Results 31 to 40 of about 16,488,690 (299)

ZIKV B-cell epitopes for immunodiagnostic tests

open access: yesJournal of Immunological Methods, 2022
The use of serological tests is valuable to diagnose Zika virus (ZIKV) infection and carry out epidemiological surveillance. However, ZIKV serological tests may result in false positives due to cross-reactivity between antibodies against other Flavivirus, especially dengue virus that worldwide disseminated.
Kubiszeski, Janaina Rigotti   +10 more
openaire   +4 more sources

Predicting linear B‐cell epitopes using string kernels [PDF]

open access: yes, 2008
The identification and characterization of B-cell epitopes play an important role in vaccine design, immunodiagnostic tests, and antibody production. Therefore, computational tools for reliably predicting linear B-cell epitopes are highly desirable.
Vasant Honavar   +5 more
core   +1 more source

Identification of B cell epitopes of alcohol dehydrogenase allergen of Curvularia lunata. [PDF]

open access: yesPLoS ONE, 2011
BACKGROUND/OBJECTIVE: Epitope identification assists in developing molecules for clinical applications and is useful in defining molecular features of allergens for understanding structure/function relationship.
Smitha Nair   +3 more
doaj   +1 more source

An analysis of B-cell epitope discontinuity

open access: yesMolecular Immunology, 2012
Although it is widely acknowledged that most B-cell epitopes are discontinuous, the degree of discontinuity is poorly understood. For example, given that an antigen having a single epitope that has been chopped into peptides of a specific length, what is the likelihood that one of the peptides will span all the residues belonging to that epitope?
Sivalingam, GN, Shepherd, AJ
openaire   +3 more sources

Overlapping CTL, HTL and B cell epitopes.

open access: yes, 2023
Multiple sequence alignment performed by Clustal Omega at EBI to identify the consensus overlapping regions of CTL (red), HTL (blue) and B cell epitopes (green) amongst shortlisted epitopes. Epitopes with overlapping region amongst all the three types of
Sonia Verma (3630100)   +6 more
core   +1 more source

Computational Prediction of B-cell Epitopes of Mycobacterium tuberculosis-Implications in Vaccine Design

open access: yesMediterranean Journal of Infection, Microbes and Antimicrobials, 2021
Introduction: Tuberculosis (TB) is a communicable disease caused by Mycobacterium tuberculosis. Bacillus Calmette-Guérin is the only vaccine available for TB.
Esakkimuthu THANGAMARIAPPAN   +2 more
doaj   +1 more source

Human T cell responses to peptides of the Mycobacterium leprae 45-kD serine-rich antigen. [PDF]

open access: yes, 2002
In order to identify T cell epitopes within the Mycobacterium leprae 45-kD serine-rich antigen, we analysed responses to overlapping 17-mer peptides encompassing the whole antigen in non-exposed UK controls, Pakistani leprosy patients and tuberculosis ...
Zafar, S   +9 more
core   +1 more source

Prediction of T and B Cell Epitopes in the Proteome of SARS-CoV-2 for Potential Use in Diagnostics and Vaccine Design [PDF]

open access: yes, 2020
The world is currently battling the Covid-19 pandemic for which there is no therapy available. Prophylactic measures like vaccines can effectively thwart the disease burden.
Parvez, Slathia   +3 more
core   +1 more source

In silico prediction of T- and B-cell epitopes in PmpD: First step towards to the design of a Chlamydia trachomatis vaccine

open access: yesBiomedical Journal, 2018
Background: Chlamydia trachomatis is the most common sexually transmitted bacterial infection globally. Currently, there are no vaccines available despite the efforts made to develop a protective one.
Romina Cecilia Russi   +3 more
doaj   +1 more source

Human monoclonal islet specific autoantibodies share features of islet cell and 64 kDa antibodies [PDF]

open access: yes, 1993
The first human monoclonal islet cell antibodies of the IgG class (MICA 1-6) obtained from an individual with Type 1 (insulin-dependent) diabetes mellitus were cytoplasmic islet cell antibodies selected by the indirect immunofluorescence test on pancreas
Brandt, M.   +7 more
core   +1 more source

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