Results 51 to 60 of about 37,865 (209)

The Curious Case of CysE: Diversity and Distribution of Serine Acetyltransferases in Bacteria

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Serine acetyltransferase (CysE) is a member of the left‐handed β‐helix family of acetyltransferases that catalyze the rate limiting step in de novo cysteine biosynthesis. There are two isoforms of CysE that differ in length, with the shorter isoform lacking approximately 76 amino acids at the N‐terminus of the protein from the serine ...
Keely E. A. Oldham, Adele K. Williamson, Emily K. Grout, Joanna L. Hicks   +3 more
wiley   +1 more source

Adaptation mechanisms of Brucella abortus to low magnesium ion stress

BMC Veterinary Research
Background Brucella abortus, a facultative intracellular pathogenic bacterium that usually causes diseases under animals and humans, can survive and replicate within phagocytic cells. Within the host cells, B.
Hengtai Wang, Lang Lv, Yike Huang, Hui Jiang, Xiaowen Yang, Jiabo Ding, Liangquan Zhu, Lei Xu, Huaiming Sang, Jianxia Jiang, Nan Wang, Peng Li   +11 more
doaj   +1 more source

Proteomic Analysis of Membrane Blebs of Brucella abortus 2308 and RB51 and Their Evaluation as an Acellular Vaccine

Frontiers in Microbiology, 2019
Membrane blebs are released from Gram-negative bacteria, however, little is known about Brucella blebs. This work pursued two objectives, the first was to determine and identify the proteins in the membrane blebs by proteomics and in silico analysis. The
Minerva Araiza-Villanueva, Eric Daniel Avila-Calderón, Eric Daniel Avila-Calderón, Leopoldo Flores-Romo, Juana Calderón-Amador, Nammalwar Sriranganathan, Hamzeh Al Qublan, Sharon Witonsky, Sharon Witonsky, Ma. Guadalupe Aguilera-Arreola, María del Socorro Ruiz-Palma, María del Socorro Ruiz-Palma, Enrico A. Ruiz, Francisco Suárez-Güemes, Zulema Gómez-Lunar, Araceli Contreras-Rodríguez   +15 more
doaj   +1 more source

Influence of platelet-activating factor receptor (PAFR) on Brucella abortus infection: implications for manipulating the phagocytic strategy of B. abortus [PDF]

BMC Microbiology, 2016
Brucella abortus is an intracellular pathogen which can infect and persist in host cells through multiple interactions. Above all, its interaction to host cell receptor is important to understand the pathogenic mechanisms of B. abortus. Accordingly, we demonstrated that platelet-activating factor receptor (PAFR) affects host cell response against B ...
Lee, Jin Ju, Simborio, Hannah Leah, Reyes, Alisha Wehdnesday Bernardo, Hop, Huynh Tan, Arayan, Lauren Togonon, Lee, Hu Jang, Min, Wongi, Her, Moon, Rhee, Man Hee, Watarai, Masahisa, Chang, Hong Hee, Kim, Suk   +11 more
openaire   +2 more sources

The small protein CydX is required for function of cytochrome bd oxidase in Brucella abortus. [PDF]

, 2012
A large number of hypothetical genes potentially encoding small proteins of unknown function are annotated in the Brucella abortus genome. Individual deletion of 30 of these genes identified four mutants, in BAB1_0355, BAB2_0726, BAB2_0470, and BAB2_0450
de Jong, Maarten F, den Hartigh, Andreas B, Rolán, Hortensia G, Roux, Christelle M, Sun, Yao-Hui, Tsolis, Renée M   +5 more
core   +3 more sources

Structural Analysis and Inhibitor Modeling of Bacterioferritin From Brucella abortus

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Iron homeostasis in various pathogenic bacteria is regulated by bacterioferritins (Bfr) which function to store Fe3+ and release Fe2+ as needed for metabolic processes. The Bfr structure consists of 18 kDa subunits in which dimer pairs bind a heme molecule and are assembled into a highly symmetrical 24‐meric spherical structure with an ...
Lijun Liu, Elizabeth K. Harmon, Justin K. Craig, Huili Yao, Kevin P. Battaile, David K. Johnson, Sandhya Subramanian, Wesley C. Van Voorhis, Mario Rivera, Scott Lovell   +9 more
wiley   +1 more source

Host Interferon-Gamma Inducible Protein Contributes to Brucella Survival

Frontiers in Cellular and Infection Microbiology, 2012
Brucella spp. are highly adapted intracellular pathogens of mammals that cause chronic infections while surving and replicating in host monocytes and macrophages.
Jennifer eRitchie, Adam eRupper, James eCardelli, Bryan eBellaire   +3 more
doaj   +1 more source

Fatal spinal cord compression in a horse with chronic actinobacterial cranial nuchal bursitis

Equine Veterinary Education, EarlyView.
Summary A 14‐year‐old warmblood gelding was managed for waxing and waning cranial nuchal bursitis for 2 years. Intensive medical and surgical management was not curative, and the patient was subjected to euthanasia after becoming acutely recumbent. Ante‐mortem and post‐mortem next generation sequencing of bursal tissue and post‐mortem conventional PCR ...
H. Mesch, C. Frank, J. B. Daniels, E. Acutt, E. Contino   +4 more
wiley   +1 more source

Typing discrepancy between phenotypic and molecular characterization revealing an emerging biovar 9 variant of smooth phage-resistant B. abortus strain 8416 in China

Frontiers in Microbiology, 2015
A newly isolated smooth colony morphology phage-resistant (SPR) strain 8416 isolated from a 45-year-old cattle farm cleaner with clinical features of brucellosis in China was reported.
YaoXia eKang, YaoXia eKang, XuMing eLi, DongRi ePiao, GuoZhong eTian, Hai eJiang, EnHou eJia, Liang eLin, BuYun eCui, Yung-Fu eChang, XiaoKui eGuo, Yongzhang eZhu, Yongzhang eZhu   +12 more
doaj   +1 more source

Adrenal steroids modulate the immune response during Brucella abortus infection by a mechanism that depends on the regulation of cytokine production [PDF]

, 2015
Human brucellosis is a protean disease with a diversity of clinical signs and symptoms resulting from infection with Brucella species. Recent reports suggest a cross-regulation between adrenal steroids (cortisol and dehydroepiandrosterone [DHEA]) and the
Alsalameh S, Boyum A, Czarniecki CW, Hibbs MS, Nagase H, O'Neill S, Reimold AM, Schneeberger EE, Ting JP, Young EJ, Zhan Y   +10 more
core   +1 more source