Results 101 to 110 of about 34,903 (209)

Plasmid-mediated novel blaNDM-17 gene encoding a Carbapenemase with enhanced activity in a sequence type 48 Escherichia coli strain [PDF]

, 2017
Carbapenem-resistant Enterobacteriaceae (CRE) have spread worldwide, leaving very few treatment options available. New Delhi metallo-beta-lactamase (NDM) is the main carbapenemase mediating CRE resistance and is of increasing concern.
Li, Jiyun, Liu, Dejun, Liu, Zhihai, Shen, Jianzhong, Shen, Zhangqi, Walsh, Timothy Rutland, Wang, Yang, Yao, Hong, Yin, Wenjuan, Zhang, Rongmin   +9 more
core   +2 more sources

Safety and Tolerability of Inhaled Aztreonam in Children and Adolescents: A Systematic Review and Meta-Analysis

Advances in Respiratory Medicine
Respiratory infections and chronic lung disease are major contributors to morbidity in children. Aztreonam lysine for inhalation (AZLI) delivers high local antibiotic concentrations while limiting systemic exposure; however, its safety in younger ...
Valmir N. Rastely-Junior, Hosanea S. N. Rocha, Mitermayer G. Reis   +2 more
doaj   +1 more source

In vitro Effect of the Combination of Aztreonam and Amoxicillin/Clavulanic Acid Against Carbapenem-Resistant Gram-Negative Organisms Producing Metallo-β-Lactamase

Infection and Drug Resistance, 2021
Qian Xu,1,2,* Ying Fu,3,* Jingshu Ji,3 Xiaoxing Du,1,2 Yunsong Yu1,2 1Department of Infectious Diseases, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, 310016, People’s Republic of China; 2Key ...
Xu Q, Fu Y, Ji J, Du X, Yu Y
doaj  

Detection of extended spectrum B-lactamases in urinary isolates of Klebsiella pneumoniae in relation to Bla SHV, Bla TEM and Bla CTX-M gene carriage [PDF]

, 2011
Background: Resistance to contemporary broad-spectrum β-lactam antibiotics mediated by extended-spectrum β-lactamases (ESBLs) is increasing worldwide.
Eftekhar, F., Golalipoor, M., Mansoursamaei, N., Rastegar, M.   +3 more
core   +1 more source

Potentiation of Antibiotic Activity of Aztreonam against Metallo-β-Lactamase-Producing Multidrug-Resistant Pseudomonas aeruginosa by 3-O-Substituted Difluoroquercetin Derivatives

Pharmaceutics
The combination of aztreonam (ATM) and ceftazidime–avibactam (CAZ-AVI; CZA) has shown therapeutic potential against serine-β-lactamase (SBL)- and metallo-β-lactamase (MBL)-producing Enterobacterales.
Seongyeon Lee, Taegum Lee, Mi Kyoung Kim, Joong Hoon Ahn, Seri Jeong, Ki-Ho Park, Youhoon Chong   +6 more
doaj   +1 more source

A Simple Disk Stacking Plus Micro-Elution Method for Rapid Detection of the Synergistic Effect of Aztreonam and Ceftazidime/Avibactam Against Metallo-β-Lactamase Producing Enterobacterales

Infection and Drug Resistance, 2023
Zhou Liu,1,* Xiubing Hang,1,* Tao Yan,1 Wenwen Chu,1 Zhen Gong,1 Yanyan Liu,2– 4 Yuanyuan Dai,5 Min Yang,6 Jiabin Li,2– 4 Qiang Zhou1 1Department of Laboratory Medicine, The Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui,
Liu Z, Hang X, Yan T, Chu W, Gong Z, Liu Y, Dai Y, Yang M, Li J, Zhou Q   +9 more
doaj  

Imipenem/Relebactam Plus Aztreonam: First Reported Use in MDR Klebsiella pneumoniae Sternal Infection Complicated by Bacteremia

Antibiotics
Background: Carbapenem-resistant Klebsiella pneumoniae (CRKP) poses a significant therapeutic challenge, particularly when multiple resistance mechanisms, such as metallo-β-lactamases (MBLs) and Klebsiella pneumoniae carbapenemase (KPC), coexist.
Luca Pipitò, Raffaella Rubino, Rita Immordino, Eleonora Bono, Teresa Fasciana, Celestino Bonura, Giovanni Maurizio Giammanco, Vincenzo Argano, Antonio Cascio   +8 more
doaj   +1 more source

How predictable is development of resistance after β-lactam therapy in Enterobacter cloacae infection? [PDF]

, 2016
Certain non-fastidious Gram-negative bacilli, notably Enterobacter cloacae, although classified as susceptible by usual in-vitro susceptibility testing, often become resistant in patients treated with newer β-lactam antibiotics.
Michéa-Hamzehpour, M., Pechère, J. C.
core  

Combination Therapy for OXA-48 Carbapenemase-Producing Klebsiella Pneumoniae Bloodstream Infections in Premature Infant: A Case Report and Literature Review

Infection and Drug Resistance
Yiyu Chen,1 Chuxuan Fang,1 Jun Luo,1 Xueling Pan,2 Zongyan Gao,3 Shuangyi Tang,1 Meng Li4– 6 1Department of Pharmacy, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, People’s Republic of China; 2Newborn ICU, Guigang ...
Chen Y, Fang C, Luo J, Pan X, Gao Z, Tang S, Li M   +6 more
doaj  

Activities of aztreonam in combination with several novel β-lactam-β-lactamase inhibitor combinations against carbapenem-resistant Klebsiella pneumoniae strains coproducing KPC and NDM

Frontiers in Microbiology
Isolates coproducing serine/metallo-carbapenems are a serious emerging public health threat, given their rapid dissemination and the limited number of treatment options.
Xinhui Li, Jisheng Zhang, Jianmin Wang, Wenzhang Long, Xushan Liang, Yang Yang, Xue Gong, Jie Li, Longjin Liu, Xiaoli Zhang   +9 more
doaj   +1 more source