Results 21 to 30 of about 12,336,620 (246)

Comparative Assessment of Machine Learning and Neural Network Models for Asbestos–Cement Detection in VNIR Images

Digital
Hyperspectral imaging is a well-established remote sensing technique for material detection and classification, relying on hundreds of reflectance bands to exploit the spectral signatures of surface materials.
Gabriel Elías Chanchí-Golondrino, Isaac Esteban Camargo Freile, Julio Eduardo Mejía Manzano, Manuel Saba, Manuel Alejando Ospina-Alarcón   +4 more
doaj   +1 more source

Genetikai eltérések vizsgálata Multiplex Ligáció-függő Próba Amplifikáció (MLPA) módszerrel krónikus limocitás leukémiás (CLL) betegekben

, 2023
A krónikus limfoid leukémia (CLL) a felnőttkori leukémia leggyakoribb formája. Ez a betegség genetikailag rendkívül heterogén, a CLL-ben szenvedő betegek körülbelül 85%-a olyan kromoszóma-rendellenességeket hordoz, amelyek fontos prognosztikai ...
B. Balog, Boglárka
core  

Prognostic factors for survival in patiens with chronic lymphocytic leukemia [PDF]

, 2012
The purpose of this study is to analyse the quality of the prognostic factors to prognose the survival time and progression for patients with chronic lymphocytic leukemia (CLL) in early stage.
Wijaya, Ferry
core   +1 more source

The Elevation and Impact of Peripheral Bile Acids in Chronic Lymphocytic Leukemia

Biomedicines
Background: Chronic lymphocytic leukemia (CLL) is the most prevalent adult leukemia in the Western world. Targeted therapies have made CLL manageable for many patients, but the ongoing threat of disease relapse or transformation beckons a deeper ...
Audrey L. Smith, Abigail Ridout, Sydney A. Skupa, Rolando Martinez-Rico, Erin M. Drengler, Eslam Mohamed, Christopher R. D’Angelo, Dalia El-Gamal   +7 more
doaj   +1 more source

Survival mechanisms in B lymphoid malignancies and associated therapies [PDF]

, 2011
PhDThe apoptotic pathway plays critical roles in regulating lymphocyte survival throughout B cell development, maturation and differentiation. The whole process involves clonal expansion. In the normal B lymphocyte population the majority of cells and
Su, Bo
core   +4 more sources

Increased serum level of alpha-2 macroglobulin and its production by B-lymphocytes in chronic lymphocytic leukemia

Frontiers in Immunology, 2022
Chronic lymphocytic leukemia (CLL), the most common adult’s leukemia in the western world, is caused in 95% of the cases by uncontrolled proliferation of monoclonal B-lymphocytes.
Regina Michelis, Lama Milhem, Lama Milhem, Evleen Galouk, Evleen Galouk, Galia Stemer, Galia Stemer, Ariel Aviv, Tamar Tadmor, Tamar Tadmor, Mona Shehadeh, Lev Shvidel, Lev Shvidel, Masad Barhoum, Andrei Braester, Andrei Braester   +15 more
doaj   +1 more source

Biophysical Characterization and Expression Analysis of Kv1.3 Potassium Channel in Primary Human Leukemic B Cells

Cellular Physiology and Biochemistry, 2015
Background/Aims: Pharmacological inhibition of the potassium channel Kv1.3 has been shown to selectively kill B cells from patients with chronic lymphocytic leukemia (B-CLL).
Ildiko Szabo, Livio Trentin, Valentina Trimarco, Gianpietro Semenzato, Luigi Leanza   +4 more
doaj   +1 more source

Mass cytometry analysis reveals attrition of naïve and anergized self-reactive non-malignant B cells in chronic lymphocytic leukemia patients

Frontiers in Oncology, 2022
Chronic Lymphocytic Leukemia (CLL) is characterized by the progressive accumulation of monoclonal mature B lymphocytes. Autoimmune complications are common in CLL occurring in up to a quarter of all patients during the course of the illness.
Thibault Andrieu, Paul Mondière, Pierre-Emmanuel Jouve, Sébastien Dussurgey, Victor Malassigné, Hugo Servanton, Lucille Baseggio, Frédéric Davi, Anne-Sophie Michallet, Thierry Defrance   +9 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

FEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar, Sally Agersborg, Ahmed Charifa, Pooja Phull, Noa Biran, David Vesole, Harsh Parmar, Andrew Pecora, Andrew Ip, Andre Goy, David Siegel, Maher Albitar   +11 more
wiley   +1 more source