Results 91 to 100 of about 25,663 (196)

Aztreonam Acts as a Synergist for Ceftazidime/Avibactam Against Carbapenem-Resistant Enterobacteriaceae (CRE) of Various Carbapenemase Phenotypes in Southwestern China [PDF]

Xuelian Ruan,1,* Zhiyu Gong,1,* Moqiyi Zeng,1 Ziqing Zhong,1 Yongling Chen,1 Fangyi Wei,1 Chong Lei,1 Yuanyuan Zhu,1 Xue Qin,1 Meng Li1,2 1Department of Clinical Laboratory, The First Affiliated Hospital of Guangxi Medical University, Key
Ruan X, Zhu Y, Zeng M, Wei F, Qin X, Chen Y, Gong Z, Zhong Z, Lei C, Li M   +9 more
core  

Safety and Tolerability of Inhaled Aztreonam in Children and Adolescents: A Systematic Review and Meta-Analysis

Advances in Respiratory Medicine
Respiratory infections and chronic lung disease are major contributors to morbidity in children. Aztreonam lysine for inhalation (AZLI) delivers high local antibiotic concentrations while limiting systemic exposure; however, its safety in younger ...
Valmir N. Rastely-Junior, Hosanea S. N. Rocha, Mitermayer G. Reis   +2 more
doaj   +1 more source

Optimizing target inactivation to treat multidrug-resistant Escherichia coli with NDM and PBP3 mutations: “going the extra mile”

Antimicrobial Agents and Chemotherapy
A 65-year-old man without identifiable risk factors for multidrug-resistant pathogens was admitted with peritonitis, isolating NDM-producing Escherichia coli from a rectal swab and intraoperative samples.
Claudia Fabrizio, Felice Valzano, Simone Giuliano, Elisabetta Morelli, Daniela Serio, Giovanni Battista Buccoliero, Maurizio Cervellera, Gianfranco La Bella, Fabio Arena, Andrea M. Hujer, Magdalena A. Taracila, Steven H. Marshall, Robert A. Bonomo, Carlo Tascini   +13 more
doaj   +1 more source

Ceftazidime/avibactam and aztreonam combined with an aminoglycoside combat metallo-β-lactamase-producing Klebsiella pneumoniae

Antimicrobial Agents and Chemotherapy
There is an urgent need for additional therapeutic solutions to treat serious bacterial infections caused by metallo-β-lactamase (MBL)-producing Klebsiella pneumoniae.
Arunkumar Karunanidhi, Nidhi Singh, Jackson V. Watkins, Nicholas M. Smith, Yanan Zang, Xindi Shan, Gilberto Espinoza, Jian Li, Yinzhi Lang, Jürgen B. Bulitta, Zackery P. Bulman   +10 more
doaj   +1 more source

Avaliação do sinergismo entre ceftazidima/avibactam-aztreonam e aztreonam/avibactam frente a Klebsiella pneumoniae utilizando espectrometria de massa maldi-tof

A disseminação de Enterobacterales produtores de carbapenemases, especialmente do tipo NDM, representa um importante desafio terapêutico, devido à elevada resistência aos antimicrobianos β-lactâmicos e à escassez de opções terapêuticas eficazes ...
Santos, Jéssica Nesello dos
core  

Contemporary in vitro synergy rates for aztreonam combined with newer fluoroquinolones and beta-lactams tested against gram-negative bacilli

, 2003
Aztreonam has been commonly used in various combinations to enhance antimicrobial spectrum of co-drugs and produce potential synergistic activity. Although well studied in vitro over 10 years ago, aztreonam combination testing has been poorly documented ...
Sader, H. S., Jones, R. N., Huynh, H. K.
core   +1 more source

Combination of Ceftazidime-Avibactam and Aztreonam Effectively Treated Post-Cardiac Surgery Pneumonia Caused by Hypervirulent KPC- and NDM-Producing Klebsiella pneumoniae: A Case Report

Infection and Drug Resistance
Qimei Wei,1,* Rong Cong,1,* Chang Shen,2 Chen Chen,1 Zheng Cao,1 Chanjun Ren,3 Tingting Liu2 1Department of Clinical Laboratory, Wuhan Asia Heart Hospital, Wuhan, 430022, People’s Republic of China; 2Department of Cardiac Critical Care ...
Wei Q, Cong R, Shen C, Chen C, Cao Z, Ren C, Liu T   +6 more
doaj  

Phenotypic detection of carbapenem-resistant Enterobacterales and carbapenem-resistant Pseudomonas aeruginosa by mCIM and eCIM and their ceftazidime-avibactam with aztreonam synergy profile in a tertiary care hospital in Eastern India

Asian Journal of Medical Sciences
Background: Worldwide, the emergence of carbapenem-resistant enterobacterales (CRE) and carbapenem-resistant Pseudomonas aeruginosa (CRPA) is a global concern to public health as they are responsible for several serious infections that lead to elevated ...
Payel Chanda , Sharmila Gupta , Saswati Chattopadhyay , Soma Bose   +3 more
doaj   +1 more source

Contributions and Evolutionary Potential of ampC Mutations to confer Aztreonam Resistance in Pseudomonas aeruginosa

, 2019
Thesis (Master's)--University of Washington, 2019Aztreonam is a synthetic monobactam antibiotic that is increasingly used for chronic suppressive therapy in Cystic Fibrosis (CF) patients with Pseudomonas aeruginosa airway infection. P.
Lee, Duan-kun
core  

Comparative in vitro activity of aztreonam–avibactam and aztreonam plus ceftazidime–avibactam against Stenotrophomonas maltophilia complex

Members of the Stenotrophomonas maltophilia complex are intrinsically multidrug-resistant pathogens that disproportionately affect critically ill patients.
Gray, Rachel, Tamma, Pranita A., Do, Alex, Coyne, Ashlan J. Kunz, Gonnabathula, Pavani, May, Elizabeth S.   +5 more
core   +1 more source