Results 21 to 30 of about 2,875 (189)

<i>N</i>-Oxide Insertion into LDA Dimeric Aggregates for Azomethine Ylide Formation: Explicit Solvation in Quantum Mechanical Treatment of Polarized Intermediates. [PDF]

J Org Chem
Neal MJ, Chartier EJ, Lane AM, Hejnosz SL, Jesikiewicz LT, Liu P, Rohde JJ, Lummis P, Fox DJ, Evanseck JD, Montgomery TD.   +10 more
europepmc   +3 more sources

Substituted proline derivatives as organocatalysts in Michael reaction [PDF]

Journal of the Serbian Chemical Society, 2014
Chiral, polysubstituted proline esters, obtained via cycloaddition reactions of azomethine ylides, have been studied as organocatalysts in Michael reaction of aldehydes/ketones and vinylsulphones. Under optimised reaction conditions employing 10
Jovanović Predrag, Ranđelović Jelena, Ivković Branka, Suteu Cristina, Tokić-Vujosević Zorana, Savić Vladimir   +5 more
doaj   +1 more source

Intramolecular Cycloaddition of Imines of Cysteine Derivatives

Molecules, 1998
Azomethine ylides were generated from Schiffs bases of S-allylcysteine methyl ester and their intramolecular 1,3-dipolar cycloadditions were studied. These reactions led to the synthesis of thieno[3,4-b]pyrrole derivatives in good yield.
Teresa M. V. D. Pinho e Melo, António M. d'A Rocha Gonsalves, Ana M. T. D. P. V. Cabral   +2 more
doaj   +1 more source

Synthesis of pyrrolo[1,2-a]quinolines by formal 1,3-dipolar cycloaddition reactions of quinolinium salts

Beilstein Journal of Organic Chemistry, 2019
Quinolinium salts, Q+-CH2-CO2Me Br− and Q+-CH2-CONMe2 Br− (where Q = quinoline), were prepared from quinolines. Deprotonation of these salts with triethylamine promoted the reaction of the resulting quinolinium ylides (formally azomethine ylides) with ...
Anthony Choi, Rebecca M. Morley, Iain Coldham   +2 more
doaj   +1 more source

Highly Efficient and Diastereoselective Synthesis of New Pyrazolylpyrrolizine and Pyrazolylpyrrolidine Derivates by a Three-Component Domino Process

Molecules, 2014
Diastereoselective reactions between 4-formylpyrazoles, N-substituted maleimides and glycine derivates led to new series of pyrazolyldipyrrolo [3,4-a:3',4'-f]pyrrolizines and pyrazolylpyrrolo[3,4-c]pyrroles in good yields.
Jairo Quiroga, Jaime Gálvez, Rodrigo Abonia, Braulio Insuasty, Alejandro Ortíz, Justo Cobo, Manuel Nogueras   +6 more
doaj   +1 more source

Design, Synthesis, and Structural Evolution of Pseudo‐Natural Product IDO1 Inhibitors and Degraders

Angewandte Chemie, Volume 138, Issue 3, 16 January 2026.
The combination of bicyclic monoterpene‐ and pyrrolidine‐alkaloid fragments yields novel pseudo‐natural products. Biological characterization revealed that these iDegs are inhibitors and degraders of indoleamine‐2,3‐dioxygenase. Abstract Terpenoid alkaloids are derived from the fusion of structurally diverse terpenoid‐ and alkaloid moieties.
Xiu‐Fen Cheng, Belén Lucas, Philipp Lampe, Stefano Ugel, Suyuan Chen, Anke Unger, Matthias Bischoff, Soheila Rezaei Adariani, Kesava Reddy Naredla, Kamal Kumar, Annika Schmidt, Carsten Strohmann, Petra Janning, Raphael Gasper, María Lucas, Malte Gersch, Sonja Sievers, Vincenzo Bronte, Slava Ziegler, Herbert Waldmann   +19 more
wiley   +2 more sources

Site-Selective Modification of a Porpholactone—Selective Synthesis of 12,13- and 17,18-Dihydroporpholactones

Molecules, 2020
The reaction of meso-tetrakis(pentafluorophenyl)porpholactone with azomethine ylides and nitrones affords pyrrolidine-fused and isoxazolidine-fused dihydroporpholactones that display, respectively, isobacteriochlorin- and chlorin-type UV–Vis spectra ...
Ana F. R. Cerqueira, Gustautas Snarskis, Jonas Zurauskas, Samuel Guieu, Filipe A. Almeida Paz, Augusto C. Tomé   +5 more
doaj   +1 more source

Highly Efficient Construction of Sugar-Fused Spirochromanono Pyrrolidines/Pyrrolizidines/Thiolizidines via 1,3-Dipolar Cycloaddition of Azomethine Ylides

SynOpen, 2017
A variety of sugar-fused chromanono pyrrolidines/pyrrolizidines/thiolizidines have been synthesized by intermolecular 1,3-dipolar cycloaddition reaction of azomethine ylides (generated from glucose aldehyde and different secondary amino acids) with ...
Sirisha Nallamala, Srikumar Mannem, Raghunathan Raghavachary   +2 more
doaj   +1 more source

Enantiomerically Enriched 1,2-P,N-Bidentate Ferrocenyl Ligands for 1,3-Dipolar Cycloaddition and Transfer Hydrogenation Reactions

Molecules, 2018
Novel complexes of 1,2-P,N-bidentate ferrocenyl ligands with AgOAc or with [RuCl2(PPh3)3] as catalysts have been studied in asymmetric synthesis. The catalytic activity of these systems have been studied in [3+2]-cycloaddition of azomethine ylides with ...
Irina A. Utepova, Polina O. Serebrennikova, Marina S. Streltsova, Alexandra A. Musikhina, Tatiana G. Fedorchenko, Oleg N. Chupakhin, Andrey P. Antonchick   +6 more
doaj   +1 more source

Benzotriazolylmethylaminosilanes: Novel azomethine ylide equivalents

Tetrahedron, 1994
Abstract Benzotriazolylmethylaminosilanes, readily accessible from the reaction of benzotriazole, an aldehyde and an (aminomethyl)silane in water at 20°C, are azomethine ylide equivalents which undergo stereospecific cycloadditions with dipolarophiles to give substituted pyrrolidines or 2,5-dihydropyrroles in good yields.
Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, FL 32611-7200 USA ( host institution ), R. Katritzky, Alan, Köditz, Jens, Lang, Hengyuan   +3 more
openaire   +2 more sources