Results 81 to 90 of about 23,919 (200)

Contemporary in vitro synergy rates for aztreonam combined with newer fluoroquinolones and beta-lactams tested against gram-negative bacilli [PDF]

, 2003
Aztreonam has been commonly used in various combinations to enhance antimicrobial spectrum of co-drugs and produce potential synergistic activity. Although well studied in vitro over 10 years ago, aztreonam combination testing has been poorly documented ...
Sader, H. S., Jones, R. N., Huynh, H. K.
core   +1 more source

Potentiation of Antibiotic Activity of Aztreonam against Metallo-β-Lactamase-Producing Multidrug-Resistant Pseudomonas aeruginosa by 3-O-Substituted Difluoroquercetin Derivatives

Pharmaceutics
The combination of aztreonam (ATM) and ceftazidime–avibactam (CAZ-AVI; CZA) has shown therapeutic potential against serine-β-lactamase (SBL)- and metallo-β-lactamase (MBL)-producing Enterobacterales.
Seongyeon Lee, Taegum Lee, Mi Kyoung Kim, Joong Hoon Ahn, Seri Jeong, Ki-Ho Park, Youhoon Chong   +6 more
doaj   +1 more source

Tolerability of Aztreonam in Patients with Cell-Mediated Allergy to β-Lactams [PDF]

, 2010
<i>Background:</i> Cross-reactivity between aztreonam and β-lactams is poor, but tolerability of aztreonam has been assessed in a few groups of patients suffering from IgE-mediated allergy to β-lactams. The aim of this study was to assess the
G. Patriarca, V. Sabato, C. Lombardo, D. Schiavino, V. Pecora, A. Rizzi, A. Buonomo, A. Colagiovanni, E. Nucera, L. Pascolini, A. Aruanno, T. De Pasquale   +11 more
core   +1 more source

Imipenem/Relebactam Plus Aztreonam: First Reported Use in MDR Klebsiella pneumoniae Sternal Infection Complicated by Bacteremia

Antibiotics
Background: Carbapenem-resistant Klebsiella pneumoniae (CRKP) poses a significant therapeutic challenge, particularly when multiple resistance mechanisms, such as metallo-β-lactamases (MBLs) and Klebsiella pneumoniae carbapenemase (KPC), coexist.
Luca Pipitò, Raffaella Rubino, Rita Immordino, Eleonora Bono, Teresa Fasciana, Celestino Bonura, Giovanni Maurizio Giammanco, Vincenzo Argano, Antonio Cascio   +8 more
doaj   +1 more source

A Simple Disk Stacking Plus Micro-Elution Method for Rapid Detection of the Synergistic Effect of Aztreonam and Ceftazidime/Avibactam Against Metallo-β-Lactamase Producing Enterobacterales

Infection and Drug Resistance, 2023
Zhou Liu,1,* Xiubing Hang,1,* Tao Yan,1 Wenwen Chu,1 Zhen Gong,1 Yanyan Liu,2– 4 Yuanyuan Dai,5 Min Yang,6 Jiabin Li,2– 4 Qiang Zhou1 1Department of Laboratory Medicine, The Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui,
Liu Z, Hang X, Yan T, Chu W, Gong Z, Liu Y, Dai Y, Yang M, Li J, Zhou Q   +9 more
doaj  

Treatment of gram-negative peritonitis with aztreonam in patients undergoing continuous ambulatory peritoneal dialysis [PDF]

, 1991
In a multicenter open study, intraperitoneal aztreonam was used together with vancomycin, cloxacillin, or flucloxacillin for initial empiric treatment of peritonitis associated with continuous ambulatory peritoneal dialysis (CAPD).
Sabine Lauwers, Mario Schurgers, Glupczynski, Youri, Verbeelen, Dirk, Verschraegen, Gerda, Schurgers, Mario, Dirk Verbeelen, Max Dratwa, Boelaert, Johan, Dirk Matthys, Lauwers, Sabine, Matthys, Dirk, Norbert Lameire, Verbeelen, Dierik, Herman Van Landuyt, Youri Glupczynski, Gerda Verschraegen, Boelaert, Johan R., Schurgers, Mario L C M., Dratwa, Max, Van Landuyt, Herman, Mario Vaneechoutte, Vaneechoutte, Mario, Lameire, Norbert, Matthys, D., Johan Boelaert   +25 more
core   +2 more sources

Repurposing an Old Drug: Aztreonam as a New Treatment Strategy for Gonorrhoea [PDF]

, 2017
International audienceObjectives: To determine whether aztreonam is still an effective drug for the treatment of gonorrhoea.Methods: Observational study of patients with gonorrhoea diagnosed by urine multiplex PCR, with a past medical history of allergy ...
Makhloufi, Sabrina, Dinh, Aurélien, Calin, Ruxandra, Davido, Benjamin, Senard, Olivia, Salomon, Jérôme   +5 more
core   +1 more source

Improving Aztreonam Stewardship and Cost Through a Penicillin Allergy Testing Clinical Guideline [PDF]

, 2018
Background Patients reporting penicillin allergy often receive unnecessary and costly broad-spectrum alternatives such as aztreonam with negative consequences. Penicillin allergy testing improves antimicrobial therapy but is not broadly
David A Khan, Justin R Chen, Scott A Tarver, Kristin S Alvarez, Wenjing Wei   +4 more
core   +1 more source

The Fluorescent D-Amino Acid NADA as a Tool to Study the Conditional Activity of Transpeptidases in Escherichia coli

Frontiers in Microbiology, 2018
The enzymes responsible for the synthesis of the peptidoglycan (PG) layer constitute a fundamental target for a large group of antibiotics. The family of β-lactam antibiotics inhibits the DD-transpeptidase (TPase) activity of the penicillin binding ...
Alejandro Montón Silva, Christian Otten, Jacob Biboy, Eefjan Breukink, Michael VanNieuwenhze, Waldemar Vollmer, Tanneke den Blaauwen   +6 more
doaj   +1 more source

Efficacy of aztreonam/avibactam against Stenotrophomonas maltophilia alone and in combination with tigecycline [PDF]

Background and Aims: Stenotrophomonas maltophilia is a multidrug-resistant opportunistic pathogen that threatens human and public health because of its widespread intrinsic and acquired antibiotic resistance.
Altunboga, Gulbeyaz, OYARDI, ÖZLEM, OLCAY, Fatıma Nur, ERTURAN, Zayre   +3 more
core   +1 more source