Results 181 to 190 of about 16,488,690 (299)

Utility of mimicking B cell epitopes between Mycobacterium leprae and host as prognostic biomarkers in type 1 reaction in leprosy. [PDF]

Sci Rep
Pathak VK, Singh I, Sharma R, Turankar RP, Sengupta U.   +4 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Fine-Mapping and Protective Analysis of Immunodominant Linear B-Cell Epitopes of FimA Antigen of Klebsiella Pneumoniae. [PDF]

Vaccines (Basel)
Yan P, Chen L, Ming G, Chen Z, Gou Q, Yuan Y, Jing H, Luo P, Zhang J, Zhao Z.   +9 more
europepmc   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

<i>In silico</i> discovery and serological validation of <i>Trypanosoma cruzi</i>-specific B-cell epitopes for high-precision Chagas disease diagnosis. [PDF]

Front Microbiol
Candia-Puma MA, Goyzueta-Mamani LD, Barazorda-Ccahuana HL, Câmara RSB, Pereira IAG, Silva AL, Rodrigues MM, Assis BPN, Chaves AT, Corrêa LAVA, Rocha MODC, Gonçalves DU, Gonçalves AAM, de Moura AB, Galdino AS, Machado-de-Avila RA, Giunchetti RC, Coelho EAF, Chávez-Fumagalli MA.   +18 more
europepmc   +1 more source

BCEDB: a linear B-cell epitopes database for SARS-CoV-2. [PDF]

Database (Oxford), 2023
Tai C, Li H, Zhang J.
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Predicted T-Cell and B-Cell Epitopes of NIS: Where Do Sjögren's Syndrome and Hashimoto's Thyroiditis Converge? [PDF]

Int J Mol Sci
Talotta R, Cammaroto G, Ruggeri RM, Postorino E, Cannavò S, Aragona P.   +5 more
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

In silico-predicted B-cell epitopes for bovine brucellosis serodiagnosis: Preliminary analytical evaluation of synthetic peptide- and multi-epitope protein-based indirect ELISAs. [PDF]

PLoS One
de Souza LDR, Souza MFS, Lima PA, Cirilo TM, Ribeiro LN, Carvalho SAP, de Sá Guimarães A, de Souza PG, Soares Filho PM, Reis Cunha JL, Bueno LL, Alves da Paixão T, Fujiwara RT, Santos RL.   +13 more
europepmc   +1 more source