Results 11 to 20 of about 12,336,620 (246)

Expressió de ZAP-70 en linfòcits B normals i síndromes limfoproliferatives B [PDF]

open access: yes, 2006
[cat] La Leucèmia Limfàtica Crònica (LLC), la més freqüent de les leucèmies en el món occidental, és una malaltia produïda per la proliferació i cúmul de limfòcits B madurs, actualment incurable.
Crespo Maull, Marta
core   +6 more sources

Chronic lymphocytic leukaemia: Up-dated recommendations on diagnosis and treatment [PDF]

open access: yes, 2004
Diagnosis and treatment of chronic lymphatic leukaemia (CLL) are currently undergoing great change. New knowledge of prognosis factors and the numerous new therapeutic procedures now available, such as purine analogues, high-dose treatment and monoclonal
Hallek, M., Emmerich, B., Bergmann, M.
core   +1 more source

Chronic Lymphocytic Leukemia B-Cell Normal Cellular Counterpart: Clues From a Functional Perspective

open access: yesFrontiers in Immunology, 2018
Chronic lymphocytic leukemia (CLL) is characterized by the clonal expansion of small mature-looking CD19+ CD23+ CD5+ B-cells that accumulate in the blood, bone marrow, and lymphoid organs.
Walaa Darwiche   +8 more
doaj   +1 more source

Chlorambucil effect on B lymphocites in the peripheral blood of patients with chronic lymphocytic leukemia: Cell ultrastructure investigation [PDF]

open access: yesVojnosanitetski Pregled, 2003
B type Chronic Lymphocytic Leukemia (B-CLL) is a malignant disease characterized by the progressive accumulation of morphologically mature, but immunologically dysphunctional CD 5+ lymphocytes in the blood, bone marrow and lymphatic organs in the early ...
Brajušković Goran R.   +2 more
doaj   +1 more source

BTLA Expression in CLL: Epigenetic Regulation and Impact on CLL B Cell Proliferation and Ability to IL-4 Production

open access: yesCells, 2021
In our previous study, while chronic lymphocytic leukemia (CLL) cases showed higher levels of B and T lymphocyte attenuator (BTLA) mRNA compared to controls, lower BTLA protein expression was observed in cases compared to controls.
Lidia Karabon   +9 more
doaj   +1 more source

Functional interaction between CD180 Toll-like receptor (TLR) and B cell receptor (BCR) in the biology of Chronic Lymphocytic Leukaemia (CLL) [PDF]

open access: yes, 2017
Chronic Lymphocytic Leukaemia (CLL) is the most common leukaemia in the western world and remains incurable. It is driven by as yet unknown (auto)antigens via the B cell receptor (BCR) and growth, survival and expansion signals it receives from the ...
Rajakaruna, A.
core   +1 more source

Enhanced CDC of B cell chronic lymphocytic leukemia cells mediated by rituximab combined with a novel anti-complement factor H antibody. [PDF]

open access: yesPLoS ONE, 2017
Rituximab therapy for B cell chronic lymphocytic leukemia (B-CLL) has met with mixed success. Among several factors to which resistance can be attributed is failure to activate complement dependent cytotoxicity (CDC) due to protective complement ...
Mark T Winkler   +7 more
doaj   +1 more source

Dasatinib inhibits CXCR4 signaling in chronic lymphocytic leukaemia cells and impairs migration towards CXCL12 [PDF]

open access: yes, 2012
Chemokines and their ligands play a critical role in enabling chronic lymphocytic leukaemia (CLL) cells access to protective microenvironmental niches within tissues, ultimately resulting in chemoresistance and relapse: disruption of these signaling ...
McCaig, Alison M.   +14 more
core   +1 more source

Generation of Functional CLL-Specific Cord Blood CTL Using CD40-Ligated CLL APC [PDF]

open access: yes, 2012
PMCID: PMC3526610This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
John G. Gribben   +49 more
core   +2 more sources

Burnout en el personal del área de salud y estrategias de afrontamiento

open access: yesCorreo Científico Médico, 2020
El burnout es un síndrome psicológico caracterizado por la presencia de manifestaciones sugestivas de agotamiento emocional, despersonalización y baja realización personal.
Diana Sofia Serna Corredor   +1 more
doaj  

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