Results 81 to 90 of about 15,583 (213)

The role of intestinal microflora and probiotic bacteria in prophylactic and development of colorectal cancer [PDF]

, 2013
The gut microbiota comprises a large and diverse range of microorganisms whose activities have a significant impact on health. It interacts with its host at both the local and systemic level, resulting in a broad range of beneficial or detrimental ...
Dagmara Złotkowska, Ewa Wasilewska, Mariola E. Pijagin   +2 more
core   +1 more source

Deciphering Pigmented Rice Varieties as Sustainable and Unexplored Valuable Sources of Bioactive Components With Health‐Related Properties and Technological Applications—A Systematic Review

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 1, January 2026.
ABSTRACT The interest in pigmented grains has grown substantially in recent years. Pigmented rice is crucial for diversifying agricultural production and promoting healthier, more balanced diets. This systematic review updates and discusses literature published between 2019 and 2024 on the bioactive compounds in pigmented rice, their potential health ...
Adolfo Pinheiro de Oliveira, Thatyane Mariano Rodrigues de Albuquerque, Evandro Leite de Souza   +2 more
wiley   +1 more source

Endogenous N-nitroso compounds, and their precursors, present in bacon, do not initiate or promote aberrant crypt foci in the colon of rats [PDF]

, 2000
Processed meat intake is associated with increased risk of colorectal cancer. This association may be explained by the endogenous formation of N-nitroso compounds (NOC).
Corpet, Denis E., Parnaud, Géraldine, Peiffer, Ginette, Pignatelli, Brigitte, Taché, Sylviane   +4 more
core   +1 more source

Microencapsulated Quercetin and Bifidobacterium animalis Independently Preserve Jejunal Enteric Neurons During Colorectal Carcinogenesis

Neurogastroenterology &Motility, Volume 38, Issue 1, January 2026.
Our study explores the impact of colorectal carcinogenesis on jejunal neurons of the enteric nervous system (ENS), revealing significant neuronal damage. We demonstrated that treatments with microencapsulated quercetin and Bifidobacterium animalis protect enteric neuronal density, and this is reflected in improved gastrointestinal transit times.
Lucas Casagrande, Carla Cristina de Oliveira Bernardo, Sabrina Silva Sestak, Maysa Pacheco Alvarez da Silva, Marcos Yudi Nagaoka Godoy, Jean‐Pierre Timmermans, Cesar Agostinho Ferreira, Tânia Cristina Alexandrino Becker, Erick Guilherme Stoppa, Waldiceu Aparecido Verri, José Ricardo de Arruma Miranda, Juliana Vanessa Colombo Martins Perles, Jacqueline Nelisis Zanoni   +12 more
wiley   +1 more source

Polyethylene glycol and prevalence of colorectal adenomas : Population-based study of 1165 patients undergoing colonoscopy [PDF]

, 2006
Background and aim — Dietary polyethylene glycol (PEG) is extraordinarily potent in the chemoprevention of experimental colon carcinogenesis. PEG is used to treat constipation in France and in the USA. French laxatives include Forlax® (PEG4000), Movicol®
Barbieux, Jean-Pierre, Bertrand, Philippe, Bougnoux, Philippe, Brondin, Brigitte, Corpet, Denis E., Dorval, Etienne, Jankowski, Jean Marie, Viguier, Jérôme   +7 more
core  

A Comprehensive Review of AIM2 in Cancer: Functional Roles, Molecular Pathways, and Clinical Relevance

Journal of Immunology Research, Volume 2026, Issue 1, 2026.
Inflammation has been recognized as a component of cancer progression, and inflammasome receptor components also regulate various biological processes, including cell proliferation, gene transcription, and tumorigenesis. Accumulating evidence indicates that the AIM2 inflammasome influences tumor progression via multiple concurrent mechanisms, one of ...
Nuo Wang, Shaoxian Wu, Zhang Fang, Lujun Chen, Xiao Zheng, Poorani Gurumallesh   +5 more
wiley   +1 more source

Dark Aberrant Crypt Foci with activated Wnt pathway are related to tumorigenesis in the colon of AOM-treated rat

Journal of Experimental & Clinical Cancer Research, 2008
Background To evaluate the relationship between Aberrant Crypt Foci (ACF) and tumorigenesis, we observed the sequential development from ACF to tumor in the colon of azoxymethane-exposed wistar rats. Methods Sixty wistar rats were sacrificed at different
Lin Chen, Jiang Bo, Lu Qing, Shan Tao
doaj   +1 more source

Multitargeted Low-Dose GLAD Combination Chemoprevention: A Novel and Promising Approach to Combat Colon Carcinogenesis [PDF]

, 1967
Preclinical studies have shown that gefitinib, licofelone, atorvastatin, and α-difluoromethylornithine (GLAD) are promising colon cancer chemopreventive agents.
Altaf Mohammed, Naveena B Janakiram, Misty Brewer, Krishna Vedala, Vernon E Steele, Chinthalapally V Rao, Ferlay, Half, Moser, Preston, Corpet, Reddy, Reddy, Kawamori, Swamy, Rao, Bertagnolli, Mohammed, Janakiram, Perez, Lao, Zhou, Gerner, Suh, Sporn, Frei, Nigro, Li, Zell, Ignatenko, Meyskens, Reddy, Ali, Narisawa, Narisawa, Poynter, Sacks, Pederson, Agarwal, Swamy, Shaw, Gavert, Baselga, Jacoby, Erdman, Yerushalmi, Dougherty, Kaminska, Ueda, Giles, Harris, Fantini, Akagi, Petersen, Lee   +54 more
core   +2 more sources

RNA m1A methyltransferase TRMT61A promotes colorectal tumorigenesis by enhancing ONECUT2 mRNA stability and is a potential therapeutic target

Cancer Communications, Volume 45, Issue 12, Page 1616-1644, December 2025.
Abstract Background The role of N1‐methyladenosine (m1A) in cancer is poorly understood. Here we explored the function of RNA methyltransferase TRNA methyltransferase 61A (TRMT61A) in colorectal cancer (CRC) and its potential as a therapeutic target. Methods RNA m1A levels were assessed through liquid chromatography‐mass spectrometry.
Xiaoting Zhang, Na Qin, Fenfen Ji, Hao Su, Haiyun Shang, Hongyan Chen, Dan Huang, Qing Li, Jing Ren, Weixin Liu, Yifei Wang, Wei Kang, Jiabin Wu, Chi‐Chun Wong, Zongwei Cai, Matthew Tak Vai Chan, William Ka Kei Wu, Jun Yu, Huarong Chen   +18 more
wiley   +1 more source

Preventive Effects of Resveratrol against Azoxymethane Induced Damage in Rat Liver

Asian Pacific Journal of Cancer Prevention, 2013
In recent years, due to modern lifestyles and exposure to chemical carcinogens, cancer cases are steadily increasing. From this standpoint, azoxymethane (AOM), a chemical carcinogen which causes de novo liver damage, and resveratrol, which is an antioxidant found in foods and protects against oxidative stress damage, are of interest.
Gürocak S., Karabulut E., Karadag N., Ozgor D., Ozkeles N., Bay Karabulut A.   +5 more
openaire   +5 more sources