Results 81 to 90 of about 5,623 (241)

1,3-Dipolar Cycloaddition in the Preparation of New Fused Heterocyclic Compounds via Thermal Initiation

Molecules, 2016
This paper describes the synthesis of precursors with a benzo[b]furan skeleton for the intramolecular 1,3-dipolar cycloaddition of azomethine ylides prepared from N-substituted 3-allyl-aminobenzo[b]furan-2-aldehydes and secondary amines derived from α ...
Martin Porubský, Lukáš Tenora, Milan Potáček   +2 more
doaj   +1 more source

Synthesis of benzopyranopyrrolidines via 1,3-dipolar cycloaddition of nonstabilized azomethine ylides with 3-substituted coumarins [PDF]

, 2013
A three-component reaction of 3-substituted coumarins with N-alkyl-α-amino acids and aldehydes gave 1-benzopyrano[3,4-c]pyrrolidines as a result of a 1,3-dipolar cycloaddition of an intermediate nonstabilized azomethine ylide at the double bond of the ...
Moshkin, V. S., Röschenthaler, G.-V., Sosnovskikh, V. Y.   +2 more
core   +1 more source

Computational Design, Synthesis, and Biological Assessment of Some Pyrrolo[3,4‐c]Pyrroles Targeting Mycobacterium Tuberculosis

ChemistrySelect, Volume 10, Issue 17, May 5, 2025.
A new set of spirooxindole‐ and spiroindenoquinoxaline‐derived pyrrolo[3,4‐c] pyrroles has been synthesized through atom‐economic one‐pot multicomponent reactions. Based on the results, compounds 4b and 5a demonstrated promising Glide scores and exhibited strong binding affinity with decaprenylphosphoryl‐β‐D‐ribofuranose oxidoreductase.
Mathiyazhagan Lavanya, Rajamanikandan Sundararaj, Kailasam Saravana Mani, Krishnakumar Balu, Mani Durai, Perwez Alam, Priya SD, Mathivanan Durai, Young Ho Ahn   +8 more
wiley   +1 more source

Copper-Catalyzed Asymmetric Dearomative [3+2] Cycloaddition of Nitroheteroarenes with Azomethines

Molecules, 2023
Catalytic asymmetric dearomative [3+2] cycloaddition of α-imino γ-lactones with either 3-nitroindoles or 2-nitrobenzofurans by using a chiral copper complex as the catalyst was developed.
Yan Chen, Jian-Qiang Zhao, Yan-Ping Zhang, Ming-Qiang Zhou, Xiao-Mei Zhang, Wei-Cheng Yuan   +5 more
doaj   +1 more source

Alkaloidszármazékok szintézise = Synthesis of alkaloid derivatives [PDF]

, 2009
a) Elsőként alkalmaztunk 3-nitrokromén-származékokat 2 pi komponensként azometin-ilidek 1,3-dipoláris cikloaddíciójában b) Új, egyedényes eljárást dolgoztunk ki hexahidro-pirrolo[2,1-a]izokinolinok előállítására c) Új azepin gyűrűt tartalmozó ...
Nyerges, Miklós, Pintér, Áron, Toke, László, Virányi, Andrea   +3 more
core  

Asymmetric metal-catalyzed [3+2] cycloadditions of azomethine ylides [PDF]

, 2006
Cycloadditions of azomethine ylides with olefins provide a short, attractive route to pyrrolidine units with the potential to control the relative and absolute configuration by means of a chiral catalyst.
Stohler, Remo
core   +1 more source

Organic Transformations Utilizing 1,5,7‐Triazabicyclo[4.4.0]Dec‐5‐Ene (TBD): A Tale of Two Nitrogens

European Journal of Organic Chemistry, Volume 28, Issue 12, March 24, 2025.
1,5,7‐Triazabicyclo[4.4.0]dec‐5‐ene (TBD) is a bicyclic guanidine that has drawn considerable attention in organic synthesis. Its multifunctionality and versatility makes it an ideal reagent to promote various reactions. This review provides a concise guide to recent developments and organic transformations utilizing TBD, classified by the primary ...
Chunling Blue Lan, Karine Auclair
wiley   +1 more source

Synthesis of bis-spirocyclic derivatives of 3-azabicyclo[3.1.0]hexane via cyclopropene cycloadditions to the stable azomethine ylide derived from Ruhemann's purple

Beilstein Journal of Organic Chemistry, 2022
A reliable method for the synthesis of bis-spirocyclic derivatives of 3-azabicyclo[3.1.0]hexanes through the 1,3-dipolar cycloaddition (1,3-DC) reactions of cyclopropenes to the stable azomethine ylide – protonated form of Ruhemann's purple (PRP) has ...
Alexander S. Filatov, Olesya V. Khoroshilova, Anna G. Larina, Vitali M. Boitsov, Alexander V. Stepakov   +4 more
doaj   +1 more source

Binap-silver-catalyzed enantioselective multicomponent 1,3-dipolar cycloaddition of azomethines ylides derived from ethyl glyoxylate [PDF]

, 2015
The enantioselective binap–silver catalyzed multicomponent 1,3-dipolar cycloaddition using ethyl glyoxylate, phenylalanine ethyl ester, and maleimides is described. The employment of basic silver carbonate allows the reaction to take place in the absence
Mancebo Aracil, Juan, Nájera, Carmen, Sansano, Jose M.   +2 more
core   +2 more sources

2‐Aminoindoles and 2‐Iminoindolines as Viable Precursors of Indole‐Fused Nitrogenated Polyheterocycles

Advanced Synthesis &Catalysis, Volume 367, Issue 6, March 18, 2025.
Abstract The synthesis of architecturally complex polyheterocyclic structures embedding the indole ring represents a growing field of interest. Carbolines and their partially dehydro derivatives, pyrazinoindoles, indoloindoles, azepinoindoles and other medium‐sized derivatives are only some examples of indole‐containing polycyclic compounds featured by
Alessandro Palmieri, Marino Petrini
wiley   +1 more source