Results 81 to 90 of about 25,663 (196)
ObjectiveThis study aims to investigate the synergistic effects and biofilm inhibition mechanisms of ceftazidime-avibactam (CZA) combined with aztreonam (ATM) against carbapenem-resistant Klebsiella pneumonia (CRKP) commonly found in the local clinical ...
Guangfen Wang +8 more
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Aztreonam therapy of gram-negative septicemia
Aztreonam is a new monobactam antibiotic with high in vitro activity restricted to aerobic gram-negative bacteria. Eighteen patients were treated in an open clinical study with aztreonam 3 to 6 gm intravenously/day.
Van de Perre, Philippe +2 more
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Análise químico-farmacêutica de preparações injetáveis de Aztreonam
Aztreonam is a β-lactam antibiotic, synthetic, monocyclic with bactericidal activity against Gram-negative bacteria. It was discovered in 1978, and it was the first antibiotic of the monobactam family to be therapeutically approved. It can be used in the
Figueiredo, Andressa Leme de [UNESP]
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The stability of the monocyclic beta-lactam antibiotic aztreonam in portable pump reservoirs was studied during storage at temperatures of -20 degrees C and +5 degrees C and during drug delivery at 37 degrees C.
Touw, D J; id_orcid +4 more
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The enzymes responsible for the synthesis of the peptidoglycan (PG) layer constitute a fundamental target for a large group of antibiotics. The family of β-lactam antibiotics inhibits the DD-transpeptidase (TPase) activity of the penicillin binding ...
Alejandro Montón Silva +6 more
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Aztreonam is a monocyclic synthetic antimicrobial with bactericidal activity against Gram-negative bacteria, the first agent from the monobactam family to be therapeutically approved.
Andressa Leme Figueiredo +2 more
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Evolved metabolic-level adaptations in the aztreonam-resistant strain.
(A) Metabolic flux changes relative to the reference condition S0 (D-3rsw, no aztreonam). (B) Venn diagram showing the overlap between reactions whose flux levels significantly altered by aztreonam alone, mutations alone, and their combination. Among all
Wook Kim (220700) +9 more
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Is Inappropriate Documentation of Penicillin Allergy Related to Overuse of Aztreonam? [PDF]
Background: Penicillin allergy is one of the most common drug allergies, with a 10% prevalence in the United States. Only 10% of patients who self-report a penicillin allergy will react if given penicillin, and only 1% will experience an Immunoglobulin E
Adefisoye, James +3 more
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Aztreonam compared with gentamicin for treatment of serious urinary tract infections.
52 patients with serious urinary tract infections were randomised to receive either aztreonam (35) or gentamicin (17). In the aztreonam group 23 patients had unqualified cures, 6 cures with relapse, and 6 cures with reinfection; the comparable numbers in
Moyer, James E, MD +4 more
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Therapeutic Options for Metallo-β-Lactamase-Producing Enterobacterales [Corrigendum]
Tan X, Kim HS, Baugh K, et al. Infect Drug Resist.2021;14:125–142. Page 134, left column, second paragraph, fourth sentence from the bottom, the text “Generally, all four tetracyclines have higher tissue concentrations than ...
Tan X +8 more
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