Study of superoxide dismutase's expression in the colon produced by azoxymethane and inositol hexaphosfate's paper, in mice Estudo da expressão de superóxido dismutase no cólon produzida por azoximetano e o papel do inositol hexafosfato, em ratos
PURPOSE: To investigate the expression of superoxide dismutase (SOD), with use of antioxidant inositol hexaphosfate, in the presence of the carcinogen azoxymethane, in FCA of colon rats.
Eva Glória Abrão Siufi do Amaral +3 more
doaj +1 more source
Endogenous N-nitroso compounds, and their precursors, present in bacon, do not initiate or promote aberrant crypt foci in the colon of rats [PDF]
Processed meat intake is associated with increased risk of colorectal cancer. This association may be explained by the endogenous formation of N-nitroso compounds (NOC).
Corpet, Denis E. +4 more
core +1 more source
Processed Meat and Colorectal Cancer: A Review of Epidemiologic and Experimental Evidence [PDF]
Processed meat intake may be involved in the etiology of colorectal cancer, a major cause of death in affluent countries. The epidemiologic studies published to date conclude that the excess risk in the highest category of processed meat-eaters is ...
Corpet, Denis E. +2 more
core +4 more sources
The review critically evaluated and compared the selected superfruit phytochemistry, their bioactive composition and the key health benefits majorly emphasizing the antioxidant potential. It has highlighted the translational challenges in formulating functional foods by addressing the issues related to delivery system, bioavailability mechanism and the
Sharath Kumar Nagaraja +3 more
wiley +1 more source
Comparison of 2 different mouse models of colorectal cancer and their application
Objective To establish and compare the characteristics of mouse models of colorectal cancer (CRC) induced by inflammation and gene mutation. Methods Inflammation-induced colorectal cancer mouse model was established using azoxymethane (AOM) combined with
FENG Jianhua, LIU Xiangjun, HUANG Yujun
doaj +1 more source
Reelin Protects against Colon Pathology via p53 and May Be a Biomarker for Colon Cancer Progression
Previous observations made in human and mouse colons suggest that reelin protects the colon from pathology. In this study, we evaluated reelin expression during the transition from either colitis or precancerous lesions to colon cancer and tried to ...
José M. Serrano-Morales +6 more
doaj +1 more source
Polyethylene glycol, unique among laxatives, suppresses aberrant crypt foci, by elimination of cells. [PDF]
OBJECTIVE: Polyethylene glycol (PEG), an osmotic laxative, is a potent inhibitor of colon cancer in rats. In a search for the underling mechanisms, the hypothesis that fecal bulking and moisture decrease colon carcinogenesis was tested.
Corpet, Denis E. +3 more
core +3 more sources
In vitro and in vivo effects of PTSO in colorectal cancer preclinical models, highlighting antiproliferative, pro‐apoptotic, barrier‐enhancing, antitumor, prebiotic and immunomodulatory properties. Created using BioRender. ABSTRACT Allium‐derived organosulfur compounds offer significant health benefits.
María Jesús Rodríguez‐Sojo +16 more
wiley +1 more source
Latar belakang: Inflamasi adalah salah satu faktor penyebab terjadinya kanker kolorektal. Flavonoid adalah suatu senyawa yang terkandung dalam daun Carica pubescens diyakini memiliki efek antiinflamasi.
Eka Meyliana Sugeng +2 more
doaj +1 more source
Background: Thrombospondin type 1 domain-containing 7A (THSD7A) has emerged as a new potential molecular tool for multiple tumors since that THSD7A was detected to be expressed in various malignant tumor types including colorectal cancer (CRC).
Oktay Halit Aktepe +8 more
doaj +1 more source

