Results 1 to 10 of about 12,449,745 (282)

Escherichia coli shares T- and B-lymphocyte epitopes with Schistosoma mansoni

Journal of Infection in Developing Countries, 2009
Background: In this study, we tested the cross-reaction between crude Escherichia coli antigen (ECA) and 3 crude Schistosoma mansoni antigens. Methodology: The schistosomal antigens used were cercarial antigen preparation (CAP), soluble worm antigen ...
Mahmoud Mohamed Bahgat, Hanaa Mohamed Gaber, Amany Sayed Maghraby   +2 more
doaj   +4 more sources

Different dose-based multi HN & F epitope mRNA vaccine against Newcastle disease [PDF]

Open Veterinary Journal
Background: Newcastle disease virus (NDV) is considered a major player in the ongoing challenges in the poultry farming system due to its virulence, which affects productivity.
Asma Abdlhusen Shrshoh, Nafea Sabih Jasim   +1 more
doaj   +2 more sources

Bioinformatics-driven design and protective efficacy assessment of a multi-epitope vaccine for Toxoplasma gondii [PDF]

Frontiers in Immunology
IntroductionToxoplasma gondii can cause toxoplasmosis. It is an important type of pathogen within the broad category of emerging and re-emerging zoonoses.
Wenyong Feng, Wenyong Feng, Lu Sun, Chenglong Yang, Chenglong Yang, Jie Cao, Yongzhi Zhou, Jinlin Zhou, Longzheng Yu, Houshuang Zhang   +9 more
doaj   +2 more sources

Immunoinformatics Design of a Broad-Spectrum Multi-Epitope Vaccine Targeting HA2 and M1 of H9N2 AIV [PDF]

Microorganisms
H9N2 avian influenza virus (AIV) continues to mutate, leading to immunosuppression and secondary infections in poultry. Traditional inactivated vaccines mainly induce humoral immunity and have limited cross-protection efficacy against various subtypes of
Jiashuang Ji, Yating Lin, Zijian Zhu, Kaixuan Yue, Yunhang Zhang, Wuchao Zhang, Baishi Lei, Wanzhe Yuan, Liwei Li, Kuan Zhao   +9 more
doaj   +2 more sources

Immunoinformatic Design and Evaluation of a Multi-Epitope mRNA Vaccine RP14914P Targeting Latent Tuberculosis Infection [PDF]

Pathogens
Background: Latent tuberculosis infection (LTBI) is the principal reservoir for active tuberculosis, with >85% of cases attributable to reactivation. Bacillus Calmette-Guérin fails to block this transition, leaving a critical gap in prevention.
Yuan Tian, Mingming Zhang, Syed Luqman Ali, Aigul Abduldayeva, Shuang Zhou, Yajing An, Yufeng Li, Ruizi Ni, Lingxia Zhang, Yanhua Liu, Weiguo Sun, Wenping Gong   +11 more
doaj   +2 more sources

Phylogenetic and Immune Epitope Analysis of Hepatitis B Surface Antigen in Chronic Carriers from Tabriz, Northwest of Iran [PDF]

ImmunoAnalysis, 2022
Background: The purpose of this investigation was to specify the genotypes and subtypes of hepatitis B virus (HBV) by phylogenetic analysis and to investigate the mutations in the S gene region in chronic patients with hepatitis B surface antigen (HBsAg)-
Fatemeh Ebrahimi, Mahin Ahangar Oskoee, Hossein Bannazadeh Baghi, Javid Sadeghi, Mohammad Ahangarzadeh Rezaei, Omid Gholizadeh, Nader Mohammadzadeh, Ahmad Dashti, Vahdat Poortahmasebi   +8 more
doaj   +1 more source

Design of a Recombinant Multivalent Epitope Vaccine Based on SARS-CoV-2 and Its Variants in Immunoinformatics Approaches

Frontiers in Immunology, 2022
The development of an effective multivalent vaccine against SARS-CoV-2 variants is an important means to improve the global public health situation caused by COVID-19. In this study, we identified the antigen epitopes of the main global epidemic SARS-CoV-
Mingkai Yu, Mingkai Yu, Yuejie Zhu, Yujiao Li, Zhiqiang Chen, Zhiqiang Chen, Zhiwei Li, Jing Wang, Zheng Li, Fengbo Zhang, Fengbo Zhang, Jianbing Ding, Jianbing Ding   +12 more
doaj   +1 more source

Designing a multi-epitope vaccine against Peptostreptococcus anaerobius based on an immunoinformatics approach

Synthetic and Systems Biotechnology, 2023
Peptostreptococcus anaerobius is an anaerobic bacterium, which has been found selectively en-riched in the fecal and mucosal microbiota of colorectal cancer (CRC) patients. Emerging evidence suggest P.
Yudan Mao, Xianzun Xiao, Jie Zhang, Xiangyu Mou, Wenjing Zhao   +4 more
doaj   +1 more source

Exploring the structural basis to develop efficient multi-epitope vaccines displaying interaction with HLA and TAP and TLR3 molecules to prevent NIPAH infection, a global threat to human health.

PLoS ONE, 2023
Nipah virus (NiV) is an emerging zoonotic virus that caused several serious outbreaks in the south asian region with high mortality rates ranging from 40 to 90% since 2001. NiV infection causes lethal encephalitis and respiratory disease with the symptom
Sukrit Srivastava, Sonia Verma, Mohit Kamthania, Ajay Kumar Saxena, Kailash C Pandey, Veena Pande, Michael Kolbe   +6 more
doaj   +3 more sources

Design of a multi-epitope vaccine candidate against Brucella melitensis

Scientific Reports, 2022
Brucella is a typical facultative intracellular bacterium that can cause zoonotic infections. For Brucella, it is difficult to eliminate with current medical treatment.
Min Li, Yuejie Zhu, Ce Niu, Xinru Xie, Gulishati Haimiti, Wenhong Guo, Mingkai Yu, Zhiqiang Chen, Jianbing Ding, Fengbo Zhang   +9 more
doaj   +1 more source