Results 71 to 80 of about 15,703 (232)

Discovery of cancer-preventive juices reactivating RB functions

Environmental Health and Preventive Medicine, 2023
Background: Recent advances have been achieved in the genetic diagnosis and therapies against malignancies due to a better understanding of the molecular mechanisms underlying carcinogenesis.
Mitsuharu Masuda, Mano Horinaka, Shusuke Yasuda, Mie Morita, Emi Nishimoto, Hideki Ishikawa, Michihiro Mutoh, Toshiyuki Sakai   +7 more
doaj   +1 more source

Inulin‐Based Oral Chemotherapy Modulates Gut Microbiota and Immune Microenvironment through Inhibition of Neutrophil Extracellular Trap Formation for Improving Cancer Therapy

Advanced Science, Volume 13, Issue 20, 9 April 2026.
Schematic representation of ZIF‐8@OXA@inulin for cancer immunotherapy. Synthesis of ZIF‐8@OXA@inulin. Augmentation of pyroptosis, regulation of gut microbiota, and inhibition of NETs formation by ZIF‐8@OXA@inulin‐mediated comprehensive strategy for antitumor immune response. ABSTRACT Despite the potential of chemoimmunotherapy against colorectal cancer
Zhenhao Li, Jiaqiang Jiang, Yuping Zhou, Xinyuan Mao, Haotian Wen, Zhian Chen, Yutong Wang, Cong Huang, Yanfeng Hu   +8 more
wiley   +1 more source

Bifidobacterium animalis ssp. lactis BX-245-fermented milk alleviates tumor burden in mice with colorectal cancer

Journal of Dairy Science
: Colorectal cancer (CRC) arises from the accumulation of abnormal mutations in colorectal cells during prolonged inflammation. This study aimed to investigate the potential of probiotic fermented milk containing the probiotic strain, Bifidobacterium ...
Chengcong Yang, Musu Zha, Lu Li, Jiaqi Qiao, Lai-Yu Kwok, Dandan Wang, Yongfu Chen   +6 more
doaj   +1 more source

Colon cancer chemoprevention by sage tea drinking: decreased DNA damage and cell proliferation [PDF]

, 2016
Salvia officinalis and some of its isolated compounds have been found to be preventive of DNA damage and increased proliferation in vitro in colon cells. In the present study, we used the azoxymethane model to test effects of S.
Baltazar, Fátima, Lima, Cristóvão Fernando Macedo, Pedro, Dalila F. N., Ramos, Alice Fernanda Abreu, Wilson, Cristina Pereira   +4 more
core   +1 more source

Targeting SLC5A2 suppresses colorectal tumour development by enhancing NK cell activity through extracellular vesicle‐dependent MICA/B signalling

Clinical and Translational Medicine, Volume 16, Issue 4, April 2026.
SLC5A2 modulates the membrane potential and calcium influx, enhancing MHC‐I‐associated MICA/B secretion via extracellular vesicle (EV) formation and thereby enabling CRC cells to evade NK cell surveillance. Our findings reveal the critical role of SLC5A2 in CRC progression and suggest dapagliflozin, a clinically approved sodium‒glucose cotransporter 2 (
Jun Xiao, Jianghua Wu, Fengliu Deng, Chaoqun Liu, Yuanhang Chen, Ke Shen, Chuangyuan Wang, Wandie Lin, Weiwei Liu, Ziyan Ning, Rui Zhou, Liang Zhao   +11 more
wiley   +1 more source

Point: From animal models to prevention of colon cancer. Systematic review of chemoprevention in min mice and choice of the model system. [PDF]

, 2003
The Apc(Min/+) mouse model and the azoxymethane (AOM) rat model are the main animal models used to study the effect of dietary agents on colorectal cancer. We reviewed recently the potency of chemopreventive agents in the AOM rat model (D. E.
Corpet, Denis E., Pierre, Fabrice
core   +2 more sources

Suppression of β-catenin and cyclooxygenase-2 expression and cell proliferation in azoxymethane-induced colonic cancer in rats by rice bran phytic acid (PA) [PDF]

, 2013
Background: Phytic acid (PA) is a polyphosphorylated carbohydrate that can be found in high amounts in mostcereals, legumes, nut oil, seeds and soy beans. It has been suggested to play a significant role in inhibition of colorectal cancer. This study was
Ithnin, Hairuszah, Mohd Esa, Norhaizan, Saad, Norazalina   +2 more
core   +1 more source

Enhanced Development of Azoxymethane-Induced Colonic Preneoplastic Lesions in Hypertensive Rats [PDF]

International Journal of Molecular Sciences, 2013
Metabolic syndrome is associated with an increased risk of colorectal cancer. This study investigated the impact of hypertension, a component of metabolic syndrome, on azoxymethane (AOM)-induced colorectal carcinogenesis using SHRSP/Izm (SHRSP) non-diabetic/hypertensive rats and SHRSP.Z-Leprfa/IzmDmcr (SHRSP-ZF) diabetic/hypertensive rats.
Kochi, Takahiro, Shimizu, Masahito, Ohno, Tomohiko, Baba, Atsushi, Sumi, Takafumi, Kubota, Masaya, Shirakami, Yohei, Tsurumi, Hisashi, Tanaka, Takuji, Moriwaki, Hisataka   +9 more
openaire   +2 more sources

Natural Remedies for Gut Health: The Role of Plant Extracts in Combating Inflammatory Bowel Disease and Colon Cancer

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
Created in BioRender. Haralambie, O. (2025) https://BioRender.com/dh5ly89. ABSTRACT Digestive disorders such as inflammatory bowel disease (IBD) and colorectal cancer are among the most significant global health challenges, largely driven by chronic inflammation and oxidative stress.
Oana‐Roxana Haralambie, Sanda Andrei
wiley   +1 more source

Helminths as architects of trained tolerance: implications for human health

Clinical &Translational Immunology, Volume 15, Issue 3, 2026.
Abstract Helminths infect nearly 2 billion people worldwide and are a major cause of chronic morbidity in low‐resource regions. Unlike bacterial and viral pathogens that elicit protective memory, helminths actively remodel host immunity to enable their years‐long persistence and reinfection.
Quinn Moroz, Jorge Lucas Nascimento Souza, Neima Briggs   +2 more
wiley   +1 more source