Results 81 to 90 of about 1,887 (208)
Catalytic asymmetric synthesis of biologically important 3-hydroxyoxindoles: an update
Beilstein Journal of Organic Chemistry, 2016 Oxindole scaffolds are prevalent in natural products and have been recognized as privileged substructures in new drug discovery. Several oxindole-containing compounds have advanced into clinical trials for the treatment of different diseases. Among these
Bin Yu +3 more
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Molecules, 2023 A novel series of nitrostyrene-based spirooxindoles were synthesized via the reaction of substituted isatins 1a–b, a number of α-amino acids 2a–e and (E)-2-aryl-1-nitroethenes 3a–e in a chemo/regio-selective manner using [3+2] cycloaddition (Huisgen ...
Richa Sharma +12 more
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Синтез і хімічні властивості конденсованих та спіросполучених похідних піролу [PDF]
, 2018 У дисертаційній роботі досліджено стереохімію та регіонаправленість фор-мування продуктів у процесах 1,3-диполярного циклоприєднання азометин-ілідів на основі ізатину та циклічних і аліфатичних α-амінокислот до похідних N-заміщених малеїнімідів ...
Павловська, Т.Л.
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Synthesis, characterization and thermal decomposition of 2’-amino-6’-(1H-indol-3-yl)-1-methyl-2-oxospiro-[indoline-3,4’-pyran]-3’,5’-dicarbonitrile under non-isothermal condition in nitrogen atmosphere [PDF]
, 2016 The kinetics and decomposition of a new spirooxindole compound, 2’-amino-6’-(1H-indol-3-yl)-1-methyl-2-oxospiro[indoline-3,4’-pyran]-3’,5’-dicarbonitrile was studied by thermo gravimetric technique under non-isothermal conditions.
Jayachandramani, Natesan +4 more
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Stereoselective Synthesis of Spirooxindole Amides through Nitrile Hydrozirconation [PDF]
Organic Letters, 2010 Spirooxindole amides can be prepared by the intramolecular addition of functionalized indoles into acylimines that are accessed from nitriles by hydrozirconation and acylation. The stereochemical outcome at the quaternary center was controlled by the steric bulk of the substituent at the 2-position of the indole unit.
Chunliang, Lu +2 more
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Construction of Spirooxindole Skeleton Through Intramolecular Dieckmann Cyclization
Natural Products and Bioprospecting, 2017 A highly efficient and direct approach was developed to construct the structurally diverse spirooxindole skeleton, which is an important basic motif in natural products.
Ting Wu, Zhiqiang Pan, Chengfeng Xia
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Molbank, 2021 The multicomponent reactions are environmentally benign synthetic methods of building-up of complex molecules and several levels of structural diversity for diverse applications.
Yuliya E. Ryzhkova +2 more
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Molecular Iodine Catalysed One Pot Synthesis of Spirooxindoles by Tandem Knoevenagel Cyclisation [PDF]
, 2021 Spirooxindoles are heterocycles found in various natural and synthetic products with potent bio-, physio-, and pharmaceutical activities. Heterocyclic fused phthalazines possess antimicrobial, antifungal, anticancer, anti- inflammatory, and ...
Anitha Varghese, Aatika Nizam
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Results in Chemistry, 2020 With their exceptional three-dimensional structural topographies, spirooxindoles are known best for privileged chemotypes for diverse biological applications.
Dhruba Jyoti Boruah +2 more
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Angewandte Chemie, Volume 137, Issue 33, August 11, 2025.A binary organic–inorganic acid cooperative catalytic system has been developed to achieve highly enantioselective electrochemical oxidative rearrangement of indoles. The use of electricity as an oxidant in this case showed several advantages including environmental benignity and improved enantiocontrol.
Xuefeng Tan +3 more
wiley +1 more source