Results 91 to 100 of about 1,887 (208)
Mechanochemical Activation of NaHCO3: A Solid CO2 Surrogate in Carboxylation Reactions
ChemSusChem, Volume 18, Issue 14, July 17, 2025.This study presents sodium bicarbonate (NaHCO3) as a safe, solid source of CO2 for mechanochemical carboxylation reactions. Mechanochemical methods for synthesizing cyclic carbamates and organic carbonates from NaHCO3 are developed. This approach holds significant potential for pharmaceutical applications, highlighting solvent‐minimized synthesis and ...
Francesco Mele +11 more
wiley +1 more source
Beilstein Journal of Organic Chemistry, 2011 A thermal [2 + 2] cycloaddition reaction of allene-ynes has been used to transform chiral non-racemic allenyl oxindoles into chiral non-racemic spirooxindoles containing an alkylidene cyclobutene moiety.
Kay M. Brummond, Joshua M. Osbourn
doaj +1 more source
ChemistrySpirooxindoles are a family of heterocyclic compounds which bear the oxindole nucleus in their structures, which have a considerable pharmaceutical potential and which have been linked to various drugs for the treatment of diverse diseases. In this work,
Pablo Romo +6 more
doaj +1 more source
Ionic Liquids Immobilized on Magnetic Nanoparticles [PDF]
, 2017 Ionic liquids (ILs) immobilized on supports are among the most important derivatives of ILs. The immobilization process of ILs can transfer their desired properties to substrates.
Mokhtary, Masoud
core +1 more source
Catalysis With Deep Eutectic Solvents: Challenges and Opportunities
ChemCatChem, Volume 17, Issue 11, June 6, 2025.Deep eutectic solvents (DESs) are emerging as sustainable alternatives in catalysis, offering tunable properties for diverse chemical transformations. This review explores the dual role of DESs as solvents and catalysts, highlighting advancements in organic chemistry, materials science, CO2 fixation, biomass valorization, polymer degradation, and ...
Eduardo Guzmán
wiley +1 more source
From data to discovery: leveraging big data in plant natural products biosynthesis research
The Plant Journal, Volume 122, Issue 6, June 2025.SUMMARY Plant natural products or specialized metabolites play a vital role in drug discovery and development, with many clinically important derivatives such as the anticancer drugs topotecan (derived from the natural alkaloid camptothecin) and etoposide (derived from the natural polyphenol podophyllotoxin).
Matthew McConnachie +4 more
wiley +1 more source
ChemistrySelect, Volume 10, Issue 17, May 5, 2025.A new set of spirooxindole‐ and spiroindenoquinoxaline‐derived pyrrolo[3,4‐c] pyrroles has been synthesized through atom‐economic one‐pot multicomponent reactions. Based on the results, compounds 4b and 5a demonstrated promising Glide scores and exhibited strong binding affinity with decaprenylphosphoryl‐β‐D‐ribofuranose oxidoreductase.
Mathiyazhagan Lavanya +8 more
wiley +1 more source
Journal of Chemistry, 2017 New polycyclic-fused isoxazolo[4,5-e]pyridines and spirooxindoles were obtained via multicomponent reaction of 5-amino-3-methylisoxazole, indan-1,3-dione, and aromatic aldehydes and reaction of 5-amino-3-methylisoxazole, isatin, and β-diketones in the ...
Emel Pelit
doaj +1 more source
Recent Developments in the Synthesis of Chiral Compounds with Quaternary Centers by Organocatalytic Cascade Reactions [PDF]
, 2016 Quaternary carbon stereocenters are present in a wide variety of organic compounds and drug molecules. Highly enantioselective construction of such quaternary carbon stereocenters has received considerable attention owing to the great challenges in their
Ahrendt +98 more
core +1 more source