Results 41 to 50 of about 18,004 (163)

Synthesis of the Tricyclic Core of Sarain A. Use of Formaldehyde in an Intramolecular Grigg Azomethine Ylide Cyclization

, 2016
Synthesis of the Tricyclic Core of Sarain A.
Clayton H. Heathcock (2713198), David A. Griffith (1348392), Derek J. Denhart (2332258)   +2 more
core   +1 more source

Unexpected one-pot formation of the 1H-6a,8a-epiminotricyclopenta[a,c,e][8]annulene system from cyclopentanone, ammonia and dimethyl fumarate. Synthesis of highly strained polycyclic nitroxide and EPR study

Beilstein Journal of Organic Chemistry, 2019
The unexpected formation of a highly strained polycyclic amine was observed in a one-pot synthesis from cyclopentanone, dimethyl fumarate and ammonium acetate.
Sergey A. Dobrynin, Igor A. Kirilyuk, Yuri V. Gatilov, Andrey A. Kuzhelev, Olesya A. Krumkacheva, Matvey V. Fedin, Michael K. Bowman, Elena G. Bagryanskaya   +7 more
doaj   +1 more source

Solvent incorporated sequential [3 + 2] annulation/substitution reaction of azomethine imines and propargyl sulfur ylide

, 2018
A novel three-component, solvent incorporated sequential [3 + 2] cycloaddition/substitution reaction of azomethine imines with propargyl sulfur ylide was developed.
Yanli Yang, Jiangyan Duan, Jinyan Liang, Shoujie Shen, Zhenhu Jia   +4 more
core   +1 more source

Synthesis of fused tricyclic amines unsubstituted at the ring-junction positions by a cascade condensation, cyclization, cycloaddition then decarbonylation strategy

Beilstein Journal of Organic Chemistry, 2012
Heating aldehydes that contain a protected hydroxymethyl group, a tethered alkyl chloride and a tethered alkenyl group at the α-position of the aldehyde with an amine sets up a cascade (tandem) reaction sequence involving condensation to an intermediate ...
Iain Coldham, Adam J. M. Burrell, Hélène D. S. Guerrand, Luke Watson, Nathaniel G. Martin, Niall Oram   +5 more
doaj   +1 more source

A Facile Synthesis of Functionalized Dispirooxindole Derivatives via a Three-Component 1,3-Dipolar Cycloaddition Reaction

Molecules, 2013
An efficient synthesis of novel dispirooxindoles has been achieved through three-component 1,3-dipolar cycloaddition of azomethine ylides generated in situ by the decarboxylative condensation of isatin and an α-amino acid with the dipolarophile 5 ...
Liang Ouyang, Rongsheng Tong, Jianyou Shi, Zhixiang Yuan, Guang Ouyang, Jun He   +5 more
doaj   +1 more source

Straightforward Regio- and Diastereoselective Synthesis, Molecular Structure, Intermolecular Interactions and Mechanistic Study of Spirooxindole-Engrafted Rhodanine Analogs

Molecules, 2021
Straightforward regio- and diastereoselective synthesis of bi-spirooxindole-engrafted rhodanine analogs 5a–d were achieved by one-pot multicomponent [3 + 2] cycloaddition (32CA) reaction of stabilized azomethine ylide (AYs 3a–d) generated in situ by ...
Assem Barakat, Matti Haukka, Saied M. Soliman, M. Ali, Abdullah Mohammed Al-Majid, Ayman El-Faham, Luis R. Domingo   +6 more
doaj   +1 more source

Approach to the Homoerythrina Alkaloids Using a Tandem N-Alkylation/Azomethine Ylide Cycloaddition

, 2016
Synthetic efforts toward the homoerythrina alkaloids 1−3 are described. Two separate model systems guided the pivotal [3 + 2] azomethine ylide cycloaddition cascade to form the A−C rings of these alkaloids.
Jeff W. Kampf (1537393), Jeffrey E. Kropf (1811143), Ill Young Lee (2490805), William H. Pearson (2490808), Allison L. Choy (2465482)   +4 more
core   +4 more sources

Enabling Cross‐Coupling Reactivity of α‐Pentafluorosulfanyl Compounds with a Thermally Stable Organozinc α‐SF5 Reagent

Chemistry – A European Journal, EarlyView.
This work describes the first example of a thermally stable α‐SF5 organometallic reagent, which allows for extensive downstream functionalization by allylation and acylation reactions under copper catalysis, as well as palladium‐catalyzed Negishi‐type cross‐coupling conditions up to 96% yield. In silico analysis shines initial light on the requirements
Lujie Xu, David Rombach
wiley   +1 more source

Multicomponent synthesis, biological evaluation and molecular docking of new spiro-oxindole derivatives

Journal of Taibah University for Science, 2017
A new series of spiro-oxindoles that were identified based upon their ability to inhibit methionine tRNA synthase (PDB ID: 1PFV) and glucosamine-6-phosphate synthase (PDB ID: 1JXA) enzymes in virtual screening was synthesized by a three-component 1,3 ...
M. Sapnakumari, B. Narayana, K.S. Shashidhara, B.K. Sarojini   +3 more
doaj   +1 more source

Impact of polymer aging on main‐chain poly(fullerene)s with halide chain‐ends for inverted perovskite solar cells

Polymer International, EarlyView.
Subtle variations in halogen chemistry significantly affect the aging behavior of polymeric electron transport layers in inverted perovskite solar cells, underscoring the importance of precise chemical design for enhancing long‐term stability. Abstract As perovskite solar cells (PSCs) advance toward commercialization, the need for stable and easily ...
João V. Paulin, Gabriel L. Nogueira, Douglas H. N. Santos, Marco Antônio G. B. Gomes, Valdemiro P. Carvalho‐Jr, Luiz C. Silva Filho, Roger C. Hiorns, Carlos F. O. Graeff   +7 more
wiley   +1 more source