Results 71 to 80 of about 1,205 (207)

PyBidine–Ni(OAc)₂‑Catalyzed Michael/Aldol Reaction of Methyleneindolinones and Thiosalicylaldehydes for Stereochemically Divergent Thiochromanyl-spirooxindoles

, 2016
(S,S)-Diphenylethylenediamine-derived bis­(imidazolidine)­pyridine (PyBidine)–Ni­(OAc)2 complex catalyzed the asymmetric Michael/aldol reaction of methyleneindolinone and thiosalicylaldehyde to produce (2′R,3S,4′R)-thiochromanyl-spirooxindole having ...
Takayoshi Arai (1507834), Hyuma Masu (1591576), Hiroki Ogawa (1498804), Tomoya Miyazaki (1507837)   +3 more
core   +1 more source

Complete transfer of chirality in an intramolecular, thermal [2 + 2] cycloaddition of allene-ynes to form non-racemic spirooxindoles

Beilstein Journal of Organic Chemistry, 2011
A thermal [2 + 2] cycloaddition reaction of allene-ynes has been used to transform chiral non-racemic allenyl oxindoles into chiral non-racemic spirooxindoles containing an alkylidene cyclobutene moiety.
Kay M. Brummond, Joshua M. Osbourn
doaj   +1 more source

Electrochemical Enantioselective Oxidation of Indoles via Chiral Phosphoric Acid Catalysis in Cooperation with H3PO4 in Aqueous Media

Angewandte Chemie, Volume 137, Issue 33, August 11, 2025.
A binary organic–inorganic acid cooperative catalytic system has been developed to achieve highly enantioselective electrochemical oxidative rearrangement of indoles. The use of electricity as an oxidant in this case showed several advantages including environmental benignity and improved enantiocontrol.
Xuefeng Tan, Zhijie Zhou, Minhua Shao, Jianwei Sun   +3 more
wiley   +1 more source

Asymmetric Michael/Cyclization Cascade Reaction of 3-Isothiocyanato Oxindoles and 3-Nitroindoles with Amino-Thiocarbamate Catalysts: Enantioselective Synthesis of Polycyclic Spirooxindoles

, 2015
An unprecedented organocatalytic asymmetric Michael/cyclization cascade reaction of 3-isothiocyanato oxindoles and. 3-nitroindoles has-been disclosed. A wide range of enantioenriched polycyclic, spirooxindoles, containing three contiguous chiral centers ...
Zhou, Ming-Qiang, Yuan, Wei-Cheng, Xu, Xiao-Ying, Zhang, Xiao-Mei, Yuan, WC (reprint author), Chinese Acad Sci, Chengdu Inst Organ Chem, Natl Engn Res Ctr Chiral Drugs, Chengdu 610041, Peoples R China., Wu, Zhi-Jun, Zhao, Jian-Qiang, Yue, Deng-Feng, Wang, Zhen-Hua   +8 more
core   +1 more source

Mechanochemical Activation of NaHCO3: A Solid CO2 Surrogate in Carboxylation Reactions

ChemSusChem, Volume 18, Issue 14, July 17, 2025.
This study presents sodium bicarbonate (NaHCO3) as a safe, solid source of CO2 for mechanochemical carboxylation reactions. Mechanochemical methods for synthesizing cyclic carbamates and organic carbonates from NaHCO3 are developed. This approach holds significant potential for pharmaceutical applications, highlighting solvent‐minimized synthesis and ...
Francesco Mele, Andrea Aquilini, Ana Maria Constantin, Francesco Pancrazzi, Lara Righi, Andrea Porcheddu, Raimondo Maggi, Daniele Alessandro Cauzzi, Giovanni Maestri, Elena Motti, Luca Capaldo, Nicola Della Ca'   +11 more
wiley   +1 more source

Electronic_supplementary___information – Supplemental material for Preparation of spirooxindoles catalyzed by nano-Co3S4 under microwave irradiations

, 2019
Supplemental material, Electronic_supplementary___information for Preparation of spirooxindoles catalyzed by nano-Co3S4 under microwave irradiations by Sheida Khojasteh-Khosro and Hossein Shahbazi-Alavi in Journal of Chemical ...
Sheida Khojasteh-Khosro (6643637), Hossein Shahbazi-Alavi (4344214)   +1 more
core   +1 more source

Regioselective pyrrolizidine bis-spirooxindoles as efficient anti-amyloidogenic agents

, 2022
Here, we report a microwave-assisted, one-pot, three-component, 1,3-dipolar cycloaddition reaction to produce highly regioselective and stereoselective bis-spirooxindoles as potential inhibitors against amyloid-? fibrillation.
Anthony Dahdah (20082063), Ewan Blanch (18026569), Nilamuni De Silva (20074632), Helmut Hugel (598849), Subashani Maniam (18032776)   +4 more
core  

Synthesis of Isoxazolopyridines and Spirooxindoles under Ultrasonic Irradiation and Evaluation of Their Antioxidant Activity

Journal of Chemistry, 2017
New polycyclic-fused isoxazolo[4,5-e]pyridines and spirooxindoles were obtained via multicomponent reaction of 5-amino-3-methylisoxazole, indan-1,3-dione, and aromatic aldehydes and reaction of 5-amino-3-methylisoxazole, isatin, and β-diketones in the ...
Emel Pelit
doaj   +1 more source

Catalysis With Deep Eutectic Solvents: Challenges and Opportunities

ChemCatChem, Volume 17, Issue 11, June 6, 2025.
Deep eutectic solvents (DESs) are emerging as sustainable alternatives in catalysis, offering tunable properties for diverse chemical transformations. This review explores the dual role of DESs as solvents and catalysts, highlighting advancements in organic chemistry, materials science, CO2 fixation, biomass valorization, polymer degradation, and ...
Eduardo Guzmán
wiley   +1 more source

TCCA-mediated oxidative rearrangement of tetrahydro-β-carbolines: Facile access to spirooxindoles and the total synthesis of (±)-coerulescine and (±)-horsfiline

, 2021
Multi-reactive centered reagents are beneficial in chemical synthesis due to their advantage of minimal material utilization and formation of less by-products.
Sakla, Akash P., Sathish, Manda, Santos, Leonardo S., Shankaraiah, N., Nachtigall, Fabiane Manke   +4 more
core   +1 more source