Results 11 to 20 of about 37,865 (209)

BvrR From Brucella abortus Induces Neuroinflammation Through IRE1-Mediated Activation of ATF2 and NF-κB. [PDF]

Microbiologyopen
This study demonstrates that the BvrR induces neuroinflammation. In microglial cells, BvrR expression localizes to the endoplasmic reticulum (ER), causing ER expansion and activating the stress sensor IRE1. Phosphorylated IRE1 subsequently drives the activation and nuclear translocation of transcription factors ATF2 and NF‐κB p65.
Wang Z, Yu X, Liu B, Ren D.
europepmc   +2 more sources

Mouse Cytokine Profiles Associated withBrucella abortusRB51 Vaccination orB. abortus2308 Infection [PDF]

Infection and Immunity, 2001
ABSTRACTThis study indicated that mice immunized withBrucella abortusRB51 bacteria and subsequently challenged withB. abortus2308 were protected from reinfection. After vaccination, both Th1 and Th2 cytokine patterns were observed. Of those, the early production of gamma interferon seems to have the prominent role in inducing an immunologically based ...
P, Pasquali, R, Adone, L C, Gasbarre, C, Pistoia, F, Ciuchini   +4 more
openaire   +2 more sources

Brucella abortus-Stimulated Platelets Activate Brain Microvascular Endothelial Cells Increasing Cell Transmigration through the Erk1/2 Pathway

Pathogens, 2020
Central nervous system invasion by bacteria of the genus Brucella results in an inflammatory disorder called neurobrucellosis. A common feature associated with this pathology is blood–brain barrier (BBB) activation.
Ana María Rodríguez, Aldana Trotta, Agustina P. Melnyczajko, M. Cruz Miraglia, Kwang Sik Kim, M. Victoria Delpino, Paula Barrionuevo, Guillermo Hernán Giambartolomei   +7 more
doaj   +1 more source

Serological and Molecular Investigation of Brucella Species in Dogs in Pakistan [PDF]

, 2019
Brucellosis is an important bacterial zoonosis caused by B. abortus and B. melitensis in Pakistan. The status of canine brucellosis caused by B. canis remains obscure.
Hammad Hussain, Muhammad, Iqbal, Mudassar, Jamil, Tariq, Khan, Iahtasham, Melzer, Falk, Neubauer, Heinrich, Saqib, Muhammad, Schwarz, Stefan   +7 more
core   +2 more sources

Proteomic Analysis of Stationary Growth Stage Adaptation and Nutritional Deficiency Response of Brucella abortus

Frontiers in Microbiology, 2020
Brucellosis, an important bacterial zoonosis caused by Brucella species, has drawn increasing attention worldwide. As an intracellular pathogen, the ability of Brucella to deal with stress within the host cell is closely related to its virulence.
Jianghua Yang, Mengzhi Liu, Jinling Liu, Baoshan Liu, Chuanyu He, Zeliang Chen, Zeliang Chen, Zeliang Chen, Zeliang Chen   +8 more
doaj   +1 more source

Brucella abortus Infection of Placental Trophoblasts Triggers Endoplasmic Reticulum Stress-Mediated Cell Death and Fetal Loss via Type IV Secretion System-Dependent Activation of CHOP. [PDF]

, 2019
Subversion of endoplasmic reticulum (ER) function is a feature shared by multiple intracellular bacteria and viruses, and in many cases this disruption of cellular function activates pathways of the unfolded protein response (UPR).
Atluri, Vidya L, Byndloss, Mariana X, Celli, Jean, de Jong, Maarten F, English, Bevin C, Kerrinnes, Tobias, Miller, Cheryl N, O'Riordan, Mary, Roop, R Martin, Seyffert, Núbia, Tsai, April Y, Tsolis, Renée M, Walker, Gregory T, Winter, Maria G, Young, Briana M   +14 more
core   +1 more source

Inhibition of Osteoblast Function by Brucella abortus is Reversed by Dehydroepiandrosterone and Involves ERK1/2 and Estrogen Receptor

Frontiers in Immunology, 2018
Brucella abortus induces an inflammatory response that stimulates the endocrine system resulting in the secretion of cortisol and dehydroepiandrosterone (DHEA).
María Virginia Gentilini, Ayelén Ivana Pesce Viglietti, Paula Constanza Arriola Benitez, Andrea Elena Iglesias Molli, Gloria Edith Cerrone, Guillermo Hernán Giambartolomei, María Victoria Delpino   +6 more
doaj   +1 more source

Brucella abortus-infected B cells induce osteoclastogenesis

Microbes and Infection, 2016
Brucella abortus is an intracellular bacterium that establishes lifelong infections in livestock and humans although the mechanisms of its chronicity are poorly understood. Activated B cells have long lifespan and B. abortus infection activates B cells. Our results indicate that the direct infection of B cells with B.
Pesce Viglietti, Ayelén Ivana, Arriola Benitez, Paula Constanza, Giambartolomei, Guillermo Hernan, Delpino, María Victoria   +3 more
openaire   +3 more sources

Identification, Genotyping and Antimicrobial Susceptibility Testing of Brucella spp. Isolated from Livestock in Egypt [PDF]

, 2019
Brucellosis is a highly contagious zoonosis worldwide with economic and public health impacts. The aim of the present study was to identify Brucella (B.) spp. isolated from animal populations located in different districts of Egypt and to determine their
El-Adawy, Hosny, Elschner, Mandy C., Khan, Aman Ullah, Melzer, Falk, Moawad, Amira A., Neubauer, Heinrich, Ramadan, Eman Shawkat, Roesler, Uwe, Sayour, Ashraf E., Shell, Waleed S.   +9 more
core   +1 more source

Penggunaan Imunostik sebagai Uji Serologi untuk Deteksi Brucella abortus pada Sapi (APPLICATION IMMUNOSTICK ASSAY FOR SEROLOGICAL TEST BRUCELLA ABORTUS IN BOVINE)

Jurnal Veteriner, 2018
Serological test is one of diagnostic method to detect pathogenicity brucella.  Several methods are being improving such as Rose Bengal Test (RBT), Complement Fixation Test (CFT) dan Enzyme-linked Immunosorbent Assay (ELISA).
Dhevie Kenny Astarina, Eko Sugeng Pribadi, Fachriyan Hasmi Pasaribu   +2 more
doaj   +1 more source