Results 51 to 60 of about 32,578 (240)

Synthesis of spiropyrrolizidines containing quinoxaline and pyrrole fragments [PDF]

Известия Саратовского университета. Новая серия: Серия Химия. Биология. Экология, 2023
The reaction of 1,3-dipolar cycloaddition azomethine ylides obtained by the in situ interaction of 11H-indeno[1,2-b]quinoxalin-11-one and proline, and 3-phenyl-1-pyrrolyl-2-en-1-ones has been used for the synthesis of substituted spiropyrrolizidines in ...
Borisova, Svetlana Vasilievna, Sorokin, Vitaly Viktorovich, Klochkova, Irina N.   +2 more
doaj   +1 more source

Metal-free α-amination of secondary amines: computational and experimental evidence for azaquinone methide and azomethine ylide intermediates. [PDF]

J Org Chem, 2013
We have performed a combined computational and experimental study to elucidate the mechanism of a metal-free α-amination of secondary amines. Calculations predicted azaquinone methides and azomethine ylides as the reactive intermediates and showed that ...
Dieckmann A, Richers MT, Platonova AY, Zhang C, Seidel D, Houk KN.   +5 more
europepmc   +2 more sources

Stereoselective synthesis of fused tetrahydroquinazolines through one-pot double [3 + 2] dipolar cycloadditions followed by [5 + 1] annulation

Beilstein Journal of Organic Chemistry, 2016
The one-pot [3 + 2] cycloaddition of an azomethine ylide with a maleimide followed by another [3 + 2] cycloaddition of an azide with the second maleimide gives a 1,5-diamino intermediate which is used for a sequential aminomethylation reaction with ...
Xiaofeng Zhang, Kenny Pham, Shuai Liu, Marc Legris, Alex Muthengi, Jerry P. Jasinski, Wei Zhang   +6 more
doaj   +1 more source

Synthesis and Characterization of New Spirooxindoles Including Triazole and Benzimidazole Pharmacophores via [3+2] Cycloaddition Reaction: An MEDT Study of the Mechanism and Selectivity

Molecules, 2023
A new series of spirooxindoles based on benzimidazole, triazole, and isatin moieties were synthesized via a [3+2] cycloaddition reaction protocol in one step. The single X-ray crystal structure of the intermediate triazole-benzimidazole 4 was solved. The
Saeed Alshahrani, Abdullah Mohammed Al-Majid, Abdullah Saleh Alamary, M. Ali, Mezna Saleh Altowyan, Mar Ríos-Gutiérrez, Sammer Yousuf, Assem Barakat   +7 more
doaj   +1 more source

An Azomethine Ylide Approach to Complex Alkaloid-like Heterocycles [PDF]

The Journal of Organic Chemistry, 2007
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
William V, Murray, David, Francois, Amy, Maden, Ignatius, Turchi   +3 more
openaire   +2 more sources

Synthesis of Spirocyclic Amines by 1,3-Dipolar Cycloaddition of Azomethine Ylides and Azomethine Imines [PDF]

Synthesis, 2020
Simple ketone starting materials with a halide leaving group and an alkene were prepared in one step and heated with glycine or glycine esters to promote a tandem imine formation, cyclization, and dipolar cycloaddition cascade. The chemistry was also feasible with acetylhydrazide.
Choi, A., Castle, J., Saruengkhanphasit, R., Coldham, I.   +3 more
openaire   +2 more sources

Triethylamine-Promoted Oxidative Cyclodimerization of 2H-Azirine-2-carboxylates to Pyrimidine-4,6-dicarboxylates: Experimental and DFT Study

Molecules, 2023
An unprecedented oxidative cyclodimerization reaction of 2H-azirine-2-carboxylates to pyrimidine-4,6-dicarboxylates under heating with triethylamine in air is described. In this reaction, one azirine molecule undergoes formal cleavage across the C-C bond
Timofei N. Zakharov, Pavel A. Sakharov, Mikhail S. Novikov, Alexander F. Khlebnikov, Nikolai V. Rostovskii   +4 more
doaj   +1 more source

Ethyl 1-benzyl-1,2,3,3a,4,10b-hexahydropyrrolo[2′,3′:3,4]pyrrolo[1,2-a]benzimidazole-2-carboxylate

Acta Crystallographica Section E, 2011
The title molecule, C22H23N3O2, was obtained via an intramolecular cycloaddition of an azomethine ylide and an alkene tethered by a benzimidazole unit. The benzoimidazole unit is essentially planar, with an r.m.s. deviation of 0.0087 Å
Liping Meng, James C. Fettinger, Mark J. Kurth   +2 more
doaj   +1 more source

Synthesis of pyrrolo[1,2-a]quinolines by formal 1,3-dipolar cycloaddition reactions of quinolinium salts

Beilstein Journal of Organic Chemistry, 2019
Quinolinium salts, Q+-CH2-CO2Me Br− and Q+-CH2-CONMe2 Br− (where Q = quinoline), were prepared from quinolines. Deprotonation of these salts with triethylamine promoted the reaction of the resulting quinolinium ylides (formally azomethine ylides) with ...
Anthony Choi, Rebecca M. Morley, Iain Coldham   +2 more
doaj   +1 more source

β-Lactam-Based Azomethine Ylide Reactivity. Expedient Synthesis of Carbapenams and Carbapenems

, 2016
β-Lactam-Based Azomethine Ylide Reactivity.
Timothy Gallagher (1261572), Sarah R. Martel (2999676), Mary F. Mahon (1293876), Richard Wisedale (2999679), Lee D. Hall (2999673), Neil J. Hales (2694514), Robert H. Bradbury (1730791)   +6 more
core   +1 more source