and selective electrosynthesis under mild and ...
Cristiana Margarita, Stefano Nejrotti, Alejandro Leal‐Duaso, Marta Feroci, Alessandra Sanson, Claudia Barolo, Matteo Bonomo   +6 more
wiley   +1 more source

Organoiodine reagent-promoted intermolecular oxidative amination: synthesis of cyclopropyl spirooxindoles

, 2017
An organoiodine-promoted intramolecular direct oxidative C(sp2)–N cross-coupling reaction was developed for the preparation of cyclopropyl spirooxindoles from readily available secondary cyclopropyl carboxamides.
Zhiguo Zhang, Yongchao Zhang, Guoqing Huang, Guisheng Zhang   +3 more
core   +1 more source

Efficient and green pathway for one-pot synthesis of spirooxindoles in the presence of CuO nanoparticles

Green Chemistry Letters and Reviews, 2017
In this research, a new, green and eco-friendly method for the synthesis of spirooxindole derivatives was presented. The reaction was performed at room temperature in the presence of catalytic amounts (4 mol.%) of CuO nanoparticles and products were ...
Leila Moradi, Zeynab Ataei
doaj   +1 more source

A novel one-pot synthesis of spirooxindole derivatives catalyzed by nano ZnO

Bulletin of the Chemical Society of Ethiopia, 2013
Nano zinc oxide was explored as a heterogeneous and reusable catalyst for the one-pot synthesis of spirooxindoles via three-component reaction between urea, isatin, and 1,3-dicarbonyl compounds.
B. Baghernejad, M. Khorshidi
doaj   +1 more source

Biosynthetically‐Inspired Oxidative Cleavage Platform Enables Rapid Access to Diverse and Architecturally Complex Chemotypes From Indole Alkaloids

ChemistryEurope, Volume 4, Issue 4, April 2026.
We report a biosynthesis‐inspired ring distortion approach that involves oxidative ring cleavage, ring rearrangement, and ring expansion reactions from a diverse collection of indole alkaloids and derivatives. This chemical synthesis approach led to the synthesis of >25 distinct chemotypes from 14 indole alkaloids.
Derek A. Leas, Eli S. Levit, Alexis A. Bragg, Taylor A. Gerrein, Khalil A. Abboud, Pingrong Wei, Lukasz M. Dobrzycki, Robert W. Huigens III   +7 more
wiley   +1 more source

Photoinduced Synthesis of Functionalized Oxacyclic Spirooxindoles Via Ring Expansion

, 2023
A versatile photochemical ring-expansion protocol for the synthesis of oxacyclic spirooxindoles under catalyst-free conditions is described. The reaction is enabled by the use of unstrained O-containing heterocycles with 3-diazoindolin-2-ones under ...
Zhuoheng Song, Bin Li (39349), Lin Guo (113004), Wujiong Xia, Jinrui Bai (14424166), Bin Li, Jinrui Bai, Wujiong Xia (1393906), Chao Yang (174810), Dan Qi, Lin Guo, Zhuoheng Song (12977513), Chao Yang, Dan Qi (33361)   +13 more
core   +1 more source

Stereoselective Synthesis of Five-Membered Spirooxindoles through Tomita Zipper Cyclization

, 2013
Functionalized five-membered spirooxindoles were furnished in good yields and excellent stereoselectivities by using an effective Tomita zipper cyclization (TZC) reaction through organophosphine ...
D. B. Ramachary, Ramachary, D. B., Krishna, Patoju M., Chintalapudi Venkaiah, Patoju M. Krishna, Venkaiah, Chintalapudi   +5 more
core   +1 more source

Selective construction of dispiro[indoline-3,2'-quinoline-3',3''-indoline] and dispiro[indoline-3,2'-pyrrole-3',3''-indoline] via three-component reaction

Beilstein Journal of Organic Chemistry, 2023
A convenient synthetic procedure for the construction of novel dispirooxindole motifs was successfully developed by base-promoted three-component reaction of ammonium acetate, isatins and in situ-generated 3-isatyl-1,4-dicarbonyl compounds.
Ziying Xiao, Fengshun Xu, Jing Sun, Chao-Guo Yan   +3 more
doaj   +1 more source

Chemo-/Regio-Selective Synthesis of Novel Functionalized Spiro[pyrrolidine-2,3′-oxindoles] under Microwave Irradiation and Their Anticancer Activity

Molecules, 2023
A novel series of nitrostyrene-based spirooxindoles were synthesized via the reaction of substituted isatins 1a–b, a number of α-amino acids 2a–e and (E)-2-aryl-1-nitroethenes 3a–e in a chemo/regio-selective manner using [3+2] cycloaddition (Huisgen ...
Richa Sharma, Lalit Yadav, Ali Adnan Nasim, Ravi Kant Yadav, Rui Hong Chen, Neha Kumari, Fan Ruiqi, Ashoke Sharon, Nawal Kishore Sahu, Sirish Kumar Ippagunta, Paolo Coghi, Vincent Kam Wai Wong, Sandeep Chaudhary   +12 more
doaj   +1 more source

Molecular Iodine Catalysed One Pot Synthesis of Spirooxindoles by Tandem Knoevenagel Cyclisation

, 2017
Spirooxindoles are heterocycles found in various natural and synthetic products with potent bio-, physio-, and pharmaceutical activities. Heterocyclic fused phthalazines possess   antimicrobial, antifungal, anticancer, anti- inflammatory, and cardiotonic
Aatika Nizam Anitha Varghese
core   +2 more sources