Results 251 to 260 of about 16,488,690 (299)

High heterogeneity of cross-reactive immunoglobulins in multiple sclerosis presumes combining of B-cell epitopes for diagnostics: a case-control study. [PDF]

open access: yesFront Immunol
Ovchinnikova LA   +11 more
europepmc   +1 more source

Identification of two novel B cell epitopes on E184L protein of African swine fever virus using monoclonal antibodies. [PDF]

open access: yesVirus Res
Tesfagaber W   +12 more
europepmc   +1 more source

What Is a B-Cell Epitope?

Research in Microbiology, 2009
The antigenicity of proteins resides in different types of antigenic determinants known as continuous and discontinuous epitopes, cryptotopes, neotopes, and mimotopes. All epitopes have fuzzy boundaries and can be identified only by their ability to bind to certain antibodies.
openaire   +4 more sources

Prediction of Linear B-cell Epitopes

Molecular Biology, 2009
The prediction of B-cell epitopes is desirable for designing peptide-based vaccines, or generating antibodies especially if the purified protein is difficult to obtain and immunization has to be performed with protein-derived synthetic peptides. A number of freely available tools predict epitopes from protein sequence or structural information.
Ya. I. Davydov, A. G. Tonevitsky
openaire   +3 more sources

B‐cell epitope spreading in autoimmunity

Immunological Reviews, 1998
Summary: How the immune response matures from recognizing a single or a few structures of the antigen to many is an obviously important process. Models of B‐cell epitope spreading have been developed in a variety of systems. For example, immunization of animals with PPPGMRPP, one of the earliest B‐cell epitopes in the anti‐Sm response found in human ...
J A, James, J B, Harley
openaire   +2 more sources

Databases for B-Cell Epitopes

2014
Identification and characterization of B-cell epitopes in target antigens is one of the key steps in epitope-driven vaccine design, immunodiagnostic tests, and antibody production. For localizing epitopes by experimental methods is time consuming and cost expensive, researchers have been developing in silico or computational models for the prediction ...
Juan, Liu, Wen, Zhang
openaire   +2 more sources

Prediction of Conformational B-Cell Epitopes

2014
Conformational B-cell epitopes play an important role in the epitope-based vaccine design. The increase of available data promotes the development of computational methods. Compared with the wet experiments, the computational methods are faster and more economic.
Wen, Zhang   +3 more
openaire   +2 more sources

Prediction Methods for B-cell Epitopes

2007
In this chapter, two prediction servers of linear B-cell epiotpes have been described; (i) BcePred, based on physico-chemical properties that include hydrophilicity, flexibility/mobility, accessibility, polarity, exposed surface, turns, and antigenicity and ii) ABCpred, based on recurrent neural network.
Sudipto, Saha, Gajendra P S, Raghava
openaire   +2 more sources

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