Results 81 to 90 of about 4,634 (162)

Glycoproteomics and Its Role in Understanding Bacterial O‐Linked Glycosylation

PROTEOMICS, Volume 25, Issue 21-22, Page 160-176, November 2025.
ABSTRACT Protein glycosylation is now recognized as a ubiquitous process observed in all domains of life. Within bacterial species, carbohydrates can be attached to multiple residues with glycosylation of serine, threonine, or tyrosine residues via their hydroxyl side chains referred to as O‐linked glycosylation.
Kristian I. Karlic, Hamza Tahir, Nichollas E. Scott   +2 more
wiley   +1 more source

The Changing Transplant Landscape in the Era of Elexacaftor/Tezacaftor/Ivacaftor: A Word of Caution

Clinical Transplantation, Volume 39, Issue 10, October 2025.
ABSTRACT Background Elexacaftor/tezacaftor/ivacaftor (ETI) has dramatically changed the landscape of cystic fibrosis (CF) care, including in those who require lung transplantation. The objectives of the study were to describe the cohort demographics and outcomes of primary lung transplant recipients before and after the availability of ETI.
Julie Semenchuk, Eliza Tuff‐Gordon, Xiayi Ma, Jenna Sykes, Stephanie Y. Cheng, Meghan Aversa, Cecilia Chaparro, Elizabeth Tullis, Anne L. Stephenson   +8 more
wiley   +1 more source

Diversity of the parB and repA genes of the Burkholderia cepacia complex and their utility for rapid identification of Burkholderia cenocepacia

BMC Microbiology, 2008
Background Burkholderia cenocepacia is the most prominent species of the B. cepacia complex (Bcc), a group of nine closely related and difficult to identify bacteria that cause serious infections in patients with cystic fibrosis.
Dowson Christopher G, Baldwin Adam, Drevinek Pavel, Mahenthiralingam Eshwar   +3 more
doaj   +1 more source

The involvement of phenylalanine and phenylacetic acid in regulation of pathogenicity in B. cenocepacia K56-2

, 2023
Burkholderia cenocepacia is a gram-negative bacterium known for causing persistent lung infections in individuals living with cystic fibrosis. These infections are highly communicable and difficult to treat due to intrinsic and acquired antibiotic resistance.
openaire   +1 more source

Persistence of Burkholderia pseudomallei, B. multivorans and B. cenocepacia : differential analysis by proteomics and activation of phosphoinositide-3 kinase

, 2013
Persistent infection in mammalian hosts is one intriguing aspect of the study of human diseases. In order to gain insight into the establishment of persistence, this thesis will evaluate the bacterial and host components associated with persistence of two groups within the Burkholderia genus: Burkholderia pseudomallei and Burkholderia cepacia complex ...
openaire   +1 more source

Gene expression changes linked to antimicrobial resistance, oxidative stress, iron depletion and retained motility are observed when Burkholderia cenocepacia grows in cystic fibrosis sputum

BMC Infectious Diseases, 2008
Background Bacteria from the Burkholderia cepacia complex (Bcc) are the only group of cystic fibrosis (CF) respiratory pathogens that may cause death by an invasive infection known as cepacia syndrome.
Ketchell Ian, Jones Andrew M, Ge Zhaoping, Holden Matthew TG, Drevinek Pavel, Gill Ryan T, Mahenthiralingam Eshwar   +6 more
doaj   +1 more source

A Polyclonal Antibody against a Burkholderia cenocepacia OmpA-like Protein Strongly Impairs Pseudomonas aeruginosa and B. multivorans Virulence

Vaccines
Despite advances in therapies, bacterial chronic respiratory infections persist as life-threatening to patients suffering from cystic fibrosis (CF). Pseudomonas aeruginosa and bacteria of the Burkholderia cepacia complex are among the most difficult of these infections to treat, due to factors like their resistance to multiple antibiotics and ability ...
António M. M. Seixas, Sara C. Gomes, Carolina Silva, Leonilde M. Moreira, Jorge H. Leitão, Sílvia A. Sousa   +5 more
openaire   +3 more sources

Genetic relationships among Italian and Mexican maize-rhizosphere Burkholderia cepacia complex (BCC) populations belonging to Burkholderia cenocepacia IIIB and BCC6 group

BMC Microbiology, 2011
Background A close association between maize roots and Burkholderia cepacia complex (BCC) bacteria has been observed in different locations globally.
Bevivino Annamaria, Costa Barbara, Cantale Cristina, Cesarini Silvia, Chiarini Luigi, Tabacchioni Silvia, Caballero-Mellado Jesus, Dalmastri Claudia   +7 more
doaj   +1 more source

Mutations Affecting Cellular Levels of Cobalamin (Vitamin B₁₂) Confer Tolerance to Bactericidal Antibiotics in Burkholderia cenocepacia

Journal of Microbiology and Biotechnology
The Burkholderia cepacia complex (Bcc) consists of opportunistic pathogens known to cause pneumonia in immunocompromised individuals, especially those with cystic fibrosis. Treating Bcc pneumonia is challenging due to the pathogens' high multidrug resistance.
Lee, Dongju, Park, Jongwook, Kim, Heenam Stanley   +2 more
openaire   +2 more sources

Assessment of three Resistance-Nodulation-Cell Division drug efflux transporters of Burkholderia cenocepacia in intrinsic antibiotic resistance

BMC Microbiology, 2009
Background Burkholderia cenocepacia are opportunistic Gram-negative bacteria that can cause chronic pulmonary infections in patients with cystic fibrosis.
Venturi Vittorio, Bertani Iris, Milano Anna, Bazzini Silvia, Flannagan Ronald S, Pasca Maria R, Buroni Silvia, Valvano Miguel A, Riccardi Giovanna   +8 more
doaj   +1 more source