Results 71 to 80 of about 8,111 (184)

Preventive Effects of Resveratrol against Azoxymethane Induced Damage in Rat Liver

Asian Pacific Journal of Cancer Prevention, 2013
In recent years, due to modern lifestyles and exposure to chemical carcinogens, cancer cases are steadily increasing. From this standpoint, azoxymethane (AOM), a chemical carcinogen which causes de novo liver damage, and resveratrol, which is an antioxidant found in foods and protects against oxidative stress damage, are of interest.
Gürocak S., Karabulut E., Karadag N., Ozgor D., Ozkeles N., Bay Karabulut A.   +5 more
openaire   +5 more sources

Mda level in colon tissue of the rats with colon cancer model treated with diallyl disulfide [PDF]

Eurasian Journal of Veterinary Sciences
Aim: This study was conducted to investigate the effect of diallyl disulfide, one of the bioactive compounds of garlic, on the malondialdehyde level of colon tissue in rats with azoxymethane-induced colon cancer. Materials and Methods: A total of 58 male
Beyza Suvarikli Alan, Zafer Bulut
doaj  

Hepatic repercussions of azoxymethane-induced colorectal carcinogenesis.

Revista do Colegio Brasileiro de Cirurgioes, 2014
To evaluate the hepatic effects of colonic carcinogenesis induced by azoxymethane at different doses and times of exposure in rats.Forty-four Wistar rats were divided into four groups. The animals were eight weeks at the beginning of the experiment. group 1 received 1.0 ml of saline intraperitoneally once a week for two weeks. Group 2 received 15 mg/kg
Idália Maria Brasil, Burlamaqui, Conceição Aparecida, Dornelas, Paulo Roberto Carvalho, Almeida, Francisco Vagnaldo Fechine, Jamacaru, Daniel Magalhães Coutinho, Mota, Francisco José Cabral, Mesquita, Lara Albuquerque, de Brito, Lara Burlamaqui, Veras, Lusmar Veras, Rodrigues   +8 more
openaire   +1 more source

Heme iron amplifies azoxymethane initiating effect on rat colon preneoplastic lesions

Redox Experimental Medicine
Objective: Colorectal cancer is a major public health issue for which dietary factors such as red and processed meat consumption seem to play a prominent role. Heme iron, which is present in important concentration in those food products, was reported to
Julia Keller, Pascale Plaisancié, Edwin Fouché, Edwige-Marie Pralet, Nathalie Naud, Florence Blas-Y-Estrada, Claire Maslo, Ingrid Ahn, Sylvie Chevolleau, Maria-Helena Meireles, Cécile Héliès-Toussaint, Sylvia Pietri, Mathieu Cassien, Laure Khoury, Marc Audebert, Fabrice Pierre, Vassilia Theodorou, Maïwenn Olier, Françoise Guéraud   +18 more
doaj   +1 more source

Repercussão hepática da carcinogênese colorretal induzida pelo azoximetano Hepatic repercussions of azoxymethane-induced colorectal carcinogenesis

Revista do Colégio Brasileiro de Cirurgiões, 2013
OBJETIVO: Avaliar as repercussões hepáticas da carcinogênese colônica induzida por diferentes doses e tempos de exposição ao azoximetano em ratos Wistar. MÉTODOS: Quarenta e quatro ratos foram distribuídos em quatro grupos. Os animais tinham oito semanas
Idália Maria Brasil Burlamaqui, Conceição Aparecida Dornelas, Paulo Roberto Carvalho Almeida, Francisco Vagnaldo Fechine Jamacaru, Daniel Magalhães Coutinho Mota, Francisco José Cabral Mesquita, Lara Albuquerque de Brito, Lara Burlamaqui Veras, Lusmar Veras Rodrigues   +8 more
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Wild cherry (Prunus microcarpa) ameliorates azoxymethane-induced aberrant crypt foci in vivo: Depicted molecular mechanisms

ARO-The Scientific Journal of Koya University
Colorectal cancer is the third diagnosed cancer across the globe despite modern therapeutic interventions. Prunus microcarpa has been consumed as a therapeutic tea for several human disorders; therefore, the study investigates the chemoprotective ...
Ahmed A. Abduljabbar, Parween A. Ismail
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Evaluation of Nanocarrier Targeted Drug Delivery of Capecitabine-PAMAM Dendrimer Complex in a Mice Colorectal Cancer Model

Acta Medica Iranica, 2016
Capecitabine, an effective anticancer drug in colorectal cancer chemotherapy, may create adverse side effects on healthy tissues. In the present study, we first induced colon adenocarcinoma with azoxymethane, a carcinogen agent, and then investigated the
Fatemeh Nabavizadeh, Hafseh Fanaei, Alireza Imani, Jalal Vahedian, Fahimeh Asadi Amoli, Jamal Ghorbi, Hamid Sohanaki, Seyed Mehdi Mohammadi, Ravieh Golchoobian   +8 more
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Morphometric investigation of the effects of Azoxymethane, Diallyl disulfide and corn oil use on humerus and femur development in rats

Revista Científica
The study aimed to examine the effects of Azoxymethane (AOM), Diallyl Disulfide (DADS), and corn oil on the humerus and femur in rats. In the study, 40 male Wistar Albino rats, 12 weeks old, were used. The animals were divided into four different groups
Sedat Aydoğdu
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Mangiferin (mango) attenuates AOM-induced colorectal cancer in rat’s colon by augmentation of apoptotic proteins and antioxidant mechanisms

Scientific Reports
Mangiferin (MF) is a natural C-glucosylxantone compound that has many substantial curative potentials against numerous illnesses including cancers.
Khaled Abdul-Aziz Ahmed, Ahmed A. J. Jabbar, Mahmood Ameen Abdulla, Zaenah Zuhair Alamri, Nur Ain Salehen, Ibrahim Abdel Aziz Ibrahim, Ghassan Almaimani, Ghazi A. Bamagous, Riyad A. Almaimani, Hussain A. Almasmoum, Mazen M. Ghaith, Wesam F. Farrash   +11 more
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Effect of Garambullo (<i>Myrtillocactus geometrizans</i>) Consumption on the Intestinal Microbiota Profile in an Early-Phase Rat Model of Colon Cancer. [PDF]

Int J Mol Sci
Sánchez-Recillas E, Almanza-Aguilera E, Bars-Cortina D, Zamora-Ros R, Godínez-Santillán RI, Sánchez-Tusié AA, Vergara-Castañeda HA.   +6 more
europepmc   +1 more source