Results 111 to 120 of about 15,703 (232)

Brewers' rice attenuated aberrant crypt foci developing in colon of azoxymethane-treated rats [PDF]

, 2016
Brewers' rice is one of abundant agricultural waste products in the rice industry. The present study is designed to investigate the potential of brewers' rice to inhibit the development of aberrant crypt foci (ACF) in colon of azoxymethane (AOM)-treated ...
Ashok Kumar, Pandurangan, Hamzah, Hazilawati, Karim, Roselina, Mohd Esa, Norhaizan, Tan, Bee Ling   +4 more
core  

Inflammation mobilizes copper metabolism to promote colon tumorigenesis via an IL-17-STEAP4-XIAP axis. [PDF]

, 2020
Copper levels are known to be elevated in inflamed and malignant tissues. But the mechanism underlying this selective enrichment has been elusive. In this study, we report a axis by which inflammatory cytokines, such as IL-17, drive cellular copper ...
Bao, Shideng, Bulek, Katarzyna, Cai, Gang, Chang, Christopher J, Chen, Xing, Fox, Paul L, Huang, Emina, Jackson, Mark W, Jia, Shang, Kalady, Matthew F, Li, Xiaoxia, Liao, Yun, Pizarro, Theresa T, Sen, Ganes C, Stark, George R, Tang, Fangqiang, Zhao, Junjie   +16 more
core  

Determination of Rottlerin, a Natural Protein Kinases C Inhibitor, in Pancreatic Cancer Cells and Mouse Xenografts by RP-HPLC Method. [PDF]

, 2013
Rottlerin is a natural polyphenolic ketone isolated from the pericarps of Mallotus phillippinensis. In previous studies we showed that parenteral administration of rottlerin reduced tumor growth in murine xenograft models of pancreatic cancer. The aim of
Edderkaoui, Mouad, Eibl, Guido, Go, Vay-Liang, Lu, Qing-Yi, Lugea, Aurelia, Moro, Aune, Pandol, Stephen, Zhang, Lifeng   +7 more
core   +1 more source

Repercussão hepática da carcinogênese colorretal induzida pelo azoximetano Hepatic repercussions of azoxymethane-induced colorectal carcinogenesis

Revista do Colégio Brasileiro de Cirurgiões, 2013
OBJETIVO: Avaliar as repercussões hepáticas da carcinogênese colônica induzida por diferentes doses e tempos de exposição ao azoximetano em ratos Wistar. MÉTODOS: Quarenta e quatro ratos foram distribuídos em quatro grupos. Os animais tinham oito semanas
Idália Maria Brasil Burlamaqui, Conceição Aparecida Dornelas, Paulo Roberto Carvalho Almeida, Francisco Vagnaldo Fechine Jamacaru, Daniel Magalhães Coutinho Mota, Francisco José Cabral Mesquita, Lara Albuquerque de Brito, Lara Burlamaqui Veras, Lusmar Veras Rodrigues   +8 more
doaj  

Wild cherry (Prunus microcarpa) ameliorates azoxymethane-induced aberrant crypt foci in vivo: Depicted molecular mechanisms

ARO-The Scientific Journal of Koya University
Colorectal cancer is the third diagnosed cancer across the globe despite modern therapeutic interventions. Prunus microcarpa has been consumed as a therapeutic tea for several human disorders; therefore, the study investigates the chemoprotective ...
Ahmed A. Abduljabbar, Parween A. Ismail
doaj   +1 more source

Comparing the effects of COX and non-COX-inhibiting NSAIDs on enhancement of apoptosis and inhibition of aberrant crypt foci formation in a rat colorectal cancer model [PDF]

, 2013
The protection against colorectal cancer (CRC) by non-steroidal anti-inflammatory drugs (NSAIDs) is in part dependent on inhibition of cyclooxygenase (COX).
Hu, Ying, Le Leu, Richard Kevin, Martin, Jonathan Edward, Young, Graeme Paul   +3 more
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Méta-analyse des effets de l’oligofructose et de l’inuline sur le risque de cancer colorectal dans deux modèles murins : rats traités par un carcinogène et souris Min [PDF]

, 2008
Le cancer colorectal est l’une des principales causes de mortalité dans le monde. De nombreuses expérimentations sont menées pour étudier les effets chémo-préventifs de différentes substances présentes dans l’alimentation, notamment l’inuline et l ...
Tournié, Johanne
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Evaluation of Nanocarrier Targeted Drug Delivery of Capecitabine-PAMAM Dendrimer Complex in a Mice Colorectal Cancer Model

Acta Medica Iranica, 2016
Capecitabine, an effective anticancer drug in colorectal cancer chemotherapy, may create adverse side effects on healthy tissues. In the present study, we first induced colon adenocarcinoma with azoxymethane, a carcinogen agent, and then investigated the
Fatemeh Nabavizadeh, Hafseh Fanaei, Alireza Imani, Jalal Vahedian, Fahimeh Asadi Amoli, Jamal Ghorbi, Hamid Sohanaki, Seyed Mehdi Mohammadi, Ravieh Golchoobian   +8 more
doaj  

Morphometric investigation of the effects of Azoxymethane, Diallyl disulfide and corn oil use on humerus and femur development in rats

Revista Científica
The study aimed to examine the effects of Azoxymethane (AOM), Diallyl Disulfide (DADS), and corn oil on the humerus and femur in rats. In the study, 40 male Wistar Albino rats, 12 weeks old, were used. The animals were divided into four different groups
Sedat Aydoğdu
doaj   +1 more source

5-Methylcoumarin-4β-glucoside mitigated colon tumor progression in mice with AOM/DSS-induced colon carcinogenesis

Phytomedicine Plus
Context: The in vitro cytotoxicity profile of 5-Methylcoumarin-4β-glucoside (5-MC4βG) has been demonstrated to inhibit the proliferation of HT-29 adenocarcinoma cells. Aim: The need for newer and affordable chemotherapeutic agents is critical.
Ibrahim Malami, Alhassan Muhammad Alhassan, Qamar Uddin Ahmed, Syed Adnan Ali Shah, Mohammed Umar, Muhammad Salisu Abubakar, Mustapha Umar Imam, Bilyaminu Abubakar   +7 more
doaj   +1 more source