Results 301 to 310 of about 773,820 (334)
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Immunology Today, 1981
A review focussing on the lessons learned from polyclonal activation of B cells.
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A review focussing on the lessons learned from polyclonal activation of B cells.
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New England Journal of Medicine, 1973
The division of the lymphoid system into two major functionally distinct kinds of cells has increased immensely understanding not only of normal immunity but also of neoplasia affecting these cells. It is now abundantly clear that certain lymphocytes are conditioned by the thymus (hence their designation as T-cells) and acquire the ability to mediate ...
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The division of the lymphoid system into two major functionally distinct kinds of cells has increased immensely understanding not only of normal immunity but also of neoplasia affecting these cells. It is now abundantly clear that certain lymphocytes are conditioned by the thymus (hence their designation as T-cells) and acquire the ability to mediate ...
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AUTOANTIBODY AGAINST B LYMPHOCYTES
The Lancet, 1977The sera of 20 out of 99 (20%) normal males and females were shown to have antibodies that kill their own B lymphocytes. The sera were specifically cytotoxic to B lymphocytes and not T lymphocytes. Allogeneic B lymphocytes were also killed by these autocytotoxins.
M S, Park, P I, Terasaki, D, Bernoco
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Mammalian B lymphocyte precursors
Developmental & Comparative Immunology, 1984Ce l l u l a r spec ia l i za t i on in the immune response is epitomized by the d i v i s i o n of lymphocytes into func t iona l subsets. The most basic such d i v i s i o n involves ce l l s with eas i l y detectable ce l l surface immunoglobulin (s lg +, B c e l l s ) and ce l l s a r i s ing from the thymus (T ce l l s ) which d i f f e r s u b s ...
K S, Landreth, P W, Kincade
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Trafficking of Adoptively Transferred B Lymphocytes in B-Lymphocyte-Deficient Mice
Journal of Experimental Biology, 1997ABSTRACT Many studies have investigated the fate of adoptively transferred lymphocytes in recipient mice, although little is known of the sites where these transferred cells reside at particular time points. Using flow cytometry, we analyzed the trafficking pattern of adoptively transferred naive B cells into the lymphoid organs of ...
R, Roth, M J, Mamula
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The Journal of Immunology, 1978
Abstract After surface immunoglobulin-bearing (sIg+) cells are removed from mouse bone marrow on an anti-Ig immunoadsorbent column, precursors of bone marrow-derived (B) lymphocytes can be observed to differentiate in vitro. Expression of sIg occurs spontaneously on approximately 50% of the small lymphocytes during 3 days in culture. The
Sally S Fairchild, J John Cohen
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Abstract After surface immunoglobulin-bearing (sIg+) cells are removed from mouse bone marrow on an anti-Ig immunoadsorbent column, precursors of bone marrow-derived (B) lymphocytes can be observed to differentiate in vitro. Expression of sIg occurs spontaneously on approximately 50% of the small lymphocytes during 3 days in culture. The
Sally S Fairchild, J John Cohen
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Interleukins for B lymphocytes
Survey of Immunologic Research, 1983The above reviews our developing knowledge on the nature of B cell-specific interleu-kins. It may be anticipated that in the next several years, considerable progress will be made in understanding the physicochemical properties of these factors, their time and nature of action, and the nature of their receptors.
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Blood, 2014
In this issue of Blood, Mallampati et al provide mechanistic insight into the functions of the transcription factor Sox4 in pro-B lymphocytes using both gain-of-function and loss-of-function approaches combined with global gene expression and genome-wide transcription factor binding analysis.
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In this issue of Blood, Mallampati et al provide mechanistic insight into the functions of the transcription factor Sox4 in pro-B lymphocytes using both gain-of-function and loss-of-function approaches combined with global gene expression and genome-wide transcription factor binding analysis.
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Antigen Receptors on B Lymphocytes
Annual Review of Immunology, 1992Recent studies on the structure of the B cell antigen receptor demonstrate that the membrane-bound and antigen-binding immunoglobulin molecules are noncovalently associated with a heterodimer of two novel transmembrane proteins. The B cell antigen receptor is thus a multicomponent receptor complex whose structural features are similar to those of the ...
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B-Lymphocytes in Carcinogenesis
1979Cancer is not a single disease entity; the term is applied to a large number of diseases in which the abnormal and continued growth of cells of a given tissue is expressed. The immunologic mechanism responsible for the rejection of solid tumors in experimental animals is generally thought to be the same as that responsible for homograft rejection, i.e.,
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