Expanding the chemical diversity of spirooxindoles via alkylative pyridine dearomatization
A mild and practical synthesis of spirooxindole [1,3]oxazino derivatives from N-substituted isatins and 1,3-dicarbonyl compounds with pyridine derivatives is reported. The reactions provided good to excellent yields.
Chunhui Dai +2 more
doaj +1 more source
The synthesis of Octakis [3- (3-amino propyl triethoxysilane) propyl] octa-silsesquioxane (APTPOSS), a derivative of polyhedral oligomeric silsesquioxane, was utilized to produce an efficient nanocomposite.
Samira Moein-Najafabadi +1 more
doaj +1 more source
Nanoformulation of Spirooxindole and Methods for Treating Hepatocellular Carcinoma
Objectives: This in vivo study introduces a newly developed spirooxindole derivative that is deemed safe and effective as a potential targeted therapy for various cancers. Methods: Extensive in vivo investigations, including histopathology, immunohistochemistry, and molecular biology, validated its potential for further preclinical and clinical ...
Assem Barakat +6 more
openaire +3 more sources
Enantioselective cyclization reactions involving 3-isothiocyanato oxindoles: synthesis of spirocycles. [PDF]
Edareh MH +4 more
europepmc +1 more source
Recent advances of azomethine ylides for the synthesis of natural and synthetic bioactive pyrrolidines and spiropyrrolidines. [PDF]
Paira P +4 more
europepmc +1 more source
Base-Mediated Tandem Michael Addition and SuFEx Cyclization for the Synthesis of Sultone-Containing Spirooxindoles. [PDF]
Govender KB +6 more
europepmc +1 more source
Biochar: a robust and renewable basic carbocatalyst for sustainable synthesis of diversified spirooxindoles. [PDF]
Khoy A, Khalili D, Boostani HR.
europepmc +1 more source
Synthesis and structural elucidation of a novel bis-spirooxindole from isatin and ethylenediamine. [PDF]
Moreno-Gutiérrez I +7 more
europepmc +1 more source
Synthesis of COF-SO<sub>3</sub>H immobilized on manganese ferrite nanoparticles as an efficient nanocomposite in the preparation of spirooxindoles. [PDF]
Moein Najafabadi S, Safaei Ghomi J.
europepmc +1 more source
Oxidative Rearrangement of Indoles Enabled by Promiscuous Cryptic Halogenation with Vanadium-Dependent Haloperoxidases. [PDF]
Lee HJ +7 more
europepmc +1 more source

