Results 1 to 10 of about 25,799 (236)

Photocarboxylation of Arylated 2H‐Azirines Exploiting Continuous Flow Technology

European Journal of Organic Chemistry, Volume 28, Issue 18, May 23, 2025.
An efficient continuous process for the synthesis of trisubstituted oxazoles is reported which links the photochemical opening of azirines and the subsequent trapping of the azomethine ylides with CO2 gas. This highlights challenges and solutions when incorporating CO2 as a feedstock material for the photochemical synthesis of small heterocyclic ...
Arlene Bonner, Jorge García‐Lacuna, Marcus Baumann   +2 more
wiley   +1 more source

Diastereodivergent Asymmetric 1,3-Dipolar Cycloaddition of Azomethine Ylides and β-Fluoroalkyl Vinylsulfones: Low Cu(II) Catalyst Loading and Theoretical Studies.

Angewandte Chemie, 2019
We have developed Cu(II)-catalyzed asymmetric 1,3-dipolar cycloadditions using β-fluoroalkyl alkenyl arylsulfones as dipolarophiles and glycine/alanine iminoesters as azomethine ylide precursors.
Feng Cheng, S. J. Kalita, Zhen‐Ni Zhao, Xing Yang, Yan Zhao, U. Schneider, N. Shibata, Yiyong Huang   +7 more
semanticscholar   +1 more source

Computational Design, Synthesis, and Biological Assessment of Some Pyrrolo[3,4‐c]Pyrroles Targeting Mycobacterium Tuberculosis

ChemistrySelect, Volume 10, Issue 17, May 5, 2025.
A new set of spirooxindole‐ and spiroindenoquinoxaline‐derived pyrrolo[3,4‐c] pyrroles has been synthesized through atom‐economic one‐pot multicomponent reactions. Based on the results, compounds 4b and 5a demonstrated promising Glide scores and exhibited strong binding affinity with decaprenylphosphoryl‐β‐D‐ribofuranose oxidoreductase.
Mathiyazhagan Lavanya, Rajamanikandan Sundararaj, Kailasam Saravana Mani, Krishnakumar Balu, Mani Durai, Perwez Alam, Priya SD, Mathivanan Durai, Young Ho Ahn   +8 more
wiley   +1 more source

Recent Advancements in the Cyclization Strategies of 1,3‐Enynes Towards the Synthesis of Heterocyclic/Carbocyclic Frameworks

Chemistry – An Asian Journal, Volume 20, Issue 8, April 17, 2025.
In this review, the advancements in the cyclization of 1,3‐enynes to construct structurally diverse heterocyclic and carbocyclic frameworks are portrayed comprehensively. Divergent cyclization protocols along with mechanistic aspects for key transformations are also detailed. Abstract 1,3‐Enynes have demonstrated their utility as valuable precursors to
Akash P. Sakla, Shams Aaghaz, Shujauddin Ahmed, Naziya Neshat, Ahmed Kamal   +4 more
wiley   +1 more source

Highly Efficient Asymmetric [3+2] Cycloaddition Promoted by Chiral Aziridine-Functionalized Organophosphorus Compounds

Molecules
The asymmetric [3+2] cycloaddition of azomethine ylides generated from the corresponding imino ester-to-trans-β-nitrostyrene catalysis by chiral aziridine-containing phosphines and phosphine oxides is described. Of the sixteen stereoisomers that could be
Julia Szymańska, Michał Rachwalski, Adam M. Pieczonka   +2 more
doaj   +1 more source

Addition of azomethine ylides to carbon-encapsulated iron nanoparticles

Dalton Transactions, 2018
Carbon-encapsulated iron nanoparticles have been covalently functionalized using the Prato reaction.
Artur Kasprzak, Anna M. Nowicka, Jakub P. Sek, Maciej Fronczak, Michał Bystrzejewski, Mariola Koszytkowska-Stawinska, Magdalena Poplawska   +6 more
openaire   +4 more sources

Multicomponent synthesis, biological evaluation and molecular docking of new spiro-oxindole derivatives

Journal of Taibah University for Science, 2017
A new series of spiro-oxindoles that were identified based upon their ability to inhibit methionine tRNA synthase (PDB ID: 1PFV) and glucosamine-6-phosphate synthase (PDB ID: 1JXA) enzymes in virtual screening was synthesized by a three-component 1,3 ...
M. Sapnakumari, B. Narayana, K.S. Shashidhara, B.K. Sarojini   +3 more
doaj   +1 more source

Electron-rich benzofulvenes as effective dipolarophiles in copper(i)-catalyzed asymmetric 1,3-dipolar cycloaddition of azomethine ylides. [PDF]

Chem Sci, 2023
Chang X, Liu XT, Li F, Yang Y, Chung LW, Wang CJ.   +5 more
europepmc   +1 more source

Copper(I)-Catalyzed Asymmetric 1,3-Dipolar Cycloaddition of Azomethine Ylides with Fluorinated Imines: The Expanded Scope and Mechanism Insights.

Journal of Organic Chemistry, 2018
The mechanism of the Cu(I)/( S, Rp)-PPFOMe-catalyzed 1,3-dipolar cycloaddition of azomethine ylides with fluorinated aldimines has been studied using labeling experiments, control experiments, and linear effect experiments, which clearly ruled out the 1 ...
Liang Wei, Qing‐Hua Li, Chun‐Jiang Wang   +2 more
semanticscholar   +1 more source

Zinc-Catalyzed Enantioselective [3+2] Cycloaddition of Azomethine Ylides Using Planar Chiral [2.2]Paracyclophane-Imidazoline N,O-ligands. [PDF]

Angew Chem Int Ed Engl, 2022
Kumar SV, Guiry PJ.
europepmc   +1 more source